Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sean M. Biggs"'
Autor:
Eric R. Prossnitz, Larry A. Sklar, Anna Waller, Peter C. Simons, Sean M. Biggs, Bruce S. Edwards
Publikováno v:
Trends in Pharmacological Sciences. 25:663-669
Flow cytometers are well known for their ability to analyze and sort cells at high rates based on physiological responses and expression of protein markers. The potential for flow cytometry in G-protein-coupled receptor (GPCR) research, however, is l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5afe19c6a0dd79eddfe4155ce84b18bd
https://doi.org/10.1016/j.tips.2004.10.009
https://doi.org/10.1016/j.tips.2004.10.009
Autor:
Eric R. Prossnitz, Sean M. Biggs, Wei-Jen Tang, Anna Waller, Larry A. Sklar, Richard R. Neubig, Qing Guo, Daniel F. Cimino, Peter C. Simons, Terry D. Foutz
Publikováno v:
Journal of Biological Chemistry. 279:13514-13521
We developed a novel and generalized approach to investigate G protein-coupled receptor molecular assemblies. We solubilized a fusion protein consisting of the β2-adrenergic receptor and green fluorescent protein (GFP) for bead-based flow cytometric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca42c8ef4dc42046ab590c63d4efcfb9
https://doi.org/10.1074/jbc.m310306200
https://doi.org/10.1074/jbc.m310306200
Autor:
Marius Olah, Anna Waller, Susan M. Young, Sean M. Biggs, Larry A. Sklar, Bruce S. Edwards, Cristian Bologa, Peter C. Simons, Eric R. Prossnitz, Tudor I. Oprea
Publikováno v:
Pharmaceutical Sciences Encyclopedia ISBN: 9780470571224
This article describes the creation of a discovery team in an academic environment. The team is specifically structured to perform four integrated activities: characterizing membrane protein, formatting the materials for analysis of cell physiology a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0d7648815ef15c75b4194f31c8c2b30
https://doi.org/10.1002/9780470571224.pse006
https://doi.org/10.1002/9780470571224.pse006
Some Mechanistic Insights into GPCR Activation from Detergent‐Solubilized Ternary Complexes on Beads
Autor:
Peter C. Simons, Yang Wu, Eric R. Prossnitz, Sean M. Biggs, Tione Buranda, Larry A. Sklar, Anna Waller
Publikováno v:
Advances in Protein Chemistry ISBN: 9780120342884
The binding of full and partial agonist ligands (L) to G protein-coupled receptors (GPCRs) initiates the formation of ternary complexes with G proteins [ligand-receptor-G protein (LRG) complexes]. Cyclic ternary complex models are required to account
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15e77d5a4d156e048aaabff0c653390b
https://doi.org/10.1016/s0065-3233(07)74003-2
https://doi.org/10.1016/s0065-3233(07)74003-2
Autor:
Peter C, Simons, Sean M, Biggs, Anna, Waller, Terry, Foutz, Daniel F, Cimino, Qing, Guo, Richard R, Neubig, Wei-Jen, Tang, Eric R, Prossnitz, Larry A, Sklar
Publikováno v:
The Journal of biological chemistry. 279(14)
We developed a novel and generalized approach to investigate G protein-coupled receptor molecular assemblies. We solubilized a fusion protein consisting of the beta(2)-adrenergic receptor and green fluorescent protein (GFP) for bead-based flow cytome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bba66915e05c4c45b104b1bc4f74c91b
https://pubmed.ncbi.nlm.nih.gov/14726530
https://pubmed.ncbi.nlm.nih.gov/14726530