Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sean Korpela"'
Autor:
Ayman Oweida, Shelby Lennon, Dylan Calame, Sean Korpela, Shilpa Bhatia, Jaspreet Sharma, Caleb Graham, David Binder, Natalie Serkova, David Raben, Lynn Heasley, Eric Clambey, Raphael Nemenoff, Sana D. Karam
Publikováno v:
OncoImmunology, Vol 6, Iss 10 (2017)
Immunotherapy clinical trials targeting the programmed-death ligand axis (PD-1/PD-L1) show that most head and neck squamous cell carcinoma (HNSCC) patients are resistant to PD-1/PD-L1 inhibition. We investigated whether local radiation to the tumor c
Externí odkaz:
https://doaj.org/article/f9a1cb9e27b3433b91a38d8b7114157f
Autor:
Jacob Calhoun, Raphael A. Nemenoff, Lynn E. Heasley, Trista K. Hinz, Sana D. Karam, Jihye Kim, Robert L. Ferris, Sean Korpela, Ayman Oweida, Eric T. Clambey
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-15 (2021)
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-15 (2021)
Background Epidermal growth factor receptor (EGFR) is frequently amplified or overexpressed in head and neck squamous cell carcinoma (HNSCC) and is a clinically validated target for the therapeutic antibody, cetuximab, in the management of this cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a37cd941a57bca4453fe503b24426ab
https://doi.org/10.1186/s12967-021-02706-8
https://doi.org/10.1186/s12967-021-02706-8
Autor:
Trista K. Hinz, Colin Sempeck, Lindsay Marek, Bonnie L. Bullock, Howard Li, Daniel J Sisler, Natalia Gurule, Molishree Joshi, Raphael A. Nemenoff, Sean Korpela, Lynn E. Heasley
Publikováno v:
Molecular Cancer Research. 18:B51-B51
Mutations in the KRAS oncogene are frequent in lung adenocarcinomas (LUADs). Unfortunately, KRAS lacks a pharmacologically available inhibitor for precision oncology. Immunotherapies have recently become available and are now FDA approved for LUAD, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fdbac9e1593b206ef827e63eae3e253
https://doi.org/10.1158/1557-3125.ras18-b51
https://doi.org/10.1158/1557-3125.ras18-b51