Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sean J Markwardt"'
Autor:
Phyllis C Pugh, Elena W Adlaf, Chaunsheng eZhao, Sean J Markwardt, Cristin F Gavin, Jacques I Wadiche, Linda eOverstreet-Wadiche
Publikováno v:
Frontiers in Neuroscience, Vol 5 (2011)
The production and integration of adult-generated neurons in the dentate gyrus is dramatically perturbed by a variety of pathological insults, including repetitive seizures and hypoxia/ischemia. Less is known about how insults affect early postnatal
Externí odkaz:
https://doaj.org/article/fb21aaca1e7c4f32aa80c87dd31cb5f4
Autor:
Jacques I. Wadiche, Sean J. Markwardt, S. Alisha Epps, Linda Overstreet-Wadiche, Jose Carlos Gonzalez
Publikováno v:
The Journal of Neuroscience. 38:6513-6526
Sparse neural activity in the dentate gyrus is enforced by powerful networks of inhibitory GABAergic interneurons in combination with low intrinsic excitability of the principal neurons, the dentate granule cells (GCs). Although the cellular and circ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c6c215ac93356704c56a3a48e7eb55
https://doi.org/10.1523/jneurosci.0674-18.2018
https://doi.org/10.1523/jneurosci.0674-18.2018
Publikováno v:
The Journal of Neuroscience. 29:15063-15072
Adult neurogenesis is the multistage process of generating neurons from adult neural stem cells. Accumulating evidence indicates that GABAergic depolarization is an important regulator of this process. Here, we examined GABAergic signaling to newly g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134a34fa5183529b3e88a056c1e44546
https://doi.org/10.1523/jneurosci.2727-09.2009
https://doi.org/10.1523/jneurosci.2727-09.2009
Autor:
Aaron Chidekel, Thomas L. Miller, Sean J. Markwardt, Thomas H. Shaffer, Yan Zhu, Clifford J. Singhaus
Publikováno v:
American Journal of Perinatology. 25:481-489
We tested the hypothesis that hyperoxia or pressure exposure differentially activates expression of cytokines and/or matrix modeling proteins in human airway epithelial cells. Calu-3 epithelial cell monolayers were cultured on transwell plates with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58df5528ca92b28d5a251b220b0137b0
https://doi.org/10.1055/s-0028-1085067
https://doi.org/10.1055/s-0028-1085067
Publikováno v:
The Journal of Physiology. 586:3745-3749
New neurons are continuously generated in discrete regions of the adult brain. In the hippocampus, newly generated cells undergo a step-wise progression of maturation that is regulated at multiple stages by a variety of physiological and pathological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20b00eb93865fd30be2ec7b156a8a06c
https://doi.org/10.1113/jphysiol.2008.155713
https://doi.org/10.1113/jphysiol.2008.155713
Autor:
Susan C. Buckingham, Sean J. Markwardt, Yin Peng, Alicia M. Hall, Benjamin T. Throesch, Dax A. Hoffman, Qin Wang, Erik D. Roberson
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 35(15)
Neuronal hyperexcitability occurs early in the pathogenesis of Alzheimer's disease (AD) and contributes to network dysfunction in AD patients. In other disorders with neuronal hyperexcitability, dysfunction in the dendrites often contributes, but den
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf035c1eaeca10825258ea79a0be9fe2
https://pubmed.ncbi.nlm.nih.gov/25878292
https://pubmed.ncbi.nlm.nih.gov/25878292
Publikováno v:
Nature neuroscience
Depolarization by the neurotransmitter GABA regulates adult neurogenesis. Here we show that interneurons of the neurogliaform cell family are a primary source of GABA for newborn neurons in mouse dentate gyrus. GABAergic depolarization occurs in conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f6858d853bc2738fe1d4f4cee6a993
https://pubmed.ncbi.nlm.nih.gov/21983681
https://pubmed.ncbi.nlm.nih.gov/21983681
Autor:
Jacques I. Wadiche, Elena W Adlaf, Linda Overstreet-Wadiche, Sean J. Markwardt, Chaunsheng Zhao, Cristin F. Gavin, Phyllis C. Pugh
Publikováno v:
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 5 (2011)
Frontiers in Neuroscience, Vol 5 (2011)
The production and integration of adult-generated neurons in the dentate gyrus is dramatically perturbed by a variety of pathological insults, including repetitive seizures and hypoxia/ischemia. Less is known about how insults affect early postnatal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422b5e8cebff8df596d499642aab337a
https://doi.org/10.3389/fnins.2011.00045
https://doi.org/10.3389/fnins.2011.00045
Autor:
James H. Meador-Woodruff, Sean J. Markwardt, Rita M. Cowell, Jiandie D. Lin, Elizabeth K. Lucas, Linda Overstreet-Wadiche, Swati Gupta
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 30(21)
The transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) is a master regulator of metabolism in peripheral tissues, and it has been proposed that PGC-1alpha plays a similar role in the brain. Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0428f05d1e0f5b860f674c9f23fc853
https://pubmed.ncbi.nlm.nih.gov/20505089
https://pubmed.ncbi.nlm.nih.gov/20505089