Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sean P. Maxwell"'
Publikováno v:
The Lancet Planetary Health, Vol 4, Iss 11, Pp e497-e498 (2020)
Externí odkaz:
https://doaj.org/article/b49b6fc73dac41539ee12f3a2248f9e3
Publikováno v:
Global Ecology and Conservation, Vol 18, Iss , Pp - (2019)
Retaining and restoring habitat in areas that will remain climatically suitable through time is a key strategy for helping species' adapt to climate change - particularly in multi-use landscapes where species' find it difficult to track suitable clim
Externí odkaz:
https://doaj.org/article/f94380d357114daa845dee4a6dc3f171
Autor:
Andrzej J. Jakubowiak, Michael Kauffman, Sharon Shacham, Dilara McCauley, Stephanie J. Kraftson, Sean P. Maxwell, Dominik Dytfeld, Jagoda Jasielec, Samuel L. Volchenboum, Anoop Mayampurath, Malathi Kandarpa, Mattina M. Alonge, Shaun Rosebeck
Changes in mean tumor volume of all groups of mice treated with selinexor and carfilzomib, alone and in combination.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005bc07883661dab820c9799ea04f2c3
https://doi.org/10.1158/1535-7163.22503982.v1
https://doi.org/10.1158/1535-7163.22503982.v1
Autor:
Andrzej J. Jakubowiak, Michael Kauffman, Sharon Shacham, Dilara McCauley, Stephanie J. Kraftson, Sean P. Maxwell, Dominik Dytfeld, Jagoda Jasielec, Samuel L. Volchenboum, Anoop Mayampurath, Malathi Kandarpa, Mattina M. Alonge, Shaun Rosebeck
As in Figure 3E of the main text, MM1.S and RPMI 8226 cells were treated for 24 hours with caspase 9 inhibitor (LEHD; 50 µM), pan-caspase inhibitor, Q-VD-OPH, (VD; 25 µM), or caspase 10 inhibitor (AEVD; 25 µM) alone. Relative cell viability was de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b30944c4e6ebe23bce2b2a9f0ca5aa4
https://doi.org/10.1158/1535-7163.22503979
https://doi.org/10.1158/1535-7163.22503979
Autor:
Andrzej J. Jakubowiak, Michael Kauffman, Sharon Shacham, Dilara McCauley, Stephanie J. Kraftson, Sean P. Maxwell, Dominik Dytfeld, Jagoda Jasielec, Samuel L. Volchenboum, Anoop Mayampurath, Malathi Kandarpa, Mattina M. Alonge, Shaun Rosebeck
Exportin1 (XPO1; also known as chromosome maintenance region 1, or CRM1) controls nucleo-cytoplasmic transport of most tumor suppressors and is overexpressed in many cancers, including multiple myeloma, functionally impairing tumor suppressive functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612630839ff58fa3aa93ea158d444835
https://doi.org/10.1158/1535-7163.c.6537574.v1
https://doi.org/10.1158/1535-7163.c.6537574.v1
Autor:
Andrzej J. Jakubowiak, Michael Kauffman, Sharon Shacham, Dilara McCauley, Stephanie J. Kraftson, Sean P. Maxwell, Dominik Dytfeld, Jagoda Jasielec, Samuel L. Volchenboum, Anoop Mayampurath, Malathi Kandarpa, Mattina M. Alonge, Shaun Rosebeck
MM1.S cells were left untreated or treated with Selinexor and Carfilzomib (CFZ; 50 nm each) overnight. Cells were then processed as described for immunofluorescence microscopy using anti-Fas mouse monoclonal antibody and anti-p62 rabbit polyclonal an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::541eeb9470e3c6ef843a5729ff13b505
https://doi.org/10.1158/1535-7163.22503976.v1
https://doi.org/10.1158/1535-7163.22503976.v1
Autor:
Andrzej J. Jakubowiak, Michael Kauffman, Sharon Shacham, Dilara McCauley, Stephanie J. Kraftson, Sean P. Maxwell, Dominik Dytfeld, Jagoda Jasielec, Samuel L. Volchenboum, Anoop Mayampurath, Malathi Kandarpa, Mattina M. Alonge, Shaun Rosebeck
Plasma cells from patients that have failed on treatment regimens that have included proteasome inhibitors, immunomodulatory drugs, and DNA damaging agents were purified from fresh bone marrow aspirates and treated with selinexor and carfilzomib.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b13e63357da7aa3cb9d02217285c70
https://doi.org/10.1158/1535-7163.22503988
https://doi.org/10.1158/1535-7163.22503988
Autor:
Andrzej J. Jakubowiak, Michael Kauffman, Sharon Shacham, Dilara McCauley, Stephanie J. Kraftson, Sean P. Maxwell, Dominik Dytfeld, Jagoda Jasielec, Samuel L. Volchenboum, Anoop Mayampurath, Malathi Kandarpa, Mattina M. Alonge, Shaun Rosebeck
Additional details of antibodies, reagents, and methods used in this manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c535fd79016575bec65b71bdec8813fc
https://doi.org/10.1158/1535-7163.22503973.v1
https://doi.org/10.1158/1535-7163.22503973.v1
Autor:
Andrzej J. Jakubowiak, Michael Kauffman, Sharon Shacham, Dilara McCauley, Stephanie J. Kraftson, Sean P. Maxwell, Dominik Dytfeld, Jagoda Jasielec, Samuel L. Volchenboum, Anoop Mayampurath, Malathi Kandarpa, Mattina M. Alonge, Shaun Rosebeck
Western blot analysis of markers for autophagy and apoptosis in MM1.S cells treated for the indicated time with pan-caspase inhibitor.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6f4078ab84ceb6806b1e514a513be6
https://doi.org/10.1158/1535-7163.22503994
https://doi.org/10.1158/1535-7163.22503994
Autor:
Leif Saager, Baskar Rajala, Shubhangi Singh, Ruth Cassidy, Jill M. Mhyre, Thomas T. Klumpner, David M. Eckmann, Virgil Manica, Carlo Pancaro, Milo Engoren, Christie Vahabzadeh, Timur Dubovoy, Jasmine Purtell, Sean P Maxwell, Dana LaBuda
Publikováno v:
Obstetric Anesthesia Digest. 42:40-42
BACKGROUND While flexible epidural catheters reduce the risk of paresthesia and intravascular cannulation, they may be more challenging to advance beyond the tip of a Tuohy needle. This may increase placement time, number of attempts, and possibly co