Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sean Curley"'
Autor:
Sarina Kajani, Sean Curley, Marcella E. O'Reilly, Xiaofei Yin, Eugene T. Dillon, Weili Guo, Kanishka N. Nilaweera, Lorraine Brennan, Helen M. Roche, Fiona C. McGillicuddy
Publikováno v:
Molecular Metabolism, Vol 56, Iss , Pp 101425- (2022)
Introduction: High-fat diet (HFD)-induced obesity impairs clearance of cholesterol through the Reverse Cholesterol Transport (RCT) pathway, with downregulation in hepatic expression of cholesterol and bile acid transporters, namely ABCG5/8 and ABCB11
Externí odkaz:
https://doaj.org/article/9a74e5c821be49dc9efd9343bc31251f
Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis
Autor:
Robyn Bruen, Sean Curley, Sarina Kajani, Daniel Crean, Marcella E. O’Reilly, Margaret B. Lucitt, Catherine G. Godson, Fiona C. McGillicuddy, Orina Belton
Publikováno v:
Cardiovascular Diabetology, Vol 16, Iss 1, Pp 1-13 (2017)
Abstract Background Macrophages play a pivotal role in atherosclerotic plaque development. Recent evidence has suggested the glucagon-like peptide-1 receptor (GLP-1R) agonist, liraglutide, can attenuate pro-inflammatory responses in macrophages. We h
Externí odkaz:
https://doaj.org/article/660410bee8c34ce48687fcbb5137dfe3
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 7, p 1971 (2018)
High-density lipoprotein (HDL) particles have experienced a turbulent decade of falling from grace with widespread demotion from the most-sought-after therapeutic target to reverse cardiovascular disease (CVD), to mere biomarker status. HDL is slowly
Externí odkaz:
https://doaj.org/article/0e7644cb54dc4d6ebfae51faf5a7bc30
Autor:
Sarina Kajani, Sean Curley, Marcella E. O'Reilly, Xiaofei Yin, Eugene T. Dillon, Weili Guo, Kanishka N. Nilaweera, Lorraine Brennan, Helen M. Roche, Fiona C. McGillicuddy
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 56, Iss, Pp 101425-(2022)
Molecular Metabolism, Vol 56, Iss, Pp 101425-(2022)
Introduction High-fat diet (HFD)-induced obesity impairs clearance of cholesterol through the Reverse Cholesterol Transport (RCT) pathway, with downregulation in hepatic expression of cholesterol and bile acid transporters, namely ABCG5/8 and ABCB11,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd64a6ca0d0d390204b0035129b8ef9
http://europepmc.org/articles/PMC8762459
http://europepmc.org/articles/PMC8762459
Autor:
M. O'Reilly, Mary Barry, Eugene T. Dillon, Fiona C. McGillicuddy, Sean Curley, Stephen Sheehan, Gina M. Lynch, Robyn Bruen, Orina Belton, Eoin P. Brennan, Sarina Kajani
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 370:447-458
We have shown that the glucagon-like peptide-1 receptor agonist (GLP-1RA) liraglutide (Lir) inhibits development of early atherosclerosis in vivo by modulating immune cell function. We hypothesized that Lir could attenuate pre-established disease by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e112bde1ea6f6cbadfb65dc9fff8274
https://doi.org/10.1124/jpet.119.258343
https://doi.org/10.1124/jpet.119.258343
Autor:
Sarina Kajani, Fiona C. McGillicuddy, Sean Curley, Helen M. Roche, M. O'Reilly, Sarah Mahayni
Publikováno v:
Personalized Nutrition as Medical Therapy for High-Risk Diseases ISBN: 9781315112374
Cardiovascular disease (CVD) remains the leading cause of death globally despite major advances in the medical management of this condition. A healthy lifestyle, which incorporates a healthy diet, has a pivotal role to play in the management of CVD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::898188700f89b537cd6791a6aebd3000
https://doi.org/10.1201/9781315112374-3
https://doi.org/10.1201/9781315112374-3
Publikováno v:
Molecular Nutrition & Food Research
Scope Metabolic inflammation is a classic hallmark of obesity that is associated with numerous cardiometabolic complications. Disturbances in fatty acid and cholesterol metabolism are evident in obesity and likely intricately linked to the developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2a881f733872cf505c928699333d36
https://pubmed.ncbi.nlm.nih.gov/32754976
https://pubmed.ncbi.nlm.nih.gov/32754976
Publikováno v:
Atherosclerosis. 315:e65-e66
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17fbebc5896af2211f854f09c5c9c3ff
https://doi.org/10.1016/j.atherosclerosis.2020.10.202
https://doi.org/10.1016/j.atherosclerosis.2020.10.202
Autor:
Liberty Mthunzi, Eugene T. Dillon, Stephen Fitzsimons, Sarina Kajani, Fiona C. McGillicuddy, Sean Curley, Gina M. Lynch, Robyn Bruen, M. O'Reilly, Orina Belton
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33(10)
Monocytes/macrophages drive progression and regression of atherosclerosis. Conjugated linoleic acid (CLA), an anti-inflammatory lipid, mediates atheroprotective effects. We investigated how CLA alters monocyte/macrophage phenotype during attenuated p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a233def09b11ced0251cab36a2443bb1
https://pubmed.ncbi.nlm.nih.gov/31284764
https://pubmed.ncbi.nlm.nih.gov/31284764
Autor:
Yvonne M. Lenighan, Sabine M. Harrison, Aidan P. Maloney, Sarina Kajani, Helen M. Roche, M. O'Reilly, Robyn Bruen, Frank J. Monahan, Sean Curley, Fiona C. McGillicuddy
Publikováno v:
Proceedings of the Nutrition Society. 78
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eadeec1e49ebbe8fef4c9a6f4ac2cf16
https://doi.org/10.1017/s0029665119000193
https://doi.org/10.1017/s0029665119000193