Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sean M. Culbertson"'
Publikováno v:
Journal of Biological Chemistry. 278:38384-38394
The inhibition of post-Amadori advanced glycation end product (AGE) formation by three different classes of AGE inhibitors, carbonyl group traps, chelators, and radical-trapping antioxidants, challenge the current paradigms that: 1) AGE inhibitors wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f8a42f5909c2b389dfacee183f3d17c
https://doi.org/10.1074/jbc.m305099200
https://doi.org/10.1074/jbc.m305099200
Publikováno v:
Organic Letters. 5:2659-2662
[structure: see text] Pyridoxamine is known to be an effective inhibitor of both advanced glycation (AGE) and advanced lipoxidation (ALE) end products. The synthesis of a novel multifunctional AGE and ALE inhibitor, 6-dimethylaminopyridoxamine (dmaPM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ad95d977bac2cb7fb89f1be5807887
https://doi.org/10.1021/ol0348147
https://doi.org/10.1021/ol0348147
Publikováno v:
Chemical Research in Toxicology. 15:870-876
This work reports an estimate of the inhibition rate constant (k(inh)) for alpha-tocopherol (alpha-TOH) in low-density lipoproteins (LDL) based on cholesteryl linoleate hydroperoxide products formed during autoxidation of intact lipoproteins. The rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94a7403bb5587cf5df011595dee2898a
https://doi.org/10.1021/tx020012t
https://doi.org/10.1021/tx020012t
Autor:
Sean M. Culbertson and, Ned A. Porter
Publikováno v:
Journal of the American Chemical Society. 122:4032-4038
Lipid peroxidation studies often employ the use of azo initiators to produce a slow, steady source of free radicals, but the lack of initiators capable of efficiently generating radicals in lipid a...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91f7bb15c94c02f647d3285410ec463e
https://doi.org/10.1021/ja9934605
https://doi.org/10.1021/ja9934605
Autor:
Ned A. Porter, Sean M. Culbertson
Publikováno v:
Free Radical Research. 33:705-718
Lipid peroxidation studies often employ the use of azo initiators to produce a slow, steady source of free radicals, but the lack of initiators capable of efficiently generating radicals in lipid regions has created persistent problems in these inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8d66c66750dc0efad31ef5a65f8414
https://doi.org/10.1080/10715760000301231
https://doi.org/10.1080/10715760000301231
Autor:
Byeong Seon Jeong, Ned A. Porter, Tae-gyu Nam, Remigiusz A. Serwa, Derek A. Pratt, Christopher L. Rector, Luca Valgimigli, Sean M. Culbertson
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 16(47)
3-Pyridinols bearing amine substitution para to the hydroxylic moiety have previously been shown to inhibit lipid peroxidation more effectively than typical phenolic antioxidants, for example, α-tocopherol. We report here high-yielding, large-scale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b87c0085538e79eb6a64030347df71f
https://pubmed.ncbi.nlm.nih.gov/20967898
https://pubmed.ncbi.nlm.nih.gov/20967898
Publikováno v:
The Journal of biological chemistry. 278(40)
The inhibition of post-Amadori advanced glycation end product (AGE) formation by three different classes of AGE inhibitors, carbonyl group traps, chelators, and radical-trapping antioxidants, challenge the current paradigms that: 1) AGE inhibitors wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2383e28ffbba22c02a0ea8e81c6f867
https://pubmed.ncbi.nlm.nih.gov/12878609
https://pubmed.ncbi.nlm.nih.gov/12878609
Publikováno v:
Journal of the American Chemical Society. 123(37)
The antioxidant alpha-tocopherol (alpha-TOH) has been found to act as a pro-oxidant under many in vitro conditions. The observed tocopoherol-mediated peroxidation (TMP) is dependent on two primary factors. (1) Chain transfer: alpha-TO. radical reacts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a00440bedcd1ba380bbc1e18d58e7e64
https://pubmed.ncbi.nlm.nih.gov/11552801
https://pubmed.ncbi.nlm.nih.gov/11552801
Autor:
Antoni Kozlowski, Barbara Dietrich, Reinhard Stidl, Eva-Maria Muchitsch, Juergen Siekmann, Hans Peter Schwarz, Sean M. Culbertson, Mary J. Bossard, Hanspeter Rottensteiner, Chyung Cook, Xiaoming Shen, Tony Drew Vinson, Friedrich Scheiflinger, Hartmut J. Ehrlich, Peter Turecek
Publikováno v:
Blood. 118:4358-4358
Abstract 4358 Baxter and Nektar have developed BAX 855, a PEGylated variant of Baxter’s rFVIII product based on the ADVATE™ manufacturing process using Nektar’s polymer technology. The absorption, metabolism, distribution and excretion (ADME) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3dd1877a2d465499f6a10d904873b1c
https://doi.org/10.1182/blood.v118.21.4358.4358
https://doi.org/10.1182/blood.v118.21.4358.4358