Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sean P Gilmore"'
Autor:
Steven Hoang-Phou, Sukumar Pal, Anatoli Slepenkin, Abisola Abisoye-Ogunniyun, Yuliang Zhang, Sean F. Gilmore, Megan L. Shelby, Feliza A. Bourguet, Mariam V. Mohagheghi, Aleksandr Noy, Amy Rasley, Luis M. de la Maza, Matthew A. Coleman
Publikováno v:
Vaccines, Vol 12, Iss 10, p 1134 (2024)
Background:Chlamydia trachomatis is the most prevalent bacterial sexually transmitted pathogen in humans worldwide. Since chlamydial infection is largely asymptomatic with the potential for serious complications, a preventative vaccine is likely the
Externí odkaz:
https://doaj.org/article/be1c1bfa971e4e1c9f5a37fd0c53218d
Autor:
Kevin B. Weyant, Ayomide Oloyede, Sukumar Pal, Julie Liao, Mariela Rivera-De Jesus, Thapakorn Jaroentomeechai, Tyler D. Moeller, Steven Hoang-Phou, Sean F. Gilmore, Riya Singh, Daniel C. Pan, David Putnam, Christopher Locher, Luis M. de la Maza, Matthew A. Coleman, Matthew P. DeLisa
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Antigen display on outer membrane vesicles (OMVs) can be difficult to control and highly variable. Here, the authors describe a universal approach called AvidVax for linking biotinylated antigens to the exterior of OMVs and enabling rapid vaccine ass
Externí odkaz:
https://doaj.org/article/780bda2f571b451c977ae3d7dffe1457
Autor:
Nicholas R. Hum, Aimy Sebastian, Kelly A. Martin, Naiomy D. Rios-Arce, Sean F. Gilmore, David M. Gravano, Elizabeth K. Wheeler, Matthew A. Coleman, Gabriela G. Loots
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Due to lack of targetable receptors and intertumoral heterogeneity, triple negative breast cancer (TNBC) remains particularly difficult to treat. Doxorubicin (DOX) is typically used as nonselective neoadjuvant chemotherapy, but the diversity of treat
Externí odkaz:
https://doaj.org/article/c68fb0a68f6b4394a52c6b409b8dbd81
Autor:
Hung K. Doan, Viviane N. Ngassam, Sean F. Gilmore, Robin Tecon, Atul N. Parikh, Johan H. J. Leveau
Publikováno v:
Phytobiomes Journal, Vol 4, Iss 3, Pp 268-280 (2020)
To study the impact of lateral variation in surface topography on the microbial colonization of plant leaves, we used a two-step casting process to generate topomimetic “replicasts” in polydimethylsiloxane which faithfully resembled leaf surface
Externí odkaz:
https://doaj.org/article/3d7800d0bd7e40119014c741f051a48d
Autor:
Sean P. Gilmore, Stephen P. Lillington, Charles H. Haitjema, Randall de Groot, Michelle A. O'Malley
Publikováno v:
Synthetic and Systems Biotechnology, Vol 5, Iss 1, Pp 23-32 (2020)
Cellulosomes are synthesized by anaerobic bacteria and fungi to degrade lignocellulose via synergistic action of multiple enzymes fused to a protein scaffold. Through templating key protein domains (cohesin and dockerin), designer cellulosomes have b
Externí odkaz:
https://doaj.org/article/7a6faace2ac945d1a68098c2cb97b0bf
Autor:
Abisola Abisoye-Ogunniyan, Isabella M. Carrano, Dina R. Weilhammer, Sean F. Gilmore, Nicholas O. Fischer, Sukumar Pal, Luis M. de la Maza, Matthew A. Coleman, Amy Rasley
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
A worldwide estimate of over one million STIs are acquired daily and there is a desperate need for effective preventive as well as therapeutic measures to curtail this global health burden. Vaccines have been the most effective means for the control
Externí odkaz:
https://doaj.org/article/0fdef6d619294b57b153251ba39f8257
Autor:
Stephen P. Lillington, William Chrisler, Charles H. Haitjema, Sean P. Gilmore, Chuck R. Smallwood, Vaithiyalingam Shutthanandan, James E. Evans, Michelle A. O’Malley
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Anaerobic fungi ( Neocallimastigomycota
Externí odkaz:
https://doaj.org/article/5a22d0a96188484e90648e67bb868c34
Autor:
Dina R. Weilhammer, Alexis D. Dunkle, Tyler Boone, Sean F. Gilmore, Mark Khemmani, Sandra K. G. Peters, Paul D. Hoeprich, Nicholas O. Fischer, Craig D. Blanchette, Adam Driks, Amy Rasley
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Subunit vaccines are theoretically safe and easy to manufacture but require effective adjuvants and delivery systems to yield protective immunity, particularly at critical mucosal sites such as the lung. We investigated nanolipoprotein particles (NLP
Externí odkaz:
https://doaj.org/article/ca91e8ee57e54aeda6984465ee70cda7
Autor:
John K. Henske, Sean P. Gilmore, Doriv Knop, Francis J. Cunningham, Jessica A. Sexton, Chuck R. Smallwood, Vaithiyalingam Shutthanandan, James E. Evans, Michael K. Theodorou, Michelle A. O’Malley
Publikováno v:
Biotechnology for Biofuels, Vol 10, Iss 1, Pp 1-12 (2017)
Abstract Anaerobic gut fungi are the primary colonizers of plant material in the rumen microbiome, but are poorly studied due to a lack of characterized isolates. While most genera of gut fungi form extensive rhizoidal networks, which likely particip
Externí odkaz:
https://doaj.org/article/f5f62fcb56204de7a060ebda12eb6dff
Autor:
Delia F. Tifrea, Wei He, Sukumar Pal, Angela C. Evans, Sean F. Gilmore, Nicholas O. Fischer, Amy Rasley, Matthew A. Coleman, Luis M. de la Maza
Publikováno v:
Vaccines, Vol 9, Iss 7, p 755 (2021)
Chlamydia trachomatis is a sexually transmitted bacterium that infects over 130 million individuals worldwide annually. To implement a vaccine, we developed a cell-free co-translational system to express the Chlamydia muridarum major outer membrane p
Externí odkaz:
https://doaj.org/article/f51779adbaa644d184c15c06e7d33201