Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Sean P. Gunsten"'
Autor:
Hasan Farooq, Hannah P. Luehmann, Jeffrey R. Koenitzer, Gyu Seong Heo, Deborah H. Sultan, Devesha H. Kulkarni, Sean P. Gunsten, Rekha M. Sashti, Tao Huang, Amanda R. Keller, Kory J. Lavine, Jeffrey J. Atkinson, Laura M. Wingler, Yongjian Liu, Steven L. Brody
Publikováno v:
EBioMedicine, Vol 110, Iss , Pp 105431- (2024)
Summary: Background: Pulmonary fibrosis is a challenging clinical problem with lung pathology featuring immune cell infiltrates, fibroblast expansion, and matrix deposition. Molecular analysis of diseased lungs and preclinical models have uncovered C
Externí odkaz:
https://doaj.org/article/6ae5fd1a54164d1183633ab65d6b32ca
Autor:
Amjad Horani, Deepesh Kumar Gupta, Jian Xu, Huihui Xu, Lis del Carmen Puga-Molina, Celia M. Santi, Sruthi Ramagiri, Steven K. Brennan, Jiehong Pan, Jeffrey R. Koenitzer, Tao Huang, Rachael M. Hyland, Sean P. Gunsten, Shin-Cheng Tzeng, Jennifer M. Strahle, Pleasantine Mill, Moe R. Mahjoub, Susan K. Dutcher, Steven L. Brody
Publikováno v:
JCI Insight, Vol 8, Iss 11 (2023)
DNAAF5 is a dynein motor assembly factor associated with the autosomal heterogenic recessive condition of motile cilia, primary ciliary dyskinesia (PCD). The effects of allele heterozygosity on motile cilia function are unknown. We used CRISPR-Cas9 g
Externí odkaz:
https://doaj.org/article/a8958a20c7784cb38752182a624f9384
Autor:
Maritza Puray-Chavez, Nakyung Lee, Kasyap Tenneti, Yiqing Wang, Hung R. Vuong, Yating Liu, Amjad Horani, Tao Huang, Sean P. Gunsten, James B. Case, Wei Yang, Michael S. Diamond, Steven L. Brody, Joseph Dougherty, Sebla B. Kutluay
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) utilizes a number of strategies to modulate viral and host mRNA translation. Here, we used ribosome profiling in SARS-CoV-2-infected model cell lines and primary airway cells grown
Externí odkaz:
https://doaj.org/article/676d5a8350f546c5baeaa34cae4b2506
Publikováno v:
Physiological Reports, Vol 7, Iss 16, Pp n/a-n/a (2019)
Abstract To date, there are very limited noninvasive, regional assays of in vivo lung microstructure near the alveolar level. It has been suggested that x‐ray phase‐contrast enhanced imaging reveals information about the air volume of the lung; h
Externí odkaz:
https://doaj.org/article/8b2d0ac34448455994501ade7e50edaf
Autor:
Hannah Luehmann, Amber Salter, Benjamin D. Humphreys, Jeffrey J. Atkinson, Gyu Seong Heo, Yongjian Liu, Adrian Shifren, Cedric Mpoy, Christophe Combadière, Michelle Hoelscher, Sean P. Gunsten, Daniel Kreisel, Ethan C. Lee, Buck E. Rogers, Shuchi Guo, Tonya D. Russell, Jiehong Pan, Jeffrey R. Koenitzer, Delphine L. Chen, Derek E. Byers, Richard Laforest, Kory J. Lavine, Deborah H. Sultan, Tao Huang, Steven L. Brody, David S. Gierada, Robert J. Gropler
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 203:78-89
Rationale: Idiopathic pulmonary fibrosis (IPF) is a progressive inflammatory lung disease without effective molecular markers of disease activity or treatment responses. Monocyte and interstitial m...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9aba66372ad9a17457625ed13cfe080
https://doi.org/10.1164/rccm.202004-1132oc
https://doi.org/10.1164/rccm.202004-1132oc
Autor:
Shuchi Guo, Tonya D. Russell, Christophe Combadière, Derek E. Byers, Benjamin D. Humphreys, Jeffrey R. Koenitzer, Kory J. Lavine, Hannah Luehmann, Jiehong Pan, Adrian Shifren, Gyu Seong Heo, Amber Salter, David S. Gierada, Ethan C. Lee, Sean P. Gunsten, Robert J. Gropler, Daniel Kreisel, Jeffrey J. Atkinson, Michelle Hoelscher, Deborah H. Sultan, Tao Huang, Steven L. Brody, Richard Laforest, Yongjian Liu, Cedric Mpoy, Delphine L. Chen, Buck E. Rogers
Idiopathic pulmonary fibrosis (IPF) is a progressive, inflammatory lung disease that is monitored clinically by measures of lung function, without effective molecular markers of disease activity or therapeutic efficacy. Lung immune cells active in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b309dae1fbae679b094449221cf2581c
https://doi.org/10.1101/2020.03.04.960179
https://doi.org/10.1101/2020.03.04.960179
Autor:
Steven L. Brody, Karen L. Wooley, Mahmoud Elsabahy, Sarosh Khan, Amandine Noel, Sean P. Gunsten, Yannick P. Borguet
Publikováno v:
Biomacromolecules
To expand the range of functional polymer materials to include fully hydrolytically degradable systems that bear bioinspired phosphorus-containing linkages both along the backbone and as cationic side chain moieties for packaging and delivery of nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b723430d421e3dd2b00932c9f465667f
https://doi.org/10.1021/acs.biomac.8b00069
https://doi.org/10.1021/acs.biomac.8b00069
Autor:
Hannah Luehmann, Jeffrey J. Atkinson, Christophe Combadière, Deborah H. Sultan, T. Scott Blackwell, Jiehong Pan, Derek E. Byers, Steven L. Brody, Robert J. Gropler, Yongfeng Zhao, Sean P. Gunsten, Michael J. Holtzman, Yongjian Liu, Zachary Bollermann-Nowlis, Daniel Kreisel
Publikováno v:
Radiology. 283:758-768
Purpose To characterize a chemokine receptor type 2 (CCR2)-binding peptide adapted for use as a positron emission tomography (PET) radiotracer for noninvasive detection of lung inflammation in a mouse model of lung injury and in human tissues from su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257048a966a9ea897cf6a7313a3bcf4a
https://doi.org/10.1148/radiol.2016161409
https://doi.org/10.1148/radiol.2016161409
Autor:
Richard Laforest, Sean P. Gunsten, Michelle Hoelscher, Steven L. Brody, Delphine L. Chen, Derek E. Byers, Jiehong Pan, Y. Liu, Adrian Shifren, Jeffrey J. Atkinson, Deborah H. Sultan, Sally W. Schwarz, Hannah Luehmann, Gyu Seong Heo, Tonya D. Russell
Publikováno v:
D103. IDIOPATHIC INTERSTITIAL PNEUMONIAs: NATURAL HISTORY AND PROGNOSIS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::535484f1e67017435affe954c7775357
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7135
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7135
Autor:
Michelle Elvington, Lina Ma, Steven L. Brody, Hrishikesh S. Kulkarni, Sean P. Gunsten, John P. Atkinson, Xiaobo Wu
Publikováno v:
A61. EPITHELIAL BIOLOGY.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80b77f2e981b65f8be839f5379cd0961
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2133
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2133