Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sean Patmore"'
Autor:
Chia Yin Goh, Sean Patmore, Albert Smolenski, Jane Howard, Shane Evans, Jamie O'Sullivan, Amanda McCann
Publikováno v:
Translational Oncology, Vol 14, Iss 4, Pp 101033- (2021)
Breast cancer is the most common female cancer globally, with approximately 12% of patients eventually developing metastatic disease. Critically, limited effective treatment options exist for metastatic breast cancer. Recently, von Willebrand factor
Externí odkaz:
https://doaj.org/article/9bdecf952f244736ada35ae53dfed2bc
Autor:
Claire Comerford, Sukhraj Pal Singh Dhami, Philip Murphy, Sean Patmore, Soracha Ward, Nadiya Pushkar, Ulrich Budde, Ellie Karampini, James S. O'Donnell, Siobhan Glavey, John Quinn, Jamie M. O'Sullivan
Publikováno v:
Thrombosis Research. 226:136-140
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb582474cc72bff6a0f9e3b15c13696c
https://doi.org/10.1016/j.thromres.2023.04.014
https://doi.org/10.1016/j.thromres.2023.04.014
Autor:
Sukhraj Pal Singh Dhami, Sean Patmore, Claire Comerford, Ciara M. Byrne, Brenton Cavanagh, John Castle, Cliona C. Kirwan, Martin Kenny, Ingmar Schoen, James S. O'Donnell, Jamie M. O'Sullivan
Publikováno v:
Journal of Thrombosis and Haemostasis. 20:2350-2365
Breast cancer results in a three- to four-fold increased risk of venous thromboembolism (VTE), which is associated with reduced patient survival. Despite this, the mechanisms underpinning breast cancer-associated thrombosis remain poorly defined. Tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b88d1e6fa8d856c8ff041b6cc4a776
https://doi.org/10.1111/jth.15794
https://doi.org/10.1111/jth.15794
Publikováno v:
Seminars in Thrombosis and Hemostasis. 47:139-149
The association between cancer and venous thromboembolism (VTE) has been established for more than 150 years. Nevertheless, cancer-associated thrombosis still remains a major clinical challenge and is associated with significant morbidity and mortali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::050aa8d4c68b8d6348c66a8c46d5e560
https://doi.org/10.1055/s-0041-1722863
https://doi.org/10.1055/s-0041-1722863
Autor:
Margaret Nolan, Mary Byrne, Roger J. S. Preston, Sonia Aguila, Kevin Ryan, Alain Chion, Catriona Keenan, Paula D. James, Jamie M. O’Sullivan, Michelle Lavin, Teresa M. Brophy, Jorge Di Paola, George D. Trahan, Anjali Patel, Niamh M O'Connell, James S. O’Donnell, Kenneth L. Jones, Niall Dalton, Sean Patmore
Publikováno v:
Blood. 133:1585-1596
Glycan determinants on von Willebrand factor (VWF) play critical roles in regulating its susceptibility to proteolysis and clearance. Abnormal glycosylation has been shown to cause von Willebrand disease (VWD) in a number of different mouse models. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb3f28bf152cc732420aaaf63c7de428
https://doi.org/10.1182/blood-2018-09-874636
https://doi.org/10.1182/blood-2018-09-874636
Autor:
Jane Howard, Amanda McCann, Albert Smolenski, Jamie M. O’Sullivan, Sean Patmore, Chia Yin Goh, Shane Evans
Publikováno v:
Translational Oncology, Vol 14, Iss 4, Pp 101033-(2021)
Translational Oncology
Translational Oncology
Highlights • VWF plays an important role in breast tumour progression and metastasis. • Patients with metastatic breast cancer have significantly elevated plasma VWF. • Increased levels of highly adhesive VWF may regulate platelet-tumour intera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d9bf2ee329c4fe08546a6360ce51f0f
http://www.sciencedirect.com/science/article/pii/S1936523321000255
http://www.sciencedirect.com/science/article/pii/S1936523321000255
Publikováno v:
Journal of thrombosis and haemostasis : JTHREFERENCES. 18(10)
Von Willebrand factor (VWF) is a multimeric procoagulant plasma glycoprotein that mediates platelet adhesion along the endothelium. In addition to its role maintaining normal hemostasis, more recently novel biological functions for VWF have been desc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36be0067cbc27ac9afb390e72c67a68
https://pubmed.ncbi.nlm.nih.gov/32573945
https://pubmed.ncbi.nlm.nih.gov/32573945
Autor:
Philip Murphy, John Quinn, Siobhan Glavey, Jamie M. O’Sullivan, Claire Comerford, Sean Patmore, Sukhraj Pal Singh Dhami
Publikováno v:
Blood. 138:3141-3141
Introduction Multiple Myeloma (MM) remains an incurable disease and is associated with high rates of venous thromboembolism (VTE), the biological basis for which is not fully understood. Critically, VTE is associated with increased mortality in MM. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dbcde1997e2dbcc54ecc75ebf0bf4d3
https://doi.org/10.1182/blood-2021-149134
https://doi.org/10.1182/blood-2021-149134