Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Sean P Kennelly"'
Publikováno v:
BMC Neurology, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Over 55 million adults are living with dementia globally, which is projected to reach 157 million by 2050. Mild cognitive impairment (MCI), a syndrome of memory impairment with intact activities of daily living, may precede dement
Externí odkaz:
https://doaj.org/article/bbb019cecba14b0780e0ccba6136d92f
Autor:
Eimear Connolly, Shane Lyons, Cliona O’Farrelly, Graham Knight, Antoinette O’Connor, Adam H Dyer, Sean P Kennelly, Emily Killeen, Christine Gaffney, Helena Dolphin, Laura Morrison, Gavin Sedgwick, Aoife McFeely, Conal Gallagher, Naomi Davey, Conor Young, Ruth Ennis, Cathy McHale, Jasmine Joseph, Emmet Kelly, Nollaig M Bourke, Aoife Fallon, Sean O’Dowd
Publikováno v:
BMJ Open, Vol 13, Iss 12 (2023)
Introduction Alzheimer’s disease and other dementias affect >50 million individuals globally and are characterised by broad clinical and biological heterogeneity. Cohort and biobank studies have played a critical role in advancing the understanding
Externí odkaz:
https://doaj.org/article/0170f17c49d84fd19fc343b814ad8a68
Autor:
Zhengtao Hu, Tomas Ondrejcak, Pengpeng Yu, Yangyang Zhang, Yin Yang, Igor Klyubin, Sean P Kennelly, Michael J Rowan, Neng-Wei Hu
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 6, Pp 1213-1219 (2023)
Cognitive decline in Alzheimer’s disease correlates with the extent of tau pathology, in particular tau hyperphosphorylation that initially appears in the transentorhinal and related regions of the brain including the hippocampus. Recent evidence i
Externí odkaz:
https://doaj.org/article/0a9ffba41e18447cbef73f89a346a903
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285529 (2023)
BackgroundIn addition to the clear cardiovascular benefit, there has been renewed interest in the potential of statins in the prevention of cognitive impairment and dementia in older adults. However, whether ongoing statin use can delay cognitive dec
Externí odkaz:
https://doaj.org/article/b2bd3f353dac4d388c9970b0e35d7bb9
Publikováno v:
BMC Geriatrics, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background With the evolving knowledge on hearing as a potentially modifiable mid-life risk factor for dementia, identification of people at risk becomes increasingly important. People with mild cognitive impairment (MCI) presenting to speci
Externí odkaz:
https://doaj.org/article/4272a47f89cd473ab782fbc00674d41e
Autor:
Catherine Waldron, Joan Cahill, Sam Cromie, Tim Delaney, Sean P. Kennelly, Joshua M. Pevnick, Tamasine Grimes
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 21, Iss 1, Pp 1-17 (2021)
Abstract Background Medication reconciliation (MedRec), a process to reduce medication error at care transitions, is labour- and resource-intensive and time-consuming. Use of Personal Electronic Records of Medications (PERMs) in health information sy
Externí odkaz:
https://doaj.org/article/1ed4d0d7d6394ae29bc40fdb3768794a
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The vagus nerve is the longest nerve in the human body, providing afferent information about visceral sensation, integrity and somatic sensations to the CNS via brainstem nuclei to subcortical and cortical structures. Its efferent arm influences GI m
Externí odkaz:
https://doaj.org/article/8eb74becccc24f268698df9230888350
Publikováno v:
BMC Geriatrics, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Previous evidence suggests that slower gait speed is longitudinally associated with cognitive impairment, dementia and falls in older adults. Despite this, the longitudinal relationship between gait speed, cognition and falls in t
Externí odkaz:
https://doaj.org/article/66997f25611746c4b3112df79d1b90cc
Autor:
Pieter M. R. Herings, Adam H. Dyer, Sean P. Kennelly, Sean Reid, Isabelle Killane, Louise McKenna, Nollaig M. Bourke, Conor P. Woods, Desmond O’Neill, James Gibney, Richard B. Reilly
Publikováno v:
Sensors, Vol 22, Iss 15, p 5710 (2022)
Type 2 Diabetes Mellitus (T2DM) in midlife is associated with a greater risk of dementia in later life. Both gait speed and spatiotemporal gait characteristics have been associated with later cognitive decline in community-dwelling older adults. Thus
Externí odkaz:
https://doaj.org/article/7ed7546e4d974debad4e434247f6ac74
Autor:
Adam H. Dyer, Aoife Fallon, Claire Noonan, Helena Dolphin, Cliona O’Farrelly, Nollaig M. Bourke, Desmond O’Neill, Sean P. Kennelly
Publikováno v:
Journal of the American Medical Directors Association. 23:1590-1602
Older adults in nursing homes are at greatest risk of morbidity and mortality from SARS-CoV-2 infection. Nursing home residents constituted one-third to more than half of all deaths during the early waves of the COVID-19 pandemic. Following this, wid