Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Sean M Buchanan"'
Autor:
Jolanta Idkowiak-Baldys, Uma Santhanam, Sean M Buchanan, Kathleen Lindahl Pfaff, Lee L Rubin, John Lyga
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218035 (2019)
Growth differentiation factor 11 (GDF11) belongs to the TGF-β superfamily of proteins and is closely related to myostatin. Recent findings show that GDF11 has rejuvenating properties with pronounced effects on the cardiovascular system, brain, skele
Externí odkaz:
https://doaj.org/article/ff73e527a734408e98fefb46675b6c53
Autor:
Sean M. Buchanan, Feodor D. Price, Alessandra Castiglioni, Amanda Wagner Gee, Joel Schneider, Mark N. Matyas, Monica Hayhurst, Mohammadsharif Tabebordbar, Amy J. Wagers, Lee L. Rubin
Publikováno v:
Skeletal Muscle, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Satellite cells are the canonical muscle stem cells that regenerate damaged skeletal muscle. Loss of function of these cells has been linked to reduced muscle repair capacity and compromised muscle health in acute muscle injury and congenita
Externí odkaz:
https://doaj.org/article/0d62174c7a004102b33478f2b3005ecb
Autor:
Methodios Ximerakis, Kristina M. Holton, Richard M. Giadone, Ceren Ozek, Monika Saxena, Samara Santiago, Xian Adiconis, Danielle Dionne, Lan Nguyen, Kavya M. Shah, Jill M. Goldstein, Caterina Gasperini, Ioannis A. Gampierakis, Scott L. Lipnick, Sean K. Simmons, Sean M. Buchanan, Amy J. Wagers, Aviv Regev, Joshua Z. Levin, Lee L. Rubin
Publikováno v:
Nature Aging. 3:327-345
Aging is a complex process involving transcriptomic changes associated with deterioration across multiple tissues and organs, including the brain. Recent studies using heterochronic parabiosis have shown that various aspects of aging-associated decli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8657f8805441eff3eb51264f9415b9f0
https://doi.org/10.1038/s43587-023-00373-6
https://doi.org/10.1038/s43587-023-00373-6
Autor:
Methodios Ximerakis, Kristina M. Holton, Richard M. Giadone, Ceren Ozek, Monika Saxena, Samara Santiago, Xian Adiconis, Danielle Dionne, Lan Nguyen, Kavya M. Shah, Jill M. Goldstein, Caterina Gasperini, Scott L. Lipnick, Sean K. Simmons, Sean M. Buchanan, Amy J. Wagers, Aviv Regev, Joshua Z. Levin, Lee L. Rubin
Aging is a complex process involving transcriptomic changes associated with deterioration across multiple tissues and organs, including the brain. Recent studies using heterochronic parabiosis have shown that various aspects of aging-associated decli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faa15dde94ef8da6cad65bafb306b3bd
https://doi.org/10.1101/2022.01.27.477911
https://doi.org/10.1101/2022.01.27.477911
Publikováno v:
Molecular Brain
Molecular Brain, Vol 14, Iss 1, Pp 1-13 (2021)
Molecular Brain, Vol 14, Iss 1, Pp 1-13 (2021)
Growth differentiation factor 11 (GDF11) is a transforming factor-β superfamily member that functions as a negative regulator of neurogenesis during embryonic development. However, when recombinant GDF11 (rGDF11) is administered systemically in aged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce0f5276f7ed5141e9e1ded2ac862c4b
http://europepmc.org/articles/PMC8422669
http://europepmc.org/articles/PMC8422669
Autor:
Ruth Isserlin, Lan Nguyen, Vincent L. Butty, Joshua Z. Levin, Xian Adiconis, Methodios Ximerakis, Brittany A Mayweather, Ceren Ozek, Lee L. Rubin, Sean M. Buchanan, Sean Simmons, Scott Lipnick, Stuart S. Levine, Zachary Niziolek, Danielle Dionne, Brendan T. Innes, Aviv Regev, Gary D. Bader
Publikováno v:
Nature Neuroscience. 22:1696-1708
The mammalian brain is complex, with multiple cell types performing a variety of diverse functions, but exactly how each cell type is affected in aging remains largely unknown. Here we performed a single-cell transcriptomic analysis of young and old
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::150287e0ef93db6ff75e178ce2188bc2
https://doi.org/10.1038/s41593-019-0491-3
https://doi.org/10.1038/s41593-019-0491-3
Autor:
Gerald Vinatier, Vincenzo G. Fiore, Edgar Buhl, Danielle C. Diaper, Benjamin L. de Bivort, Chenghao Chen, Raymond J. Dolan, Frank Hirth, Zoe N. Ludlow, Keita Endo, Yoshitsugu Adachi, Sheena Brown, James J L Hodge, Kei Ito, Nicholas J. Strausfeld, Stephan J. Sigrist, Daniel A. Solomon, Jean-René Martin, Alan Stepto, Katherine E. White, Dickon M. Humphrey, Sean M. Buchanan, Richard Faville, Ralf Stanewsky, Benjamin Kottler, Jonah Dearlove
Publikováno v:
BioRxiv
The insect central complex and vertebrate basal ganglia are forebrain centres involved in selection and maintenance of behavioural actions. However, little is known about the formation of the underlying circuits, or how they integrate sensory informa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2989c701ca55944611538ce5283e21
https://hal.archives-ouvertes.fr/hal-02413547
https://hal.archives-ouvertes.fr/hal-02413547
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Aging is the biggest risk factor for several neurodegenerative diseases. Parabiosis experiments have established that old mouse brains are improved by exposure to young mouse blood. Previously, our lab showed that delivery of Growth Differentiation F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c484a45e99c70cceb8724a9365be813
http://europepmc.org/articles/PMC6251885
http://europepmc.org/articles/PMC6251885
Autor:
Xian Adiconis, Stuart S. Levine, Brittany A Mayweather, Ruth Isserlin, Scott Lipnick, Vincent L. Butty, Lan Nguyen, Lee L. Rubin, Danielle Dionne, Methodios Ximerakis, Ceren Ozek, Sean M. Buchanan, Sean Simmons, Joshua Z. Levin, Brendan T. Innes, Zachary Niziolek, Aviv Regev, Gary D. Bader
The mammalian brain is complex, with multiple cell types performing a variety of diverse functions, but exactly how the brain is affected with aging remains largely unknown. Here we performed a single-cell transcriptomic analysis of young and old mou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c60c20399c61f2ce5f11971bb97f67
Autor:
Methodios, Ximerakis, Scott L, Lipnick, Brendan T, Innes, Sean K, Simmons, Xian, Adiconis, Danielle, Dionne, Brittany A, Mayweather, Lan, Nguyen, Zachary, Niziolek, Ceren, Ozek, Vincent L, Butty, Ruth, Isserlin, Sean M, Buchanan, Stuart S, Levine, Aviv, Regev, Gary D, Bader, Joshua Z, Levin, Lee L, Rubin
Publikováno v:
Nature neuroscience. 22(10)
The mammalian brain is complex, with multiple cell types performing a variety of diverse functions, but exactly how each cell type is affected in aging remains largely unknown. Here we performed a single-cell transcriptomic analysis of young and old
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da0e860102d58e106c1aae6eb44ab5f2
https://pubmed.ncbi.nlm.nih.gov/31551601
https://pubmed.ncbi.nlm.nih.gov/31551601