Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sean R Cuddy"'
Autor:
Sean R Cuddy, Austin R Schinlever, Sara Dochnal, Philip V Seegren, Jon Suzich, Parijat Kundu, Taylor K Downs, Mina Farah, Bimal N Desai, Chris Boutell, Anna R Cliffe
Publikováno v:
eLife, Vol 9 (2020)
Herpes simplex virus-1 (HSV-1) establishes a latent infection in neurons and periodically reactivates to cause disease. The stimuli that trigger HSV-1 reactivation have not been fully elucidated. We demonstrate HSV-1 reactivation from latently infect
Externí odkaz:
https://doaj.org/article/0fb97c7a33404ae3886ae03f37e70bc9
Autor:
Sean R. Cuddy, Anna R. Cliffe
Publikováno v:
Journal of Virology. 97
Innate immune responses can impact different stages of viral life cycles. Herpes simplex virus latent infection of neurons and subsequent reactivation provide a unique context for immune responses to intersect with different stages of infection.
Autor:
Austin R Schinlever, Eugene Ke, Sara Dochnal, Chris Boutell, Hiam Baidas, Sean R Cuddy, Jon B. Suzich, Aleksandra Babnis, Anna R. Cliffe
Publikováno v:
EMBO Rep
Herpes simplex virus (HSV) establishes latent infection in long‐lived neurons. During initial infection, neurons are exposed to multiple inflammatory cytokines but the effects of immune signaling on the nature of HSV latency are unknown. We show th
Autor:
Austin R Schinlever, Sara Dochnal, Anna R. Cliffe, Eugene Ke, Hiam Baidas, Sean R Cuddy, Aleksandra Babnis, Jon B. Suzich, Chris Boutell
Herpes simplex virus (HSV) establishes latent infection in long-lived neurons. During initial infection, neurons are exposed to multiple inflammatory cytokines but the effects of immune signaling on the nature of HSV latency is unknown. We show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f27f184f1369979da0999545b30eb6a
https://doi.org/10.1101/2021.02.03.429616
https://doi.org/10.1101/2021.02.03.429616
Autor:
Mina Farah, Sean R Cuddy, Parijat Kundu, Chris Boutell, Philip V. Seegren, Austin R Schinlever, Anna R. Cliffe, Taylor K Downs, Sara Dochnal, Jon B. Suzich, Bimal N. Desai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2012f87b5503d8c76eeca70098c8414e
https://doi.org/10.7554/elife.58037.sa2
https://doi.org/10.7554/elife.58037.sa2
Autor:
Mina Farah, Austin R Schinlever, Sara Dochnal, Jon B. Suzich, Sean R Cuddy, Anna R. Cliffe, Chris Boutell
Publikováno v:
Proceedings, Vol 50, Iss 91, p 91 (2020)
Herpes Simplex Virus (HSV) establishes a latent infection in neurons, in which viral transcription is restricted and viral promoters are associated with heterochromatin. In response to certain stimuli, the virus reactivates to permit transmission. Th
Autor:
Mina Farah, Anna R. Cliffe, Chris Boutell, Sean R Cuddy, Austin R Schinlever, Jon B. Suzich, Bimal N. Desai, Sara Dochnal, Taylor K Downs, Parijat Kundu
Herpes Simplex Virus (HSV) establishes a latent infection in neurons and periodically reactivates to cause disease. The neuronal stimuli that trigger HSV reactivation have not been fully elucidated. Here we demonstrate that HSV reactivation can be in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b427ba5846108786278ebc169823c9c
Autor:
Taylor K Downs, Anna R. Cliffe, Sara Dochnal, Mina Farah, Chris Boutell, Jon B. Suzich, Austin R Schinlever, Parijat Kundu, Bimal N. Desai, Philip V. Seegren, Sean R Cuddy
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Herpes simplex virus-1 (HSV-1) establishes a latent infection in neurons and periodically reactivates to cause disease. The stimuli that trigger HSV-1 reactivation have not been fully elucidated. We demonstrate HSV-1 reactivation from latently infect
Publikováno v:
Autophagy
Lysosomal degradation of protein aggregates and damaged organelles is essential for maintaining cellular homeostasis. This process in neurons is challenging due to their highly polarized architecture. While enzymatically active degradative lysosomes
Publikováno v:
Cell reports
Cell Reports, Vol 28, Iss 1, Pp 51-64.e4 (2019)
Cell Reports, Vol 28, Iss 1, Pp 51-64.e4 (2019)
SUMMARY Neurons face the challenge of maintaining cellular homeostasis through lysosomal degradation. While enzymatically active degradative lysosomes are enriched in the soma, their axonal trafficking and positioning and impact on axonal physiology