Výsledky vyhledávání - "Sean M, Alber"

Cdk-inhibitors and exit from quiescence in primitive haematopoietic cell subsets

Autor: Richard, Steinman, Beatrice, Yaroslavskiy, Julie P, Goff, Sean M, Alber, Simon C, Watkins

Publikováno v: British journal of haematology. 124(3)

Prolonged quiescence of haematopoietic stem cells has been proposed to support durable haematopoiesis through clonal succession. Genetic experiments in mice have implicated the cyclin-dependent kinase inhibitor (cdki) p21Waf1 in sustaining stem cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5c97268bb0b07321e844b2230f0001a6
https://pubmed.ncbi.nlm.nih.gov/14717785

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Intratumoral delivery of dendritic cells engineered to secrete both interleukin (IL)-12 and IL-18 effectively treats local and distant disease in association with broadly reactive Tc1-type immunity

Autor: Tomohide, Tatsumi, Jian, Huang, William E, Gooding, Andrea, Gambotto, Paul D, Robbins, Nikola L, Vujanovic, Sean M, Alber, Simon C, Watkins, Hideho, Okada, Walter J, Storkus

Publikováno v: Cancer research. 63(19)

Dendritic cells (DCs) were adenovirally engineered to constitutively and durably secrete the potent Th1-biasing cytokines interleukin (IL)-12 (AdIL12DC) and/or IL-18 (AdIL18DC) and evaluated for their ability to promote therapeutic antitumor immunity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::adadb7d61011380e63ddec781afc5191
https://pubmed.ncbi.nlm.nih.gov/14559827

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