Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sean E McGeary"'
Publikováno v:
eLife, Vol 11 (2022)
MicroRNAs (miRNAs), in association with Argonaute (AGO) proteins, direct repression by pairing to sites within mRNAs. Compared to pairing preferences of the miRNA seed region (nucleotides 2–8), preferences of the miRNA 3′ region are poorly unders
Externí odkaz:
https://doaj.org/article/215a66502c1541fea6bb99de0d44e083
Autor:
Li Li, Sarah Bowling, Qi Yu, Sean E. McGeary, Karel Alcedo, Bianca Lemke, Mark Ferreira, Allon M. Klein, Shou-Wen Wang, Fernando D. Camargo
SummaryCellular lineage histories along with their molecular states encode fundamental principles of tissue development and homeostasis. Current lineage-recording mouse models have limited barcode diversity and poor single-cell lineage coverage, thus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c1fcf11a867e877db2e0a032200eb77
https://doi.org/10.1101/2023.01.29.526062
https://doi.org/10.1101/2023.01.29.526062
Autor:
John L Rinn, Edward B. Chuong, Mark W. Feinberg, Junchao Shi, Jennifer Cable, Erwei Song, Matthew D. Simon, Qi Chen, Howard Y. Chang, Anna Marie Pyle, Sofia A. Quinodoz, Chun-Kan Chen, Edith Heard, Jonathan E. Henninger, Amanda E. Hargrove, Dhiraj Kumar, Jeremy E. Wilusz, Rory Johnson, Marco Marcia, Adelheid Lempradl, David L. Spector, Kannanganattu V. Prasanth, Joshua T. Mendell, Juan Pablo Unfried, Samie R. Jaffrey, Allison M Porman, Sean E. McGeary, Mukesh Kumar Lalwani, Murat C. Kalem, Ling-Ling Chen, Xuhang Liu, Tetsuro Hirose, Roza K. Przanowska, Xiaohua Shen, Lamia Wahba, Lin He, Sarah D. Diermeier, Lydia M. Contreras, Lynne E. Maquat
Publikováno v:
Ann N Y Acad Sci
The human transcriptome contains many types of noncoding RNAs, which rival the number of protein-coding species. From long noncoding RNAs (lncRNAs) that are over 200 nucleotides long to piwi-interacting RNAs (piRNAs) of only 20 nucleotides, noncoding
Publikováno v:
eLife. 11
MicroRNAs (miRNAs), in association with Argonaute (AGO) proteins, direct repression by pairing to sites within mRNAs. Compared to pairing preferences of the miRNA seed region (nucleotides 2–8), preferences of the miRNA 3′ region are poorly unders
MicroRNAs (miRNAs), in association with Argonaute (AGO) proteins, direct repression by pairing to sites within mRNAs. Compared to pairing preferences of the miRNA seed region (nucleotides 2–8), preferences of the miRNA 3′ region are poorly unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d2d2a950f9111eeb94155b0eb20b5e8
https://doi.org/10.1101/2021.04.13.439700
https://doi.org/10.1101/2021.04.13.439700
Autor:
Namita Bisaria, David P. Bartel, Gina M. Kelley, Sean E. McGeary, Kathy S. Lin, Charlie Y. Shi, Thy M. Pham
Publikováno v:
Science
Biochemical prediction of miRNA targeting MicroRNAs (miRNAs) regulate most human messenger RNAs and play essential roles in diverse developmental and physiological processes. Correctly predicting the function of each miRNA requires a better understan
Autor:
Kathy S. Lin, Sumeet Gupta, Sean E. McGeary, Timothy J. Eisen, Alexander O. Subtelny, Stephen W. Eichhorn, David P. Bartel
Publikováno v:
Elsevier
Mol Cell
Mol Cell
SummaryFor all but a few mRNAs, the dynamics of metabolism are unknown. Here, we developed an experimental and analytical framework for examining these dynamics for mRNAs from thousands of genes. mRNAs of mouse fibroblasts exit the nucleus with diver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59428b049d280e9d878e6f27effaaa51
Autor:
Markus Stoffel, Sean E. McGeary, Rémy Denzler, Alexandra C. Title, David P. Bartel, Vikram Agarwal
Publikováno v:
Molecular Cell
Elsevier
Molecular Cell, 64 (3)
Elsevier
Molecular Cell, 64 (3)
Summary Expression changes of competing endogenous RNAs (ceRNAs) have been proposed to influence microRNA (miRNA) activity and thereby regulate other transcripts containing miRNA-binding sites. Here, we find that although miRNA levels define the exte
MicroRNAs (miRNAs) act within Argonaute proteins to guide repression of mRNA targets. Although various approaches have provided insight into target recognition, the sparsity of miRNA–target affinity measurements has limited understanding and predic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd25bf4959d6933940b3831792bd550c