Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sean M. McGurran"'
Autor:
Jody L. Lutterman, Sean M. Mcgurran, Laxma G. Reddy, Kevin S. Gorski, Calin D. Dumitru, Elaine A. Egging, Kenneth E. Lipson, Melissa M. Piri, Gary W. Gullikson, Dave D. Johnson, Felicia R. Cochran, Mark A. Tomai, Mary A. Antonysamy, Joel Proksch
Publikováno v:
Cancer Immunology, Immunotherapy. 58:575-587
Innate immune stimulation with Toll-like receptor (TLR) agonists is a proposed modality for immunotherapy of melanoma. Here, a TLR7/8 agonist, 3M-011, was used effectively as a single systemic agent against disseminated mouse B16-F10 melanoma. The in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bdbe93f142191f83b42d1b7b4b788af
https://doi.org/10.1007/s00262-008-0581-7
https://doi.org/10.1007/s00262-008-0581-7
Publikováno v:
The Journal of Immunology. 177:155-161
The generation of tumor-specific T cells is hampered by the presentation of poorly immunogenic tumor-specific epitopes by the tumor. Here, we demonstrate that, although CD8+ T cells specific for the self/tumor Ag tyrosinase-related protein 2 (TRP2) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd50655dd69b5fa6d90384b2d44c5143
https://doi.org/10.4049/jimmunol.177.1.155
https://doi.org/10.4049/jimmunol.177.1.155
Autor:
John P. Vasilakos, Tony R. Riter, Randolph J. Noelle, Richard J. Barth, Ross M. Kedl, Christie L. Doxsee, Cory L. Ahonen, William F. Wade, Sean M. McGurran
Publikováno v:
The Journal of Experimental Medicine
Toll-like receptors are important in the activation of innate immunity, and CD40 is a molecule critical for many T and B cell responses. Whereas agonists for either pathway have been used as vaccine adjuvants, we show that a combination of Toll-like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436e4daaae92b5999d364a943bf526b3
http://europepmc.org/articles/PMC2212721
http://europepmc.org/articles/PMC2212721
Autor:
David M. Hammerbeck, Sean M. Mcgurran, David D. Johnson, Gary W. Gullikson, Ann M. Hupperts, Pam L. Radziszewski, Elaine A. Egging
Publikováno v:
Inflammation. 24:317-329
Representative glucocorticosteroids (GCS) and phosphodiesterase IV (PDE4) inhibitors were compared in several models of pulmonary inflammation ranging in severity. Lung tissue eosinophil peroxidase (EPO) levels rather than bronchoalveolar lavage flui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f41981ef3c1727d50b49306eafa45327
https://doi.org/10.1023/a:1007092830169
https://doi.org/10.1023/a:1007092830169