Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sean K. Whittier"'
Autor:
Debaki R. Howlader, Rahul Shubhra Mandal, Ti Lu, Suhrid Maiti, Zackary K. Dietz, Sayan Das, Sean K. Whittier, Aaron C. Nagel, Satabdi Biswas, David J. Varisco, Francesca M. Gardner, Robert K. Ernst, William D. Picking, Wendy L. Picking
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Pseudomonas aeruginosa (Pa) is an opportunistic bacterial pathogen responsible for severe hospital acquired infections in immunocompromised and elderly individuals. Emergence of increasingly drug resistant strains and the absence of a broad-spectrum
Externí odkaz:
https://doaj.org/article/045977411a494c21b6ddb2526b664939
Autor:
Ti Lu, Murugesan Raju, Debaki R. Howlader, Zackary K. Dietz, Sean K. Whittier, David J. Varisco, Robert K. Ernst, Lyndon M. Coghill, William D. Picking, Wendy L. Picking
Publikováno v:
Vaccines, Vol 12, Iss 6, p 618 (2024)
Shigella spp. are responsible for bacillary dysentery or shigellosis transmitted via the fecal–oral route, causing significant morbidity and mortality, especially among vulnerable populations. There are currently no licensed Shigella vaccines. Shig
Externí odkaz:
https://doaj.org/article/c3f8050c393a4aa7b5ff75c873148e6a
Autor:
Ti Lu, Debaki R. Howlader, Sayan Das, Zackary K. Dietz, Aaron C. Nagel, Sean K. Whittier, William D. Picking, Wendy L. Picking
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Shigellosis (bacillary dysentery) is a severe diarrheal disease caused by members of the genus Shigella, which results in 90 million cases annually around the world. The Shigella type III secretion system (T3SS) is a specialized secretion sy
Externí odkaz:
https://doaj.org/article/2675dedfb313405db1995eb860661797
Autor:
Ti Lu, Sayan Das, Debaki R. Howlader, Akshay Jain, Gang Hu, Zackary K. Dietz, Qi Zheng, Siva Sai Kumar Ratnakaram, Sean K. Whittier, David J. Varisco, Robert K. Ernst, William D. Picking, Wendy L. Picking
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Shigellosis (bacillary dysentery) is a severe gastrointestinal infection with a global incidence of 90 million cases annually. Despite the severity of this disease, there is currently no licensed vaccine against shigellosis. Shigella’s primary viru
Externí odkaz:
https://doaj.org/article/96e7e423772c4f73a7467c187bacfbb4
Autor:
Sayan Das, Debaki R. Howlader, Ti Lu, Sean K. Whittier, Gang Hu, Simran Sharma, Zackary K. Dietz, Siva S. K. Ratnakaram, David J. Varisco, Robert K. Ernst, William D. Picking, Wendy L. Picking
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Salmonella enterica, a Gram-negative pathogen, has over 2500 serovars that infect a wide range of hosts. In humans, S. enterica causes typhoid or gastroenteritis and is a major public health concern. In this study, SseB (the tip protein of the Salmon
Externí odkaz:
https://doaj.org/article/66769d63d0b2439c90ca64d0abcce2b8
Autor:
Shoichi Tachiyama, Ryan Skaar, Yunjie Chang, Brittany L. Carroll, Meenakumari Muthuramalingam, Sean K. Whittier, Michael L. Barta, Wendy L. Picking, Jun Liu, William D. Picking
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Shigella flexneri, causative agent of bacillary dysentery (shigellosis), uses a type III secretion system (T3SS) as its primary virulence factor. The T3SS injectisome delivers effector proteins into host cells to promote entry and create an important
Externí odkaz:
https://doaj.org/article/0aaf6a10cbf3414396bc596f44958524
Autor:
Sayan Das, Debaki R. Howlader, Qi Zheng, Siva Sai Kumar Ratnakaram, Sean K. Whittier, Ti Lu, Johnathan D. Keith, William D. Picking, Susan E. Birket, Wendy L. Picking
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Infections caused by the opportunistic pathogen Pseudomonas aeruginosa can be difficult to treat due to innate and acquired antibiotic resistance and this is exacerbated by the emergence of multi-drug resistant strains. Unfortunately, no licensed vac
Externí odkaz:
https://doaj.org/article/034f98fdc226463a9a9ef6b1ecd76f43
Publikováno v:
Microorganisms, Vol 9, Iss 2, p 451 (2021)
Shigella comprises four species of human-restricted pathogens causing bacillary dysentery. While Shigella possesses multiple genetic loci contributing to virulence, a type III secretion system (T3SS) is its primary virulence factor. The Shigella T3SS
Externí odkaz:
https://doaj.org/article/c3608c232ccf473cbd0448bf587b7e3e
Autor:
Ti Lu, Sayan Das, Debaki R. Howlader, Qi Zheng, Siva Sai Kumar Ratnakaram, Sean K. Whittier, William D. Picking, Wendy L. Picking
Publikováno v:
Frontiers in Tropical Diseases. 2
Shigellosis is a severe diarrheal disease caused by members of the genus Shigella, with at least 80 million cases and 700,000 deaths annually around the world. The type III secretion system (T3SS) is the primary virulence factor used by the shigellae
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcf5914e3653fdc8876f8adadd8cbf2b
https://doi.org/10.3389/fitd.2021.729731
https://doi.org/10.3389/fitd.2021.729731
Autor:
William D. Picking, Wendy L. Picking, Jun Liu, Meenakumari Muthuramalingam, Michael L. Barta, Sean K. Whittier, Yunjie Chang, Shoichi Tachiyama, Ryan Skaar, Brittany L. Carroll
Shigella flexneri, causative agent of bacillary dysentery (shigellosis), uses a type III secretion system (T3SS) as its primary virulence factor. The T3SS injectisome delivers effector proteins into host cells to promote entry and create an important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0382a017dcac3aab3c059d1b579c28b
https://doi.org/10.1101/2021.05.13.444006
https://doi.org/10.1101/2021.05.13.444006
