Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sean M. Santos"'
Autor:
Sean M. Santos, John L. Hartman
Publikováno v:
Cancer & Metabolism, Vol 7, Iss 1, Pp 1-42 (2019)
Abstract Background The influence of the Warburg phenomenon on chemotherapy response is unknown. Saccharomyces cerevisiae mimics the Warburg effect, repressing respiration in the presence of adequate glucose. Yeast phenomic experiments were conducted
Externí odkaz:
https://doaj.org/article/46470821611343129a0af5265755d22e
Autor:
Y. Mao, Kathryn E. Oliver, Jeong S. Hong, Mert Icyuz, Sean M. Santos, John L. Hartman, A. Rab, Eric J. Sorscher
Publikováno v:
Journal of Cystic Fibrosis. 20:S291-S292
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f26804deaed96e146dcfa140152d0d3d
https://doi.org/10.1016/s1569-1993(21)02037-3
https://doi.org/10.1016/s1569-1993(21)02037-3
Autor:
Joline Hartheimer, Samantha Laflin, Cosby Burnet, Daniel L. Smith, Sean M. Santos, Audrie Broadway, John L. Hartman, John W. Rodgers
Publikováno v:
GeroScience
Yeast cells survive in stationary phase culture by entering quiescence, which is measured by colony-forming capacity upon nutrient re-exposure. Yeast chronological lifespan (CLS) studies, employing the comprehensive collection of gene knockout strain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc834afcedba256c32d8214f97e2c46
https://europepmc.org/articles/PMC8110628/
https://europepmc.org/articles/PMC8110628/
Autor:
Elisa Enriquez-Hesles, Margaret B. Wierman, Ryan D. Fine, Sean M. Santos, Daniel L. Smith, Nazif Maqani, James R. Bain, Agata Kalita, Matthew D. Hirschey, Matthew D. Sutcliffe, Jeffrey S. Smith, John L. Hartman, Kevin A. Janes, Michael J. Muehlbauer
Publikováno v:
The Journal of Biological Chemistry
Caloric restriction (CR) improves health span and life span of organisms ranging from yeast to mammals. Understanding the mechanisms involved will uncover future interventions for aging-associated diseases. In budding yeast, Saccharomyces cerevisiae,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c7c1c9266dc964189fb3241f15bac4
https://pubmed.ncbi.nlm.nih.gov/33243834
https://pubmed.ncbi.nlm.nih.gov/33243834
Autor:
Daniel L. Smith, Kevin A. Janes, Elisa Enriquez-Hesles, John L. Hartman, Sean M. Santos, Ryan D. Fine, Jeffrey S. Smith, Matthew D. Sutcliffe, James R. Bain, Nazif Maqani, Margaret B. Wierman, Agata Kalita, Michael J. Muehlbauer, Matthew D. Hirschey
Caloric restriction (CR) improves healthspan and lifespan of organisms ranging from yeast to mammals. Understanding the mechanisms involved will uncover future interventions for aging associated diseases. In budding yeast,Saccharomyces cerevisiae, CR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdd2c699af9a62bc7a0139ea0dfcdb8f
https://doi.org/10.1101/2020.07.13.200493
https://doi.org/10.1101/2020.07.13.200493
Autor:
John W. Rodgers, Sean M. Santos, Audrie Broadway, Daniel L. Smith, Joline Hartheimer, John L. Hartman, Cosby Burnett, Samantha Laflin
Yeast cells survive in stationary phase culture by entering quiescence, which is measured by colony forming capacity upon nutrient re-exposure. Yeast chronological lifespan (CLS) studies, employing the comprehensive collection of gene knockout strain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0087eaf69e7676c491623be99a67a833
https://doi.org/10.1101/2020.05.25.114801
https://doi.org/10.1101/2020.05.25.114801
Autor:
Doreen William, Jingyu Guo, Ilya Pound, John W. Rodgers, Michael Niederweis, John L. Hartman, Mert Icyuz, Brett A. McKinney, Sean M. Santos
Publikováno v:
Genes, Vol 10, Iss 10, p 770 (2019)
Genes
Volume 10
Issue 10
Genes
Volume 10
Issue 10
Knowledge about synthetic lethality can be applied to enhance the efficacy of anticancer therapies in individual patients harboring genetic alterations in their cancer that specifically render it vulnerable. We investigated the potential for high-res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81937c50fc4c93a60664b4258e4298b4
Yeast Phenomics: An Experimental Approach for Modeling Gene Interaction Networks that Buffer Disease
Autor:
Darryl Alan Outlaw, John L. Hartman, Richard A. White, Najaf A. Shah, Sean M. Santos, John W. Rodgers, Dehua Tian, Chandler Stisher, Jingyu Guo
Publikováno v:
Genes
Volume 6
Issue 1
Pages 24-45
Genes, Vol 6, Iss 1, Pp 24-45 (2015)
Volume 6
Issue 1
Pages 24-45
Genes, Vol 6, Iss 1, Pp 24-45 (2015)
The genome project increased appreciation of genetic complexity underlying disease phenotypes: many genes contribute each phenotype and each gene contributes multiple phenotypes. The aspiration of predicting common disease in individuals has evolved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e425a18101fc5c74aca281e006715b
http://europepmc.org/articles/PMC4377832
http://europepmc.org/articles/PMC4377832