Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Sean P Curtis"'
Autor:
Ke Hao, Yohan Bossé, David C Nickle, Peter D Paré, Dirkje S Postma, Michel Laviolette, Andrew Sandford, Tillie L Hackett, Denise Daley, James C Hogg, W Mark Elliott, Christian Couture, Maxime Lamontagne, Corry-Anke Brandsma, Maarten van den Berge, Gerard Koppelman, Alise S Reicin, Donald W Nicholson, Vladislav Malkov, Jonathan M Derry, Christine Suver, Jeffrey A Tsou, Amit Kulkarni, Chunsheng Zhang, Rupert Vessey, Greg J Opiteck, Sean P Curtis, Wim Timens, Don D Sin
Publikováno v:
PLoS Genetics, Vol 8, Iss 11, p e1003029 (2012)
Genome-wide association studies (GWAS) have identified loci reproducibly associated with pulmonary diseases; however, the molecular mechanism underlying these associations are largely unknown. The objectives of this study were to discover genetic var
Externí odkaz:
https://doaj.org/article/6259f2c8ff324226a4a1dc7021fe8b98
Autor:
Cindy L J Weinstein, Paula Sliwinska-Stanczyk, Tomas Hála, Marina Stanislav, Anjela Tzontcheva, Ruji Yao, Yuliya Berd, Sean P Curtis, George Philip
Publikováno v:
Rheumatology.
Objectives The GO-BACK study was designed to evaluate the efficacy and safety of golimumab (GLM) treatment withdrawal in adults with non-radiographic axial spondyloarthritis (nr-axSpA) who demonstrate inactive disease during a 10-month open-label (OL
Autor:
Maxime Dougados, G. Bergman, Sean P. Curtis, Désirée van der Heijde, Walter P. Maksymowych, Joachim Sieper, A. Tzontcheva, George Philip, Susan Huyck
Publikováno v:
Rheumatology (Oxford, England). 61(2)
Objectives We report the open-label extension (OLE) of the GO-AHEAD study evaluating the long-term efficacy and safety of golimumab (GLM) in patients with non-radiographic axial spondyloarthritis (nr-axSpA). Methods Patients [both GLM- and placebo (P
Autor:
Ke Hao, Yohan Bossé, David C. Nickle, Peter D. Paré, Dirkje S. Postma, Michel Laviolette, Andrew Sandford, Tillie L. Hackett, Denise Daley, James C. Hogg, W. Mark Elliott, Christian Couture, Maxime Lamontagne, Corry-Anke Brandsma, Maarten van den Berge, Gerard Koppelman, Alise S. Reicin, Donald W. Nicholson, Vladislav Malkov, Jonathan M. Derry, Christine Suver, Jeffrey A. Tsou, Amit Kulkarni, Chunsheng Zhang, Rupert Vessey, Greg J. Opiteck, Sean P. Curtis, Wim Timens, Don D. Sin
Publikováno v:
PLoS Genetics, Vol 8, Iss 12 (2012)
Externí odkaz:
https://doaj.org/article/1089411155cd4ffca18d2a904a27d910
Autor:
J. A. Boice, Joachim Sieper, Walter P. Maksymowych, Susan Huyck, A. Tzontcheva, Y. Berd, D. van der Heijde, Sean P. Curtis, H. H. Weng, G. Bergman, Maxime Dougados, B. B. Scott
Publikováno v:
Arthritis & Rheumatology (Hoboken, N.j.)
Axial spondyloarthritis (SpA) is a chronic inflammatory rheumatic disease characterized by inflammation of the sacroiliac (SI) joints and spine 1, 2. Patients with axial SpA experience chronic back pain and spinal stiffness as well as a reduction in
Autor:
Nora Franceschini, Yen Pei C. Chang, Susan Kirkland, Aravinda Chakravarti, Alice Stanton, Erik P A Van Iperen, Ilja M. Nolte, Jonathan A. Shaffer, Christopher P. Nelson, Aeilko H. Zwinderman, G. Kees Hovingh, Paul I.W. de Bakker, Christian Gieger, Shen Haiqing, John M. C. Connell, Xiaofeng Zhu, Patricia B. Munroe, Thomas S. Price, Eric Boerwinkle, Deepak L. Bhatt, Santhi K. Ganesh, Anna F. Dominiczak, Caitrin W. McDonough, Harold Snieder, Vinicius Tragante, Albertine J. Oldehinkel, Eoin O'Brien, Barbara E.K. Klein, Alexander P. Reiner, Mary E. Fischer, N. Charlotte Onland-Moret, Kate Witkowska, Christopher Newton-Cheh, Andrew D. Johnson, Laura Steele, Lynda M. Rose, Li Zhang, Erin N. Smith, Mark J. Caulfield, Sharon B. Wyatt, Morris Brown, Martin D. Tobin, Christian Delles, Gail P. Jarvik, Tom R. Gaunt, Hans L. Hillege, Steffi Maiwald, Nilesh J. Samani, Wolfgang Koenig, Konrad J. Karczewski, Julie A. Johnson, Brenda W.J.H. Penninx, Matthijs F.L. Meijs, Judith M. Vonk, Yvonne T. van der Schouw, Daniel I. Chasman, John Barnard, J. Hunter Young, Paul M. Ridker, Sean P. Curtis, Marten H. Hofker, Yan Gong, Jeffrey R. O'Connell, Barbara Thorand, Garret A. FitzGerald, Daichi Shimbo, Sonia Shah, Martin Farrall, Ronald P. Stolk, John G. Gums, Amber L. Beitelshees, Juan P. Casas, Pim van der Harst, Daniel Seung Kim, Peter S. Sever, André G. Uitterlinden, Michael Snyder, Brendan J. Keating, Susan Redline, Muredach P. Reilly, Michael V. Holmes, Maciej Tomaszewski, Daniel J. Rader, Sarah S. Murray, Myriam Fornage, Walter Palmas, Karina W. Davidson, Connie R. Bezzina, Gerald S. Berenson, Toby Johnson, Afshin Parsa, Cornelia M. van Duijn, Kandice Kottke-Marchant, Winfried März, Thomas Illig, W M Monique Verschuren, Aaron Isaacs, Matthew B. Lanktree, Amber A. Burt, Hugh Watkins, Daniel Levy, Hakon Hakonarson, Ramachandran S. Vasan, Johannes M.I.H. Gho, Nathan Pankratz, Sandosh Padmanabhan, Michael R. Barnes, Anuj Goel, Berta Almoguera, Xiuqing Guo, Peter J. van der Most, Ronald Klein, Mieke D. Trip, James S. Pankow, George Davey-Smith, Eric E. Schadt, Indrani Halder, Irene Mateo Leach, Meena Kumari, Claire E. Hastie, John J.P. Kastelein, Caroline O. L. Wong, Clara C. Elbers, Folkert W. Asselbergs, Wei Guo, Marcus E. Kleber, Karen J. Cruickshanks, Pieter A. Doevendans, Jane E. Ranchalis, Yun Li, Olle Melander, Jens Baumert, Ron T. Gansevoort, Rhonda M. Cooper-DeHoff, Mary Pettinger, Cisca Wijmenga
Publikováno v:
American Journal of Human Genetics, 94(3), 349-360. Cell Press
Tragante, V, Barnes, M R, Ganesh, S K, Lanktree, M B, Guo, W, Franceschini, N, Smith, E N, Johnson, T, Holmes, M V, Padmanabhan, S, Karczewski, K J, Almoguera, B, Barnard, J, Baumert, J, Chang, Y P C, Elbers, C C, Farrall, M, Fischer, M E, Gaunt, T R, Gho, J M I H, Gieger, C, Goel, A, Gong, Y, Isaacs, A, Kleber, M E, Leach, I M, McDonough, C W, Meijs, M F L, Melander, O, Nelson, C P, Nolte, I M, Pankratz, N, Price, T S, Shaffer, J, Shah, S, Tomaszewski, M, van der Most, P J, van Iperen, E P A, Vonk, J M, Witkowska, K, Wong, C O L, Zhang, L, Beitelshees, A L, Berenson, G S, Bhatt, D L, Brown, M, Burt, A, Cooper-DeHoff, R M, Connell, J M, Cruickshanks, K J, Curtis, S P, Davey-Smith, G, Delles, C, Gansevoort, R T, Guo, X Q, Haiqing, S, Hastie, C E, Hofker, M H, Hovingh, G K, Kim, D S, Kirkland, S A, Klein, B E, Klein, R, Li, Y R, Maiwald, S, Newton-Cheh, C, O'Brien, E T, Onland-Moret, N C, Palmas, W, Parsa, A, Penninx, B W, Pettinger, M, Vasan, R S, Ranchalis, J E, Ridker, P M, Rose, L M, Sever, P, Shimbo, D, Steele, L, Stolk, R P, Thorand, B, Trip, M D, van Duijn, C M, Verschuren, W M, Wijmenga, C, Wyatt, S, Young, J H, Zwinderman, A H, Bezzina, C R, Boerwinkle, E, Casas, J P, Caulfield, M J, Chakravarti, A, Chasman, D I, Davidson, K W, Doevendans, P A, Dominiczak, A F, FitzGerald, G A, Gums, J G, Munroe, P B & Keating, B J 2014, ' Gene-centric Meta-analysis in 87,736 Individuals of European Ancestry Identifies Multiple Blood-Pressure-Related Loci ', American journal of human genetics, vol. 94, no. 3, pp. 349-360 . https://doi.org/10.1016/j.ajhg.2013.12.016
Tragante, V, Barnes, M R, Ganesh, S K, Lanktree, M B, Guo, W, Franceschini, N, Smith, E N, Johnson, T, Holmes, M V, Padmanabhan, S, Karczewski, K J, Almoguera, B, Barnard, J, Baumert, J, Chang, Y P C, Elbers, C C, Farrall, M, Fischer, M E, Gaunt, T R, Gho, J M I H, Gieger, C, Goel, A, Gong, Y, Isaacs, A, Kleber, M E, Leach, I M, McDonough, C W, Meijs, M F L, Melander, O, Nelson, C P, Nolte, I M, Pankratz, N, Price, T S, Shaffer, J, Shah, S, Tomaszewski, M, van der Most, P J, van Iperen, E P A, Vonk, J M, Witkowska, K, Wong, C O L, Zhang, L, Beitelshees, A L, Berenson, G S, Bhatt, D L, Brown, M, Burt, A, Cooper-DeHoff, R M, Connell, J M, Cruickshanks, K J, Curtis, S P, Davey-Smith, G, Delles, C, Gansevoort, R T, Guo, X Q, Haiqing, S, Hastie, C E, Hofker, M H, Hovingh, G K, Kim, D S, Kirkland, S A, Klein, B E, Klein, R, Li, Y R, Maiwald, S, Newton-Cheh, C, O'Brien, E T, Onland-Moret, N C, Palmas, W, Parsa, A, Penninx, B W, Pettinger, M, Vasan, R S, Ranchalis, J E, Ridker, P M, Rose, L M, Sever, P, Shimbo, D, Steele, L, Stolk, R P, Thorand, B, Trip, M D, van Duijn, C M, Verschuren, W M, Wijmenga, C, Wyatt, S, Young, J H, Zwinderman, A H, Bezzina, C R, Boerwinkle, E, Casas, J P, Caulfield, M J, Chakravarti, A, Chasman, D I, Davidson, K W, Doevendans, P A, Dominiczak, A F, FitzGerald, G A, Gums, J G, Munroe, P B & Keating, B J 2014, ' Gene-centric Meta-analysis in 87,736 Individuals of European Ancestry Identifies Multiple Blood-Pressure-Related Loci ', American Journal of Human Genetics, vol. 94, no. 3, pp. 349-360 . https://doi.org/10.1016/j.ajhg.2013.12.016
Europe PubMed Central
American journal of human genetics, 94(3), 349-360. Cell Press
American Journal of Human Genetics, 94(3), 349-60. Cell Press
American Journal of Human Genetics, 94(3), 349-360. CELL PRESS
Tragante, V, Barnes, M R, Ganesh, S K, Lanktree, M B, Guo, W, Franceschini, N, Smith, E N, Johnson, T, Holmes, M V, Padmanabhan, S, Karczewski, K J, Almoguera, B, Barnard, J, Baumert, J, Chang, Y P C, Elbers, C C, Farrall, M, Fischer, M E, Gaunt, T R, Gho, J M I H, Gieger, C, Goel, A, Gong, Y, Isaacs, A, Kleber, M E, Leach, I M, McDonough, C W, Meijs, M F L, Melander, O, Nelson, C P, Nolte, I M, Pankratz, N, Price, T S, Shaffer, J, Shah, S, Tomaszewski, M, van der Most, P J, van Iperen, E P A, Vonk, J M, Witkowska, K, Wong, C O L, Zhang, L, Beitelshees, A L, Berenson, G S, Bhatt, D L, Brown, M, Burt, A, Cooper-DeHoff, R M, Connell, J M, Cruickshanks, K J, Curtis, S P, Davey-Smith, G, Delles, C, Gansevoort, R T, Guo, X Q, Haiqing, S, Hastie, C E, Hofker, M H, Hovingh, G K, Kim, D S, Kirkland, S A, Klein, B E, Klein, R, Li, Y R, Maiwald, S, Newton-Cheh, C, O'Brien, E T, Onland-Moret, N C, Palmas, W, Parsa, A, Penninx, B W, Pettinger, M, Vasan, R S, Ranchalis, J E, Ridker, P M, Rose, L M, Sever, P, Shimbo, D, Steele, L, Stolk, R P, Thorand, B, Trip, M D, van Duijn, C M, Verschuren, W M, Wijmenga, C, Wyatt, S, Young, J H, Zwinderman, A H, Bezzina, C R, Boerwinkle, E, Casas, J P, Caulfield, M J, Chakravarti, A, Chasman, D I, Davidson, K W, Doevendans, P A, Dominiczak, A F, FitzGerald, G A, Gums, J G, Munroe, P B & Keating, B J 2014, ' Gene-centric Meta-analysis in 87,736 Individuals of European Ancestry Identifies Multiple Blood-Pressure-Related Loci ', American journal of human genetics, vol. 94, no. 3, pp. 349-360 . https://doi.org/10.1016/j.ajhg.2013.12.016
Tragante, V, Barnes, M R, Ganesh, S K, Lanktree, M B, Guo, W, Franceschini, N, Smith, E N, Johnson, T, Holmes, M V, Padmanabhan, S, Karczewski, K J, Almoguera, B, Barnard, J, Baumert, J, Chang, Y P C, Elbers, C C, Farrall, M, Fischer, M E, Gaunt, T R, Gho, J M I H, Gieger, C, Goel, A, Gong, Y, Isaacs, A, Kleber, M E, Leach, I M, McDonough, C W, Meijs, M F L, Melander, O, Nelson, C P, Nolte, I M, Pankratz, N, Price, T S, Shaffer, J, Shah, S, Tomaszewski, M, van der Most, P J, van Iperen, E P A, Vonk, J M, Witkowska, K, Wong, C O L, Zhang, L, Beitelshees, A L, Berenson, G S, Bhatt, D L, Brown, M, Burt, A, Cooper-DeHoff, R M, Connell, J M, Cruickshanks, K J, Curtis, S P, Davey-Smith, G, Delles, C, Gansevoort, R T, Guo, X Q, Haiqing, S, Hastie, C E, Hofker, M H, Hovingh, G K, Kim, D S, Kirkland, S A, Klein, B E, Klein, R, Li, Y R, Maiwald, S, Newton-Cheh, C, O'Brien, E T, Onland-Moret, N C, Palmas, W, Parsa, A, Penninx, B W, Pettinger, M, Vasan, R S, Ranchalis, J E, Ridker, P M, Rose, L M, Sever, P, Shimbo, D, Steele, L, Stolk, R P, Thorand, B, Trip, M D, van Duijn, C M, Verschuren, W M, Wijmenga, C, Wyatt, S, Young, J H, Zwinderman, A H, Bezzina, C R, Boerwinkle, E, Casas, J P, Caulfield, M J, Chakravarti, A, Chasman, D I, Davidson, K W, Doevendans, P A, Dominiczak, A F, FitzGerald, G A, Gums, J G, Munroe, P B & Keating, B J 2014, ' Gene-centric Meta-analysis in 87,736 Individuals of European Ancestry Identifies Multiple Blood-Pressure-Related Loci ', American Journal of Human Genetics, vol. 94, no. 3, pp. 349-360 . https://doi.org/10.1016/j.ajhg.2013.12.016
Europe PubMed Central
American journal of human genetics, 94(3), 349-360. Cell Press
American Journal of Human Genetics, 94(3), 349-60. Cell Press
American Journal of Human Genetics, 94(3), 349-360. CELL PRESS
Blood pressure (BP) is a heritable risk factor for cardiovascular disease. To investigate genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial pressure (MAP), and pulse pressure (PP), we genotyped ∼50,000 SNPs in up to 87,
Autor:
Braxton D. Mitchell, Wei Chen, Wei Guo, Joseph F. Polak, Wolfgang Koenig, Jonathan A. Shaffer, Christian Gieger, Thomas Illig, Abdullah Kutlar, Jessica van Setten, Matthew B. Lanktree, Pieter A. Doevendans, Nicholas J. Schork, Cisca Wijmenga, G. Kees Hovingh, Christopher Newton-Cheh, Daniel Levy, Marten H. Hofker, Eric E. Schadt, Folkert W. Asselbergs, Nicole Soranzo, Sathanur R. Srinivasan, Olle Mellander, Daniel J. Rader, Roy L. Silverstein, David Duggan, Lynda M. Rose, Ron T. Gansevoort, Cliona Molony, André G. Uitterlinden, Li Zhang, Gerald S. Berenson, John Barnard, Vasan S. Ramachandran, Paul M. Ridker, Toby Johnson, Cornelia M. van Duijn, J. Hunter Young, Martin Farrall, Willem H. Ouwehand, Muredach P. Reilly, Tom S. Price, Sean P. Curtis, Brendan J. Keating, John G. Gums, Deepak L. Bhatt, Ilja M. Nolte, Barbara Thorand, Georg Ehret, Hans L. Hillege, Julie A. Johnson, Bernhard R. Winkelmann, Andrea Z. LaCroix, Patricia B. Munroe, Vinicius Tragante, Alan R. Shuldiner, Mieke D. Trip, Karina W. Davidson, Kandice Kottke-Marchant, Hubert Scharnag, Andrew D. Johnson, Ben Burkley, Clement E. Furlong, Winfried März, Yvonne T. van der Schouw, Yen Pei C. Chang, Hakon Hakonarson, Erin N. Smith, Aaron Isaacs, Eric Boerwinkle, Albertine J. Oldehinkel, Haiqing Shen, Richard R. Fabsitz, Alice Stanton, Steffi Maiwald, Matthijs F.L. Meijs, Johannes M.I.H. Gho, Yan Gong, Herman A. Taylor, Mary E. Fischer, Jeffery R. O'Connell, Santhi K. Ganesh, Rhonda M. Cooper-DeHoff, Ervin R. Fox, Albert W. Dreisbach, Brenda W.J.H. Penninx, Susan Kirkland, Caitrin W. McDonough, Nora Franceschini, Daniel I. Chasman, Amber L. Beitelshees, Carl J. Pepine, Tom R. Gaunt, Gurunathan Murugesan, Pim van der Harst, Irene Mateo Leach, Aravinda Chakravarti, Mary Pettinger, Gail P. Jarvik, Marcus E. Kleber, Paul I.W. de Bakker, Myriam Fornage, Mark J. Caulfield, Amber A. Burt, Judith M. Vonk, Sandosh Padmanabhan, Jane E. Ranchalis, Sonia Shah, Berta Almoguera Castillo, Erik P A Van Iperen, Jolanda M. A. Boer, Kiang Liu, Ronald P. Stolk, Garret A. FitzGerald, Yun Li, Rainer Malik, Jens Baumert, Peter J. van der Most, W. M. Monique Verschuren, Bernhard O. Boehm, Clara C. Elbers, Xiaofeng Zhu, Harold Snieder, N. Charlotte Onland-Moret, Honghuang Lin, Taimour Y. Langaee, Ramakrishnan Rajagopalan, John J.P. Kastelein, Nilesh J. Samani, Daichi Shimbo, Susan Redline, Sarah S. Murray, Alexander P. Reiner, Sharon B. Wyatt, Walter Palmas, Yiran Guo
Publikováno v:
Human Molecular Genetics; Vol 22
Ganesh, S K, Tragante, V, Guo, W, Guo, Y R, Lanktree, M B, Smith, E N, Johnson, T, Castillo, B A, Barnard, J, Baumert, J, Chang, Y P C, Elbers, C C, Farrall, M, Fischer, M E, Franceschini, N, Gaunt, T R, Gho, J M I H, Gieger, C, Gong, Y, Isaacs, A, Kleber, M E, Leach, I M, McDonough, C W, Meijs, M F L, Mellander, O, Molony, C M, Nolte, I M, Padmanabhan, S, Price, T S, Rajagopalan, R, Shaffer, J, Shah, S, Shen, H Q, Soranzo, N, van der Most, P J, van Iperen, E P A, Van Setten, J A, Vonk, J M, Zhang, L, Beitelshees, A L, Berenson, G S, Bhatt, D L, Boer, J M A, Boerwinkle, E, Burkley, B, Burt, A, Chakravarti, A, Chen, W, Cooper-DeHoff, R M, Curtis, S P, Dreisbach, A, Duggan, D, Ehret, G B, Fabsitz, R R, Fornage, M, Fox, E, Furlong, C E, Gansevoort, R T, Hofker, M H, Hovingh, G K, Kirkland, S A, Kottke-Marchant, K, Kutlar, A, LaCroix, A Z, Langaee, T Y, Li, Y R, Lin, H H, Liu, K, Maiwald, S, Malik, R, Murugesan, G, Newton-Cheh, C, OConnell, J R, Onland-Moret, N C, Ouwehand, W H, Palmas, W, Penninx, B W J H, Pepine, C J, Pettinger, M, Polak, J F, Ramachandran, V S, Ranchalis, J, Redline, S, Ridker, P M, Rose, L M, Scharnag, H, Schork, N J, Shimbo, D, Shuldiner, A R, Srinivasan, S R, Stolk, R P, Taylor, H A, Thorand, B, Trip, M D, van Duijn, C M, Verschuren, W M, Wijmenga, C, Winkelmann, B R, Wyatt, S, Keating, B J & Asselbergs, F W 2013, ' Loci influencing blood pressure identified using a cardiovascular gene-centric array ', Human Molecular Genetics, vol. 22, no. 8, pp. 1663-1678 . https://doi.org/10.1093/hmg/dds555
Europe PubMed Central
Human Molecular Genetics, 22(8), 1663-78. Oxford University Press
Human Molecular Genetics, 22(8), 1663-1678. Oxford University Press
Human Molecular Genetics, Vol. 22, No 8 (2013) pp. 1663-78
Human molecular genetics, 22(8), 1663-1678. Oxford University Press
Human Molecular Genetics
Ganesh, S K, Tragante, V, Guo, W, Guo, Y R, Lanktree, M B, Smith, E N, Johnson, T, Castillo, B A, Barnard, J, Baumert, J, Chang, Y P C, Elbers, C C, Farrall, M, Fischer, M E, Franceschini, N, Gaunt, T R, Gho, J M I H, Gieger, C, Gong, Y, Isaacs, A, Kleber, M E, Leach, I M, McDonough, C W, Meijs, M F L, Mellander, O, Molony, C M, Nolte, I M, Padmanabhan, S, Price, T S, Rajagopalan, R, Shaffer, J, Shah, S, Shen, H Q, Soranzo, N, van der Most, P J, van Iperen, E P A, Van Setten, J A, Vonk, J M, Zhang, L, Beitelshees, A L, Berenson, G S, Bhatt, D L, Boer, J M A, Boerwinkle, E, Burkley, B, Burt, A, Chakravarti, A, Chen, W, Cooper-DeHoff, R M, Curtis, S P, Dreisbach, A, Duggan, D, Ehret, G B, Fabsitz, R R, Fornage, M, Fox, E, Furlong, C E, Gansevoort, R T, Hofker, M H, Hovingh, G K, Kirkland, S A, Kottke-Marchant, K, Kutlar, A, LaCroix, A Z, Langaee, T Y, Li, Y R, Lin, H H, Liu, K, Maiwald, S, Malik, R, Murugesan, G, Newton-Cheh, C, OConnell, J R, Onland-Moret, N C, Ouwehand, W H, Palmas, W, Penninx, B W J H, Pepine, C J, Pettinger, M, Polak, J F, Ramachandran, V S, Ranchalis, J, Redline, S, Ridker, P M, Rose, L M, Scharnag, H, Schork, N J, Shimbo, D, Shuldiner, A R, Srinivasan, S R, Stolk, R P, Taylor, H A, Thorand, B, Trip, M D, van Duijn, C M, Verschuren, W M, Wijmenga, C, Winkelmann, B R, Wyatt, S, Keating, B J & Asselbergs, F W 2013, ' Loci influencing blood pressure identified using a cardiovascular gene-centric array ', Human Molecular Genetics, vol. 22, no. 8, pp. 1663-1678 . https://doi.org/10.1093/hmg/dds555
Europe PubMed Central
Human Molecular Genetics, 22(8), 1663-78. Oxford University Press
Human Molecular Genetics, 22(8), 1663-1678. Oxford University Press
Human Molecular Genetics, Vol. 22, No 8 (2013) pp. 1663-78
Human molecular genetics, 22(8), 1663-1678. Oxford University Press
Human Molecular Genetics
Blood pressure (BP) is a heritable determinant of risk for cardiovascular disease (CVD). To investigate genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial pressure (MAP) and pulse pressure (PP), we genotyped ∼50 000 sing
Autor:
Henry Krum, Loren Laine, Sean P. Curtis, Gary Swergold, Amarjot Kaur, Hongwei Wang, Paul M. Peloso, Christopher P. Cannon, D. Craig Brater, Matthew R. Weir, Steven S. Smugar, Arnold R. Gammaitoni
Publikováno v:
Cardiovascular Therapeutics. 30:342-350
SUMMARY Introduction: The increased thrombotic cardiovascular (CV) risk in trials of cyclo- oxygenase-2 (COX-2) inhibitors versus placebo, and the apparent similar risk with nons- teroidal antiinflammatory drugs (NSAIDs), may be related to their pote
Autor:
Charles F. Contant, David A. Morrow, Christopher P. Cannon, Fang Ren, Loren Laine, Sean P. Curtis, Kay Brune, Christian T. Ruff, Peter Jarolim, Amarjot Kaur
Publikováno v:
The Journal of Rheumatology. 38:1071-1078
Objective.Patients with arthritis frequently are at increased risk for future cardiovascular (CV) events. We investigated the performance of the cardiac biomarkers N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high sensitivity C-reactive
Publikováno v:
Alimentary Pharmacology & Therapeutics. 32:1240-1248
Aliment Pharmacol Ther 2010; 32: 1240–1248 Summary Background Nonsteroidal anti-inflammatory drugs (NSAID)-related GI effects vary based on patient characteristics. Aims To assess risk factors for NSAID-associated upper GI clinical events and dyspe