Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sean M, Lenahan"'
Autor:
Lauren A, Hinkel, Graham G, Willsey, Sean M, Lenahan, Korin, Eckstrom, Kristin C, Schutz, Matthew J, Wargo
Publikováno v:
Microbiology (Reading)
Glutamine amidotransferase-1 domain-containing AraC-family transcriptional regulators (GATRs) are present in the genomes of many bacteria, including all Pseudomonas species. The involvement of several characterized GATRs in amine-containing compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d040a599519f498d876f07096fb753f1
https://pubmed.ncbi.nlm.nih.gov/35266867
https://pubmed.ncbi.nlm.nih.gov/35266867
Publikováno v:
Cancer Research. 83:270-270
Non-small cell lung adenocarcinomas with concurrent oncogenic KRAS and SKT11 loss-of-function mutations represent an aggressive subtype that is characterized, in part, by increased metastasis and enhanced dependence on glutamine metabolism. The purpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf71c6629cf93b0130ddb99331280e2c
https://doi.org/10.1158/1538-7445.am2023-270
https://doi.org/10.1158/1538-7445.am2023-270
Autor:
Lauren A. Hinkel, Graham G. Willsey, Sean M. Lenahan, Korin Eckstrom, Kristin C. Schutz, Matthew J. Wargo
Glutamine amidotransferase-1 domain-containing AraC-family transcriptional regulators (GATRs) are present in the genomes of many bacteria, including all Pseudomonas species. The involvement of several characterized GATRs in amine-containing compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76afa91361c7b220dd3ddbd1c0b5cb7c
https://doi.org/10.1101/2021.11.02.466972
https://doi.org/10.1101/2021.11.02.466972
Autor:
Jenna G Eaton, Tyler C Hogan, Nikoletta Sidiropoulos, Cai L McCann, Hailey M. Sarausky, Kenneth J. Hampel, Gopika Nandagopal, David J. Seward, Paula B. Deming, Meagan A Lebeau, Margaret P Cameron, Jordan Armstrong, Sean M. Lenahan, Liam Donnelly
Publikováno v:
Carcinogenesis
Serine/Threonine Kinase 11 (STK11) encodes an important tumor suppressor that is frequently mutated in lung adenocarcinoma. Clinical studies have shown that mutations in STK11 resulting in loss of function correlate with resistance to anti-PD-1 monoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908e3f1d41dadc767c8d25e7486fca41
https://pubmed.ncbi.nlm.nih.gov/34849607
https://pubmed.ncbi.nlm.nih.gov/34849607
Publikováno v:
Cancer Research. 81:2706-2706
Our work demonstrates RNAscope allows simultaneous quantitative assessment of multiple transcripts in situ using formalin fixed paraffin embedded (FFPE) human non-small cell lung cancer (NSCLC) biopsies and suggests this methodology could be used as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e76c02aecb2fa79c1029408aed4cd3b2
https://doi.org/10.1158/1538-7445.am2021-2706
https://doi.org/10.1158/1538-7445.am2021-2706
Publikováno v:
Cancer Research. 81:2466-2466
Our work aims to delineate the molecular interactions linking somatic disruption of Serine-Threonine Kinase 11 (STK11) with anti-PD1 therapy resistance in KRAS-driven lung adenocarcinoma (LUAD). Data presented here suggests glutamine synthetase (GLUL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19ebb46f73f8ac6d68715f44b4d8dd60
https://doi.org/10.1158/1538-7445.am2021-2466
https://doi.org/10.1158/1538-7445.am2021-2466