Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Sean P, Troth"'
Autor:
Dawn M. Zimmerman, Emily Hardgrove, Sara Sullivan, Stephanie Mitchell, Eddy Kambale, Julius Nziza, Benard Ssebide, Chantal Shalukoma, Mike Cranfield, Pranav S. Pandit, Sean P. Troth, Taylor Callicrate, Philip Miller, Kirsten Gilardi, Robert C. Lacy
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Ebola virus is highly lethal for great apes. Estimated mortality rates up to 98% have reduced the global gorilla population by approximately one-third. As mountain gorillas (Gorilla beringei beringei) are endangered, with just over 1000 indi
Externí odkaz:
https://doaj.org/article/d7c3b9ea38c649e3b7edd9c526845854
Autor:
Igor Morozov, Thomas P. Monath, David A. Meekins, Jessie D. Trujillo, Sun-Young Sunwoo, Kinga Urbaniak, In Joong Kim, Sanjeev K. Narayanan, Sabarish V. Indran, Wenjun Ma, William C. Wilson, Cassandra O'Connor, Sheri Dubey, Sean P. Troth, Beth-Ann Coller, Richard Nichols, Brian K. Martin, Heinz Feldmann, Juergen A. Richt
Publikováno v:
Emerging Microbes and Infections, Vol 10, Iss 1, Pp 651-663 (2021)
The recent impact of Ebola virus disease (EVD) on public health in Africa clearly demonstrates the need for a safe and efficacious vaccine to control outbreaks and mitigate its threat to global health. ERVEBO® is an effective recombinant Vesicular S
Externí odkaz:
https://doaj.org/article/76a36bca1a3948bfb5561339b098a75b
Autor:
Thomas P. Monath, Patricia E. Fast, Kayvon Modjarrad, David K. Clarke, Brian K. Martin, Joan Fusco, Richard Nichols, D. Gray Heppner, Jakub K. Simon, Sheri Dubey, Sean P. Troth, Jayanthi Wolf, Vidisha Singh, Beth-Ann Coller, James S. Robertson
Publikováno v:
Vaccine: X, Vol 1, Iss , Pp - (2019)
The Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG) was formed to evaluate the safety and characteristics of live, recombinant viral vector vaccines. A recent publication by the V3SWG described live, attenuated, recombinant
Externí odkaz:
https://doaj.org/article/b07b8cb0eee148b0870ad44a4db1f958
Autor:
Jakub K. Simon, Jayanthi J. Wolf, Sheri Dubey, Sean P. Troth, Risat Jannat, Matthew T. Onorato
Publikováno v:
Antiviral Discovery for Highly Pathogenic Emerging Viruses ISBN: 9781788015646
Drug Discovery
Drug Discovery
The requirements to gain licensure and manufacture a vaccine for human use are multifaceted, costly, and time-consuming. Despite the expenditure and challenges, preventative vaccines are considered one of the most cost-effective and efficient means t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22d847c5e631cc8d88daf6a90280003a
https://doi.org/10.1039/9781788016858-00121
https://doi.org/10.1039/9781788016858-00121
Autor:
Ronnie Chamanza, Niraj Tripathi, Bindu Bennet, Marie-France Perron Lepage, Jayanthi J. Wolf, Karissa Adkins, Keith Nelson, Sean P. Troth, Sebastien Laurent, Rani S. Sellers
Publikováno v:
Toxicologic Pathology. 48:257-276
The design and execution of toxicology studies supporting vaccine development have some unique considerations relative to those supporting traditional small molecules and biologics. A working group of the Society of Toxicologic Pathology Scientific a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f370501659f4588114afd54c2a8cafc
https://doi.org/10.1177/0192623319875085
https://doi.org/10.1177/0192623319875085
Publikováno v:
Seminars in Nephrology. 39:202-214
Acute kidney injury continues to be a common problem and there continues to be a medical need for sensitive translational biomarkers for clinical monitoring. The past decade has yielded unprecedented progress in fundamental research into novel kidney
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963639c19be732c6ce807d060d2193e7
https://doi.org/10.1016/j.semnephrol.2018.12.008
https://doi.org/10.1016/j.semnephrol.2018.12.008
Publikováno v:
Seminars in Nephrology. 39:120-131
The kidney's role as a major route of metabolism and clearance of xenobiotics and its ability to concentrate the glomerular filtrate make it particularly vulnerable to drug-induced toxicity. Improving kidney safety is an active area of research and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa5bc83bda52183eeff79c052792c66
https://doi.org/10.1016/j.semnephrol.2018.12.002
https://doi.org/10.1016/j.semnephrol.2018.12.002
Autor:
George R. Painter, Jay A. Grobler, Joan R. Butterton, Daria J. Hazuda, Patricia A. Escobar, Sean P. Troth, Carisa Stadlman DeAnda
Publikováno v:
The Journal of Infectious Diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4457458ced5a3dc3e017bdc3eb2b8af
http://europepmc.org/articles/PMC8344688
http://europepmc.org/articles/PMC8344688
Autor:
Sean P. Troth, Heinz Feldmann, Sabarish V. Indran, Sheri Dubey, Sanjeev Narayanan, Juergen A. Richt, Wenjun Ma, Cassandra O'Connor, Jessie D. Trujillo, Richard A. Nichols, Brian K. Martin, Sun Young Sunwoo, Beth-Ann Coller, William C. Wilson, Igor Morozov, Thomas P. Monath, In-Joong Kim, Kinga Urbaniak, David A. Meekins
Publikováno v:
Emerging Microbes & Infections
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The recent impact of Ebola virus disease (EVD) on public health in Africa clearly demonstrates the need for a safe and efficacious vaccine to control outbreaks and mitigate its threat to global health. ERVEBO® is an effective recombinant Vesicular S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e23b3d63e410bbd76c8dfb9759754c6e
Publikováno v:
Toxicologic pathology. 48(5)
To date, there has been very little published data evaluating the performance of novel urinary kidney biomarkers in nonhuman primates (NHPs). To assess the biomarker performance and characterize the corresponding histomorphologic patterns of tubular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010759ec4ac355eb7dcf4292328ba910
https://pubmed.ncbi.nlm.nih.gov/32633702
https://pubmed.ncbi.nlm.nih.gov/32633702