Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sean M. Raph"'
Kv beta complex facilitates exercise-induced augmentation of myocardial perfusion and cardiac growth
Autor:
Sean M. Raph, Ernesto Pena Calderin, Yibing Nong, Kenneth Brittian, Lauren Garrett, Deqing Zhang, Matthew A. Nystoriak
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
The oxygen sensitivity of voltage-gated potassium (Kv) channels regulates cardiovascular physiology. Members of the Kv1 family interact with intracellular Kvβ proteins, which exhibit aldo-keto reductase (AKR) activity and confer redox sensitivity to
Externí odkaz:
https://doaj.org/article/d0ae650d2e3b47aaa4bbddad5af440cf
Autor:
Marc M. Dwenger, Sean M. Raph, Michelle L. Reyzer, M. Lisa Manier, Daniel W. Riggs, Zachary B. Wohl, Vahagn Ohanyan, Gregory Mack,, Thomas Pucci, Joseph B. Moore, Bradford G. Hill, William M. Chilian, Richard M. Caprioli, Aruni Bhatnagar, Matthew A. Nystoriak
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Physiological matching of blood flow to the demand for oxygen by the heart is required for sustained cardiac health, yet the underlying mechanisms are obscure. Here, the authors report a key role for acute modifications to the redox state of intracel
Externí odkaz:
https://doaj.org/article/4aa8ba78bde7487dbf20db8be440e7ba
Publikováno v:
Cells, Vol 11, Iss 14, p 2230 (2022)
Excitable cells of the nervous and cardiovascular systems depend on an assortment of plasmalemmal potassium channels to control diverse cellular functions. Voltage-gated potassium (Kv) channels are central to the feedback control of membrane excitabi
Externí odkaz:
https://doaj.org/article/e6732b020bc94f0e9f3907c942e63eb0
Publikováno v:
The Journal of Physiology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25522eb9ca18c0cb71ad4e5ce863a244
https://doi.org/10.1113/jp284195
https://doi.org/10.1113/jp284195
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c3d3a7704584d2c43f676542eb27735
https://doi.org/10.1096/fasebj.2022.36.s1.r5993
https://doi.org/10.1096/fasebj.2022.36.s1.r5993
Publikováno v:
Chem Biol Interact
Voltage-gated potassium (Kv) channels play an essential role in the regulation of membrane excitability and thereby control physiological processes such as cardiac excitability, neural communication, muscle contraction, and hormone secretion. Members
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3884abfd3132972ea32f72fdd8ede346
https://doi.org/10.1016/j.cbi.2019.03.023
https://doi.org/10.1016/j.cbi.2019.03.023
Autor:
Thomas Pucci, Sean M. Raph, Gregory David Mack, Xuemei Hu, Matthew A. Nystoriak, Aruni Bhatnagar, Marc Dwenger, Joseph B. Moore, William M. Chilian, Vahagn Ohanyan
Publikováno v:
Circ Res
Rationale: Voltage-gated potassium (Kv) channels in vascular smooth muscle are essential for coupling myocardial blood flow (MBF) with the metabolic demand of the heart. These channels consist of a transmembrane pore domain that associates with auxil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957292fb13a0842094087f001827f227
https://pubmed.ncbi.nlm.nih.gov/33734818
https://pubmed.ncbi.nlm.nih.gov/33734818
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22d33f85c5bf3bf2738a0aac8a52397e
https://doi.org/10.1096/fasebj.2020.34.s1.07494
https://doi.org/10.1096/fasebj.2020.34.s1.07494