Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sean Hindley"'
Publikováno v:
Separation Science and Technology ISBN: 9780323884877
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a909eb4d957fb096b7051bff694e71cf
https://doi.org/10.1016/b978-0-323-88487-7.00003-6
https://doi.org/10.1016/b978-0-323-88487-7.00003-6
Autor:
Nigel Stephen Stevenage Watson, Champa Patel, Steven John Coote, Henry Anderson Stevenage Kelly, Neil Anthony Pegg, Andrew Lowdon, William Leonard Mitchell, Rhian Thomas, Pamela J Thomas, Edward McDonald, Sean Hindley, Andrew Baxter, Martin Pass, Chi-Man Tang, Andrew P Craven, Harry Finch, Dawn A Walker, Christopher J. Mooney, Said Abu-Rabie, Harren Jhoti, Simon Parry, Pan A. Procopiou, Richard Conroy, Nigel G Ramsden
Publikováno v:
Bioorganicmedicinal chemistry letters. 9(12)
A series of trans-fused lactams containing the indane nucleus has been prepared. Compound 19 has much enhanced plasma stability compared with its lactone counterpart and shows appreciable in vitro anticoagulant activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d3e00bc5795729c712e852bf8850d0
https://pubmed.ncbi.nlm.nih.gov/10397495
https://pubmed.ncbi.nlm.nih.gov/10397495
Autor:
Neil Anthony Pegg, Edward McDonald, Richard E. Bolton, Steven John Coote, Andrew Lowdon, Martin Pass, Jessica McLaren, Sean Hindley, Harry Finch, Champa Patel, Martin R. Owen, Chi-Man Tang, Simon Parry, Christopher J. Mooney
Publikováno v:
Bioorganicmedicinal chemistry letters. 9(3)
Synthesis of trans -fused lactones containing the indane nucleus has resulted in a series of potent acylating inhibitors of thrombin. As an example compound 11e has an apparent second order rate constant of 11×10 6 M −1 sec −1 for the inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d16c2b8be8882a69c666887130370f
https://pubmed.ncbi.nlm.nih.gov/10091697
https://pubmed.ncbi.nlm.nih.gov/10091697