Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Sean P. Hopkins"'
Autor:
Sean P. Hopkins, Megan C. Frost
Publikováno v:
Bioengineering, Vol 7, Iss 1, p 9 (2020)
Synthetic nitric oxide (NO)-donating materials have been shown to have many beneficial effects when incorporated into biomedical materials. When released in the correct dosage, NO has been shown to increase the biocompatibility of blood and tissue co
Externí odkaz:
https://doaj.org/article/b9bc4b13bb46496ebc9ef3ab188ec05d
Autor:
Sean P. Hopkins, Megan C. Frost
Publikováno v:
Bioengineering, Vol 5, Iss 3, p 72 (2018)
Polyvinyl chloride (PVC) is one of the most widely used polymers in medicine but has very poor biocompatibility when in contact with tissue or blood. To increase biocompatibility, controlled release of nitric oxide (NO) can be utilized to mitigate an
Externí odkaz:
https://doaj.org/article/5c265d607dc84736a71e8b1633f0f2f6
Publikováno v:
ACS Applied Materials & Interfaces. 14:11116-11123
Autor:
Megan Douglass, Ekrem Ozkan, Hitesh Handa, Sean P. Hopkins, Arnab Mondal, Rashmi Pandey, Priyadarshini Singha, James N. Warnock, Ryan Devine, Mark Garren, James Manuel
Publikováno v:
J Colloid Interface Sci
Addressing thrombosis and biofouling of indwelling medical devices within healthcare institutions is an ongoing problem. In this work, two types of ultra-low fouling surfaces (i.e., superhydrophobic and lubricant-infused slippery surfaces) were fabri
Publikováno v:
ACS Biomaterials Science & Engineering. 7:5279-5287
Attachment of a nitric oxide (NO) donor to an electrospun polymer has the potential to improve its proliferative and antimicrobial capabilities. This study presents the novel, covalent attachment of S-nitroso-N-acetylpenicillamine (SNAP) to polyacryl
Autor:
Arnab Mondal, Ekrem Ozkan, Ryan Devine, Hitesh Handa, Sean P. Hopkins, James N. Warnock, Mark Garren, Megan Douglass, Priyadarshini Singha, James Manuel
Publikováno v:
ACS Applied Materials & Interfaces. 12:51160-51173
Biofilm and thrombus formation on surfaces results in significant morbidity and mortality worldwide, which highlights the importance of the development of efficacious fouling-prevention approaches. In this work, novel highly robust and superhydrophob
Autor:
Nicole Tayag, Hitesh Handa, Megan Douglass, Elizabeth J. Brisbois, Dieu Thao Nguyen, Manjyot Kaur Chug, Morgan Ashcraft, Gina Kim, Mark Garren, Sean P. Hopkins
Publikováno v:
ACS applied materialsinterfaces.
Foreign body response and infection are two universal complications that occur with indwelling medical devices. In response, researchers have developed different antimicrobial and antifouling surface strategies to minimize bacterial colonization and
Autor:
Priyadarshini Singha, Megan Douglass, Arnab Mondal, Hitesh Handa, Elizabeth J. Brisbois, Martin Tran, Sean P. Hopkins
Publikováno v:
ACS Applied Materials & Interfaces. 11:34652-34662
Modern crises in implantable or indwelling blood-contacting medical devices are mainly due to the dual problems of infection and thrombogenicity. There is a paucity of biomaterials that can address both problems simultaneously through a singular plat
Autor:
Marcus J. Goudie, Megan Douglass, Jitendra Pant, Hitesh Handa, Shriya Pedaparthi, Sean P. Hopkins
Publikováno v:
ACS Biomater Sci Eng
Biological processes such as infection, angiogenesis, and fibroblast proliferation and migration need to be regulated for effective healing of a wound. Failing to do so can delay the overall wound healing and add to the suffering and healthcare cost.
Autor:
Priyadarshini Singha, Hitesh Handa, Megan Douglass, Marcus J. Goudie, Chad W. Schmiedt, Jitendra Pant, Ryan Devine, Sean P. Hopkins
Publikováno v:
ACS Appl Bio Mater
Devices used for extracorporeal circulation are met with two major medical concerns: thrombosis and infection. A device that allows for anticoagulant-free circulation while reducing risk of infection has yet to be developed. We report the use of a co