Výsledky vyhledávání - "Sean M. McGuire"

Demonstration of Baeyer-Villiger oxidation and the course of cyclization in bisfuran ring formation during aflatoxin B1 biosynthesis

Autor: Sean M. McGuire, Craig A. Townsend

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 3:653-656

The mechanism of tetrahydrobisfuran formation in aflatoxin B1 biosynthesis is defined in experiments that monitor the incorporation of molecular oxygen into an anthraquinone intermediate of the pathway in conjunction with cell-free reactions that com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::412ce94391b7d061f9ae801d2695b03c
https://doi.org/10.1016/s0960-894x(01)81247-6

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Purification and characterization of versicolorin B synthase from Aspergillus parasiticus. Catalysis of the stereodifferentiating cyclization in aflatoxin biosynthesis essential to DNA interaction

Autor: Craig A. Townsend, Sean M. McGuire, Jeffrey Cruz Silva, Eduard G. Casillas

Publikováno v: Biochemistry. 35(35)

The absolute configuration of the dihydrobisfuran ring system characteristic of aflatoxin B1 is essential to the covalent reaction of its metabolically activated form with double-stranded DNA. The biosynthesis of this potent mycotoxin proceeds throug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d972fb30752dee0dbaa4dd7fb33151d0
https://pubmed.ncbi.nlm.nih.gov/8784203

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Partitioning of tetrahydro- and dihydrobisfuran formation in aflatoxin biosynthesis defined by cell-free and direct incorporation experiments

Autor: Craig A. Townsend, Kollol Pal, Todd L. Graybill, Sean M. McGuire, Susan W. Brobst

Publikováno v: Journal of the American Chemical Society. 111:8308-8309

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f8593c6291e164f2e2a568bcf1a13fa
https://doi.org/10.1021/ja00203a058

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