Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Sean R. Connell"'
Autor:
Xu Han, Cecilia D'Angelo, Ainara Otamendi, Javier O. Cifuente, Elisa de Astigarraga, Borja Ochoa-Lizarralde, Martin Grininger, Francoise H. Routier, Marcelo E. Guerin, Jana Fuehring, Oier Etxebeste, Sean R. Connell
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Invasive aspergillosis is one of the most serious clinical invasive fungal infections, resulting in a high case fatality rate among immunocompromised patients. The disease is caused by saprophytic molds in the genus Aspergillus, including As
Externí odkaz:
https://doaj.org/article/232e426a0a684ce694dd55e5be755b6b
Autor:
Soledad Stagnoli, Francesca Peccati, Sean R. Connell, Ane Martinez-Castillo, Diego Charro, Oscar Millet, Chiara Bruzzone, Asis Palazon, Ana Ardá, Jesús Jiménez-Barbero, June Ereño-Orbea, Nicola G. A. Abrescia, Gonzalo Jiménez-Osés
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Two years after its emergence, the coronavirus disease-2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) remains difficult to control despite the availability of several vaccines. The extensively glycosyl
Externí odkaz:
https://doaj.org/article/0bb70785222547e2b682896cbcf64c65
Autor:
Corina G. Heidrich, Sanya Mitova, Andreas Schedlbauer, Sean R. Connell, Paola Fucini, Judith N. Steenbergen, Christian Berens
Publikováno v:
Antibiotics, Vol 5, Iss 4, p 32 (2016)
Omadacycline is an aminomethylcycline antibiotic with potent activity against many Gram-positive and Gram-negative pathogens, including strains carrying the major efflux and ribosome protection resistance determinants. This makes it a promising candi
Externí odkaz:
https://doaj.org/article/d445c41d292542c98e6f16a19e00af96
Publikováno v:
Molecular Microbiology. 119:630-639
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f8822309c8268a958c8d0fe7e78343a
https://doi.org/10.1111/mmi.15059
https://doi.org/10.1111/mmi.15059
Autor:
Mathew McLaren, Patricia Gil-Diez, Michail N. Isupov, Rebecca Conners, Lavinia Gambelli, Vicki Gold, Andreas Walter, Sean R. Connell, Bryony Williams, Bertram Daum
Translational control is an essential process for the cell to adapt to varying physiological or environmental conditions. To survive adverse conditions such as low nutrient levels, translation can be shut down almost entirely by inhibiting ribosomal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a007eef4682e81b7229f08b46921fb4
https://doi.org/10.1101/2022.04.29.490036
https://doi.org/10.1101/2022.04.29.490036
Autor:
T. Kaminishi, Retina Çapuni, C. Gualerzi, Sean R. Connell, B. Ochoa-Lizarralde, Paola Fucini, A. Schedlbauer, X. Han, Pohl Milón, Attilio Fabbretti
The ribosome is a major target for antibiotics owing to its essential cellular role in protein synthesis. Structural analysis of ribosome-antibiotic complexes provides insight into the molecular basis for their inhibitory action and highlights possib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bced00caafe6c9d98ccb66ffe8927cb0
https://doi.org/10.1101/2021.11.29.470217
https://doi.org/10.1101/2021.11.29.470217
Autor:
Andreas Schedlbauer, Sean R. Connell, Elisa de Astigarraga, Jorge P. López-Alonso, T. Kaminishi, Neha Dhimole, B. Ochoa-Lizarralde, Paola Fucini, Tammo Diercks, Retina Çapuni, José Luis Lavín, David Gil-Carton, Idoia Iturrioz
Publikováno v:
Science Advances
This study highlights the molecular mechanisms of four assembly factors in folding the ribosomal central decoding region.
While a structural description of the molecular mechanisms guiding ribosome assembly in eukaryotic systems is emerging, bac
While a structural description of the molecular mechanisms guiding ribosome assembly in eukaryotic systems is emerging, bac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4796413baf4c4d8b7a54f3bc68b7e695
https://doi.org/10.1126/sciadv.abf7547
https://doi.org/10.1126/sciadv.abf7547
Autor:
Sean R. Connell, Natasha Browne-Marke, Igor Y. Morozov, Paola Fucini, Amir Mossanen-Parsi, Daniele Parisi, Izwan Bharudin, Olga Mayans, Mark X. Caddick
Publikováno v:
MOLECULAR MICROBIOLOGY
The role of post‐transcriptional RNA modification is of growing interest. One example is the addition of non‐templated uridine residues to the 3′ end of transcripts. In mammalian systems, uridylation is integral to cell cycle control of histone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57293bccfc0895f17aa932ce4113a835
Backbone and sidechain NMR assignments for the ribosome maturation factor RbfA from Escherichia coli
Autor:
Andreas Schedlbauer, Idoia Iturrioz, Borja Ochoa-Lizarralde, Retina Çapuni, Xu Han, Elisa de Astigarraga, Tammo Diercks, Paola Fucini, Sean R. Connell
Publikováno v:
Biomolecular NMR assignments. 14(2)
RbfA (ribosome binding factor A; 15.2 kDa) is a protein involved in ribosome biogenesis and has been shown to be important for growth at low temperatures and to act as a suppressor for a cold-sensitive mutation (C23U) in the ribosomal RNA of the smal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6cba16e567a5a50cbee9fc70498f29
https://pubmed.ncbi.nlm.nih.gov/32671633
https://pubmed.ncbi.nlm.nih.gov/32671633
Backbone and sidechain NMR assignments for the ribosome maturation factor RimP from Escherichia coli
Autor:
Xu Han, Idoia Iturrioz, B. Ochoa-Lizarralde, Paola Fucini, Tammo Diercks, Andreas Schedlbauer, Elisa de Astigarraga, Retina Çapuni, Sean R. Connell
Publikováno v:
Biomolecular NMR assignments. 14(2)
Ribosome biogenesis is an energetically expensive and complex cellular process that involves the coordinated folding of the ribosomal RNA and dozens of ribosomal proteins. It proceeds along multiple parallel pathways and is guided by trans-acting fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bbb20c5188da61bfa3c03504bdc19c9
https://pubmed.ncbi.nlm.nih.gov/32303998
https://pubmed.ncbi.nlm.nih.gov/32303998