Výsledky vyhledávání - "Sean M. Conrad"

A role for IgG immune complexes during infection with the intracellular pathogen Leishmania

Autor: David M. Mosser, Sean M. Conrad, Selma M. B. Jeronimo, Suzanne A. Miles, Renata G. Alves

Publikováno v: The Journal of Experimental Medicine

We examined the role of immunoglobulin (Ig)G antibodies in mediating host defense to the intracellular parasite, Leishmania. We show that IgG not only fails to provide protection against this intracellular pathogen, but it actually contributes to dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71040dd08b42230260cc383b42ada48
https://doi.org/10.1084/jem.20041470

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Monocyte subpopulations and their differentiation patterns during infection

Autor: Dalit Strauss-Ayali, David M. Mosser, Sean M. Conrad

Publikováno v: Journal of leukocyte biology. 82(2)

The term “monocyte” implies a single, homogenous population of cells with uniform physiology. Recent evidence from a number of laboratories indicates that it is likely that blood monocytes may consist of several subpopulations of cells, which dif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9078db445a6cfafd47df0361bcf84ee
https://pubmed.ncbi.nlm.nih.gov/17475785

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Reduced pathology following infection with transgenic Leishmania major expressing murine CD40 ligand

Autor: Ann E. Field, David M. Mosser, Sean M. Conrad, Sagie Wagage

Publikováno v: Infection and immunity. 75(6)

Leishmanization is the inoculation of liveLeishmaniainto the host to vaccinate against subsequent infections. This approach has been largely discontinued due to safety concerns. We have previously shown that combining CD40 ligand (CD40L) withLeishman

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8858ef7dd27c4537024f502d8e42d913
https://pubmed.ncbi.nlm.nih.gov/17403867

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Leishmania-Derived Murine Monocyte Chemoattractant Protein 1 Enhances the Recruitment of a Restrictive Population of CC Chemokine Receptor 2-Positive Macrophages▿

Autor: Dalit Strauss-Ayali, Matthias Mack, David M. Mosser, Sean M. Conrad, Ann E. Field

Transgenic Leishmania parasites that encode the murine chemokine monocyte chemoattractant protein 1 (MCP-1) were generated. These parasites transcribed MCP-1 mRNA and secreted MCP-1 protein. Infection of BALB/c, C57BL/6, or MCP-1 knockout (KO) mice w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5fa8873a1f4fce38b949c944533654
https://europepmc.org/articles/PMC1828528/

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