Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Sean P Dineen"'
Autor:
Christina L Roland, Kristi D Lynn, Jason E Toombs, Sean P Dineen, D Gomika Udugamasooriya, Rolf A Brekken
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7669 (2009)
The effect of blocking VEGF activity in solid tumors extends beyond inhibition of angiogenesis. However, no studies have compared the effectiveness of mechanistically different anti-VEGF inhibitors with respect to changes in tumor growth and alterati
Externí odkaz:
https://doaj.org/article/1f8ba5d37820475c9124a92a94922d4e
Autor:
Andrew J. Sinnamon, Michelle Savoldy, Rutika Mehta, Sean P. Dineen, Luis R. Peña, Gregory Y. Lauwers, Jose M. Pimiento
Publikováno v:
Annals of Surgical Oncology. 30:3580-3589
Autor:
Meagan Read, Benjamin D. Powers, Jose M. Pimiento, Danielle Laskowitz, Erin Mihelic, Iman Imanirad, Sophie Dessureault, Seth Felder, Sean P. Dineen
Publikováno v:
Annals of Surgical Oncology. 29:6980-6987
Malignant small bowel obstruction (mSBO) is a common consequence of advanced malignancies. Surgical consultation is common, however data on the outcomes following an operation are lacking. We investigated a specific operative approach-intestinal bypa
Autor:
Rolf A. Brekken, Jason B. Fleming, Carlton C. Barnett, Adam W. Beck, David S. Shames, James P. Sullivan, Andrew F. Miller, Shane E. Holloway, Kristi D. Lynn, Sean P. Dineen
Macrophages are an abundant inflammatory cell type in the tumor microenvironment that can contribute to tumor growth and metastasis. Macrophage recruitment into tumors is mediated by multiple cytokines, including vascular endothelial growth factor (V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f45ef1dcba6a7d75b06ca7fd89fa5e97
https://doi.org/10.1158/0008-5472.c.6497619
https://doi.org/10.1158/0008-5472.c.6497619
Autor:
Rolf A. Brekken, Jason B. Fleming, Carlton C. Barnett, Adam W. Beck, David S. Shames, James P. Sullivan, Andrew F. Miller, Shane E. Holloway, Kristi D. Lynn, Sean P. Dineen
Supplementary Figure 1 from Vascular Endothelial Growth Factor Receptor 2 Mediates Macrophage Infiltration into Orthotopic Pancreatic Tumors in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff2279db85e6902270362bfc1318dcb
https://doi.org/10.1158/0008-5472.22374867.v1
https://doi.org/10.1158/0008-5472.22374867.v1
Autor:
Rolf A. Brekken, James B. Lorens, Michael T. Dellinger, David Micklem, Sean P. Dineen, Miao Wang, Jason E. Toombs, Renate Ranaweera, Tone Sandal, Gry Haaland, Noah Sorrelle, Kathleen F. Ludwig, Amanda Kirane
Supplementary Tables S1-S2. Metastatic events in preclinical models of PDA (S1); Warfarin enhances the activity of gemcitabine in an Axl-dependent manner (S2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f51f7f62631108f61ea5f307de4091
https://doi.org/10.1158/0008-5472.22405361.v1
https://doi.org/10.1158/0008-5472.22405361.v1
Autor:
Rolf A. Brekken, James B. Lorens, Michael T. Dellinger, David Micklem, Sean P. Dineen, Miao Wang, Jason E. Toombs, Renate Ranaweera, Tone Sandal, Gry Haaland, Noah Sorrelle, Kathleen F. Ludwig, Amanda Kirane
Supplementary Figures S1-S6. Axl is required for the growth of Mia PaCa-2 tumors (S1); Characterization of 10C9 (S2); Warfarin inhibits autocrine activation of Axl in pancreatic tumor cells (S3); In vivo warfarin effects (S4); Maintenance of mesenchy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3811e238c2eb5002e9c3bdaf3e2302ed
https://doi.org/10.1158/0008-5472.22405367
https://doi.org/10.1158/0008-5472.22405367
Autor:
Rolf A. Brekken, James B. Lorens, Michael T. Dellinger, David Micklem, Sean P. Dineen, Miao Wang, Jason E. Toombs, Renate Ranaweera, Tone Sandal, Gry Haaland, Noah Sorrelle, Kathleen F. Ludwig, Amanda Kirane
Repurposing “old” drugs can facilitate rapid clinical translation but necessitates novel mechanistic insight. Warfarin, a vitamin K “antagonist” used clinically for the prevention of thrombosis for more than 50 years, has been shown to have a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d564c7a77f2cd47e20a363fe4fd21ed
https://doi.org/10.1158/0008-5472.c.6506816
https://doi.org/10.1158/0008-5472.c.6506816
Autor:
Rolf A. Brekken, John D. Minna, Noelle Williams, Haizhou Sun, Nabeel Bardeesy, Puja Gupta, Jason E. Toombs, Juliet G. Carbon, Rachel Greer, Christina L. Roland, Sean P. Dineen
Supplementary Figures 1-2, Tables 1-2 from Smac Mimetic Increases Chemotherapy Response and Improves Survival in Mice with Pancreatic Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::385ab78fcef9c05f2ee2d1e591e9593e
https://doi.org/10.1158/0008-5472.22387332.v1
https://doi.org/10.1158/0008-5472.22387332.v1
Autor:
Rolf A. Brekken, Jason B. Fleming, Carlton C. Barnett, Adam W. Beck, David S. Shames, James P. Sullivan, Andrew F. Miller, Shane E. Holloway, Kristi D. Lynn, Sean P. Dineen
Supplementary Figure 2 from Vascular Endothelial Growth Factor Receptor 2 Mediates Macrophage Infiltration into Orthotopic Pancreatic Tumors in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9bd11671179becb40bde5f48a5cd0e
https://doi.org/10.1158/0008-5472.22374864.v1
https://doi.org/10.1158/0008-5472.22374864.v1