Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Sean M, Decatur"'
Autor:
R. P. Redwine, Max Tegmark, Daniel Holz, Lawrence Wittner, Robert H. Socolow, Noam Chomsky, William Hartung, George F. Smoot, Suzanne Scarlata, Andrew Strominger, Val Moghadam, Stuart A. Newman, Joseph Cirincione, Gary R. Goldstein, Cornelia van der Ziel, Elaine Scarry, Richard J. Roberts, David M. Goldenberg, Sheldon Krimsky, Susan Solomon, Catherine A. Royer, Alan Robock, Peter C. Kahn, Jonathan King, Edward L. Loechler, Prasannan Parthasarathi, John F. Tierney, Joseph Gerson, David Ozonoff, Melissa Franklin, H. David Politzer, Eric J. Sundberg, Frank von Hippel, Martin Chalfie, Ira Helfand, Mriganka Sur, Sean M. Decatur, Michael B. VanElzakker, Henry H. Wortis, William D. Phillips
Publikováno v:
Science (New York, N.Y.). 369(6501)
The Trump administration is considering renewing nuclear weapons testing (1), a move that could increase the risk of another nuclear arms race as well as an inadvertent or intentional nuclear war. Following in the long tradition of scientists opposin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284c086bf0d3698a62e9f0e68f6fc514
https://pubmed.ncbi.nlm.nih.gov/32675367
https://pubmed.ncbi.nlm.nih.gov/32675367
Publikováno v:
Biochemistry. 52:6169-6181
γD-crystallin is an abundant structural protein of the lens that is found in native and modified forms in cataractous aggregates. We establish that UV-B irradiation of γD-crystallin leads to structurally specific modifications and precipitation via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bcb83f28c5370173dd6be8e28b7d317
https://doi.org/10.1021/bi4008353
https://doi.org/10.1021/bi4008353
Autor:
Jay B. Labov, Mary A. Smith, Sean M. Decatur, Sarah C. R. Elgin, Elvyra F. San Juan, Erin L. Dolan, Kerry Brenner, Susan R. Wessler, Gabriela C. Weaver, Wendy C. Newstetter, Laura Guertin, Gita Bangera
Publikováno v:
CBE life sciences education, vol 15, iss 2
Elgin, SCR; Bangera, G; Decatur, SM; Dolan, EL; Guertin, L; Newstetter, WC; et al.(2016). Insights from a Convocation: Integrating Discovery-Based Research into the Undergraduate Curriculum. CBE-LIFE SCIENCES EDUCATION, 15(2). doi: 10.1187/cbe.16-03-0118. UC Riverside: Retrieved from: http://www.escholarship.org/uc/item/5jt1b6x0
CBE Life Sciences Education
Elgin, SCR; Bangera, G; Decatur, SM; Dolan, EL; Guertin, L; Newstetter, WC; et al.(2016). Insights from a Convocation: Integrating Discovery-Based Research into the Undergraduate Curriculum. CBE-LIFE SCIENCES EDUCATION, 15(2). doi: 10.1187/cbe.16-03-0118. UC Riverside: Retrieved from: http://www.escholarship.org/uc/item/5jt1b6x0
CBE Life Sciences Education
The National Academies of Sciences, Engineering, and Medicine organized a convocation in 2015 to explore and elucidate opportunities, barriers, and realities of course-based undergraduate research experiences, known as CUREs, as a potentially integra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b1f8f9d1810e7a38db135a31d19d71
https://escholarship.org/uc/item/5jt1b6x0
https://escholarship.org/uc/item/5jt1b6x0
Publikováno v:
Journal of the American Chemical Society. 134:18410-18416
Identifying the sequence and structural content of residues that compose the core of amyloid fibrils is important because core regions likely control the process of fibril extension and provide potential drug targets. Human γD-crystallin is an eye l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d969c4d9b84e5659f8f11904af80049
https://doi.org/10.1021/ja307898g
https://doi.org/10.1021/ja307898g
Autor:
Sarah A. Petty, Sean M. Decatur
Publikováno v:
Proceedings of the National Academy of Sciences. 102:14272-14277
Many neurodegenerative diseases are characterized by the accumulation of amyloid fibers in the brain, which can occur when a protein misfolds into an extended β-sheet conformation. The nucleation of these β-sheet aggregates is of particular interes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf40a39ca1cd62a129932e8b4b32396f
https://doi.org/10.1073/pnas.0502804102
https://doi.org/10.1073/pnas.0502804102
Autor:
Wendy Barber-Armstrong, R. A. G. D. Silva, Sean M. Decatur, Timothy A. Keiderling, Rong Huang, Jan Kubelka
Publikováno v:
Journal of the American Chemical Society. 126:2346-2354
Infrared (IR) and vibrational circular dichroism (VCD) spectra were measured for a series of isotopically ((13)C on two or more amide Cdouble bond]O) labeled, 25 residue, alpha-helical peptides of the sequence Ac-(AAAAK)(4)AAAAY-NH(2) that were also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381ee7d963ca4306d6c5cb3f873665af
https://doi.org/10.1021/ja037998t
https://doi.org/10.1021/ja037998t
Autor:
Sean M. Decatur
Publikováno v:
Biopolymers. 54:180-185
The effect of N-acetylation on the conformation of alanine-rich helical peptides is examined using isotope-edited Fourier transform infrared (FTIR) spectroscopy. A series of peptides with sequence AA(AAKAA)(3)AAY has been prepared; each peptide incor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a823fd33e839770f3af2cd7ba85fe1f
https://doi.org/10.1002/1097-0282(200009)54:3<180::aid-bip40>3.0.co
https://doi.org/10.1002/1097-0282(200009)54:3<180::aid-bip40>3.0.co
Autor:
Steven G. Boxer, Dana D. Dlott, Chris W. Rella, Michael D. Fayer, Sean M. Decatur, Jeffrey R. Hill, Kristen A. Peterson
Publikováno v:
The Journal of Physical Chemistry. 100:12100-12107
Picosecond mid-IR pump-probe measurements of vibrational relaxation (VR) of CO bound to the active sites of wild-type and mutant myoglobins (Mb) reveal that an approximately linear relationship exists between the protein matrix-induced CO frequency s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a5ccaf3459df2e7f7a8cff21e9d67ef
https://doi.org/10.1021/jp9605414
https://doi.org/10.1021/jp9605414
Autor:
Stefan Franzen, William H. Woodruff, G D DePillis, R. B. Dyer, Sean M. Decatur, Steven G. Boxer
Publikováno v:
Biochemistry. 35:4939-4944
When nitric oxide (NO) binds to heme proteins, it exerts a repulsive trans effect on the proximal ligand, resulting in weakening or rupture of the proximal ligand-iron bond. The general question of whether NO binding generates a five-coordinate compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9958958951d78709dfd5d7fbc7bc5593
https://doi.org/10.1021/bi951661p
https://doi.org/10.1021/bi951661p
Publikováno v:
Biochemistry. 35:3925-3932
A variety of heterocyclic ligands can be exchanged into the proximal cavity of sperm whale myoglobin mutant H93G, providing a simple method for introduction of the equivalent of unnatural amino acid side chains into a functionally critical location i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8180d1866458f345962d5c4dcff464c4
https://doi.org/10.1021/bi952625t
https://doi.org/10.1021/bi952625t