Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Sean P. Walsh"'
Publikováno v:
eLife, Vol 13 (2024)
Recent advances in connectomics and neurophysiology make it possible to probe whole-brain mechanisms of cognition and behavior. We developed a large-scale model of the multiregional mouse brain for a cardinal cognitive function called working memory,
Externí odkaz:
https://doaj.org/article/f5048ff3063f466ca9db3afc6e3b2002
Autor:
Lucija Rapan, Sean Froudist-Walsh, Meiqi Niu, Ting Xu, Ling Zhao, Thomas Funck, Xiao-Jing Wang, Katrin Amunts, Nicola Palomero-Gallagher
Publikováno v:
eLife, Vol 12 (2023)
Based on quantitative cyto- and receptor architectonic analyses, we identified 35 prefrontal areas, including novel subdivisions of Walker’s areas 10, 9, 8B, and 46. Statistical analysis of receptor densities revealed regional differences in latera
Externí odkaz:
https://doaj.org/article/ec1e2014fe6a429d822a979acbe4e927
Autor:
Enrico D’Ambrosio, Giulio Pergola, Antonio F. Pardiñas, Tarik Dahoun, Mattia Veronese, Leonardo Sportelli, Paolo Taurisano, Kira Griffiths, Sameer Jauhar, Maria Rogdaki, Michael A. P. Bloomfield, Sean Froudist-Walsh, Ilaria Bonoldi, James T. R. Walters, Giuseppe Blasi, Alessandro Bertolino, Oliver D. Howes
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The D2 dopamine receptor (D2R) is the primary site of the therapeutic action of antipsychotics and is involved in essential brain functions relevant to schizophrenia, such as attention, memory, motivation, and emotion processing. Moreover, t
Externí odkaz:
https://doaj.org/article/dbe39ccf3d614d2d8f15ab9ffca373c2
Autor:
P. Christiaan Klink, Jean-François Aubry, Vincent P. Ferrera, Andrew S. Fox, Sean Froudist-Walsh, Béchir Jarraya, Elisa E. Konofagou, Richard J. Krauzlis, Adam Messinger, Anna S. Mitchell, Michael Ortiz-Rios, Hiroyuki Oya, Angela C. Roberts, Anna Wang Roe, Matthew F.S. Rushworth, Jérôme Sallet, Michael Christoph Schmid, Charles E. Schroeder, Jordy Tasserie, Doris Y. Tsao, Lynn Uhrig, Wim Vanduffel, Melanie Wilke, Igor Kagan, Christopher I. Petkov
Publikováno v:
NeuroImage, Vol 235, Iss , Pp 118017- (2021)
Brain perturbation studies allow detailed causal inferences of behavioral and neural processes. Because the combination of brain perturbation methods and neural measurement techniques is inherently challenging, research in humans has predominantly fo
Externí odkaz:
https://doaj.org/article/982d8bb429264280b8b0dce07e0cbe49
Autor:
Lucija Rapan, Sean Froudist-Walsh, Meiqi Niu, Ting Xu, Thomas Funck, Karl Zilles, Nicola Palomero-Gallagher
Publikováno v:
NeuroImage, Vol 226, Iss , Pp 117574- (2021)
In the present study we reevaluated the parcellation scheme of the macaque frontal agranular cortex by implementing quantitative cytoarchitectonic and multireceptor analyses, with the purpose to integrate and reconcile the discrepancies between previ
Externí odkaz:
https://doaj.org/article/b43d649163254edbbd243c34461fb420
Autor:
Sean Froudist-Walsh, Philip GF Browning, James J Young, Kathy L Murphy, Rogier B Mars, Lazar Fleysher, Paula L Croxson
Publikováno v:
eLife, Vol 7 (2018)
The brain displays a remarkable ability to adapt following injury by altering its connections through neural plasticity. Many of the biological mechanisms that underlie plasticity are known, but there is little knowledge as to when, or where in the b
Externí odkaz:
https://doaj.org/article/d1d804515d8242c7958aadae52bdac08
Autor:
Sean Froudist-Walsh, Michael AP Bloomfield, Mattia Veronese, Jasmin Kroll, Vyacheslav R Karolis, Sameer Jauhar, Ilaria Bonoldi, Philip K McGuire, Shitij Kapur, Robin M Murray, Chiara Nosarti, Oliver Howes
Publikováno v:
eLife, Vol 6 (2017)
Perinatal brain injuries, including hippocampal lesions, cause lasting changes in dopamine function in rodents, but it is not known if this occurs in humans. We compared adults who were born very preterm with perinatal brain injury to those born very
Externí odkaz:
https://doaj.org/article/9ff67e0d97fb4ff1bff59270159f0d58
Autor:
Philip J. Brittain, Sean Froudist Walsh, Kie-Woo Nam, Vincent Giampietro, Vyacheslav Karolis, Robin M. Murray, Sagnik Bhattacharyya, Anastasia Kalpakidou, Chiara Nosarti
Publikováno v:
NeuroImage: Clinical, Vol 6, Iss C, Pp 54-63 (2014)
Very preterm birth (VPT;
Externí odkaz:
https://doaj.org/article/b11f9d16367c43a6a9219f52b1fea751
2482 Reward-based learning as a function of the severity of substance abuse risk in drug-naïve youth
Publikováno v:
Journal of Clinical and Translational Science, Vol 2, Pp 26-26 (2018)
OBJECTIVES/SPECIFIC AIMS: Deficits in reward-based learning have been shown in youth at risk for developing substance use disorders (SUD). Here, we investigated whether computational models can be used to more precisely delineate the additive effects
Externí odkaz:
https://doaj.org/article/b5f1c6cd0f554760ab215b64f4af8fe1
Autor:
Sean P. Walsh
Publikováno v:
Armed Forces & Society. 33:265-285
Although the Singapore Armed Forces is one of the most technologically advanced militaries in Southeast Asia, it suffers from a number of institutional weaknesses. Singapore's multiethnic but Chinese-dominated society and unique geographical and poli