Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Sean M. Buchanan"'
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-13 (2021)
Abstract Growth differentiation factor 11 (GDF11) is a transforming factor-β superfamily member that functions as a negative regulator of neurogenesis during embryonic development. However, when recombinant GDF11 (rGDF11) is administered systemicall
Externí odkaz:
https://doaj.org/article/845c8c04bc9a45caa11403271aeb710e
Autor:
Sean M. Buchanan, Feodor D. Price, Alessandra Castiglioni, Amanda Wagner Gee, Joel Schneider, Mark N. Matyas, Monica Hayhurst, Mohammadsharif Tabebordbar, Amy J. Wagers, Lee L. Rubin
Publikováno v:
Skeletal Muscle, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Satellite cells are the canonical muscle stem cells that regenerate damaged skeletal muscle. Loss of function of these cells has been linked to reduced muscle repair capacity and compromised muscle health in acute muscle injury and congenita
Externí odkaz:
https://doaj.org/article/0d62174c7a004102b33478f2b3005ecb
Autor:
Methodios Ximerakis, Kristina M. Holton, Richard M. Giadone, Ceren Ozek, Monika Saxena, Samara Santiago, Xian Adiconis, Danielle Dionne, Lan Nguyen, Kavya M. Shah, Jill M. Goldstein, Caterina Gasperini, Ioannis A. Gampierakis, Scott L. Lipnick, Sean K. Simmons, Sean M. Buchanan, Amy J. Wagers, Aviv Regev, Joshua Z. Levin, Lee L. Rubin
Publikováno v:
Nature Aging. 3:327-345
Aging is a complex process involving transcriptomic changes associated with deterioration across multiple tissues and organs, including the brain. Recent studies using heterochronic parabiosis have shown that various aspects of aging-associated decli
Autor:
Methodios Ximerakis, Kristina M. Holton, Richard M. Giadone, Ceren Ozek, Monika Saxena, Samara Santiago, Xian Adiconis, Danielle Dionne, Lan Nguyen, Kavya M. Shah, Jill M. Goldstein, Caterina Gasperini, Scott L. Lipnick, Sean K. Simmons, Sean M. Buchanan, Amy J. Wagers, Aviv Regev, Joshua Z. Levin, Lee L. Rubin
Aging is a complex process involving transcriptomic changes associated with deterioration across multiple tissues and organs, including the brain. Recent studies using heterochronic parabiosis have shown that various aspects of aging-associated decli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faa15dde94ef8da6cad65bafb306b3bd
https://doi.org/10.1101/2022.01.27.477911
https://doi.org/10.1101/2022.01.27.477911
Publikováno v:
Molecular Brain
Molecular Brain, Vol 14, Iss 1, Pp 1-13 (2021)
Molecular Brain, Vol 14, Iss 1, Pp 1-13 (2021)
Growth differentiation factor 11 (GDF11) is a transforming factor-β superfamily member that functions as a negative regulator of neurogenesis during embryonic development. However, when recombinant GDF11 (rGDF11) is administered systemically in aged
Autor:
Ruth Isserlin, Lan Nguyen, Vincent L. Butty, Joshua Z. Levin, Xian Adiconis, Methodios Ximerakis, Brittany A Mayweather, Ceren Ozek, Lee L. Rubin, Sean M. Buchanan, Sean Simmons, Scott Lipnick, Stuart S. Levine, Zachary Niziolek, Danielle Dionne, Brendan T. Innes, Aviv Regev, Gary D. Bader
Publikováno v:
Nature Neuroscience. 22:1696-1708
The mammalian brain is complex, with multiple cell types performing a variety of diverse functions, but exactly how each cell type is affected in aging remains largely unknown. Here we performed a single-cell transcriptomic analysis of young and old
Autor:
Gerald Vinatier, Vincenzo G. Fiore, Edgar Buhl, Danielle C. Diaper, Benjamin L. de Bivort, Chenghao Chen, Raymond J. Dolan, Frank Hirth, Zoe N. Ludlow, Keita Endo, Yoshitsugu Adachi, Sheena Brown, James J L Hodge, Kei Ito, Nicholas J. Strausfeld, Stephan J. Sigrist, Daniel A. Solomon, Jean-René Martin, Alan Stepto, Katherine E. White, Dickon M. Humphrey, Sean M. Buchanan, Richard Faville, Ralf Stanewsky, Benjamin Kottler, Jonah Dearlove
Publikováno v:
BioRxiv
The insect central complex and vertebrate basal ganglia are forebrain centres involved in selection and maintenance of behavioural actions. However, little is known about the formation of the underlying circuits, or how they integrate sensory informa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2989c701ca55944611538ce5283e21
https://hal.archives-ouvertes.fr/hal-02413547
https://hal.archives-ouvertes.fr/hal-02413547
Autor:
Jolanta Idkowiak-Baldys, Sean M. Buchanan, Kathleen L. Pfaff, Lee L. Rubin, John W. Lyga, Uma Santhanam
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218035 (2019)
PLoS ONE
PLoS ONE
Growth differentiation factor 11 (GDF11) belongs to the TGF-β superfamily of proteins and is closely related to myostatin. Recent findings show that GDF11 has rejuvenating properties with pronounced effects on the cardiovascular system, brain, skele
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Aging is the biggest risk factor for several neurodegenerative diseases. Parabiosis experiments have established that old mouse brains are improved by exposure to young mouse blood. Previously, our lab showed that delivery of Growth Differentiation F
Autor:
Xian Adiconis, Stuart S. Levine, Brittany A Mayweather, Ruth Isserlin, Scott Lipnick, Vincent L. Butty, Lan Nguyen, Lee L. Rubin, Danielle Dionne, Methodios Ximerakis, Ceren Ozek, Sean M. Buchanan, Sean Simmons, Joshua Z. Levin, Brendan T. Innes, Zachary Niziolek, Aviv Regev, Gary D. Bader
The mammalian brain is complex, with multiple cell types performing a variety of diverse functions, but exactly how the brain is affected with aging remains largely unknown. Here we performed a single-cell transcriptomic analysis of young and old mou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c60c20399c61f2ce5f11971bb97f67