Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Sean C. Gehen"'
Autor:
Michael J. Bartels, Daland R. Juberg, Reza J. Rasoulpour, Sean C. Gehen, Jeffrey H. Driver, B. Bhaskar Gollapudi, Matthew W. Himmelstein, Claire Terry, Zhongyu June Yan, Ian van Wesenbeeck
Publikováno v:
Critical Reviews in Toxicology. 50:836-860
1,3-Dichloropropene (1,3-D; CAS #542-75-6) is a fumigant used for preplant treatment of soil to control parasitic nematodes and manage soil borne diseases for numerous fruit, vegetable, field and tree and vine crops across diverse global agricultural
Publikováno v:
Organic Process Research & Development. 23:2225-2233
Crop protection active ingredients and formulated products are essential tools for modern agriculture that serve to prevent yield loss related to insect, weed, or fungal pest pressure. Prior to com...
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 119
Under European Regulation (EC) No 1272/2008 on the classification, labelling and packaging of substances and mixtures (CLP), chemicals can be classified as carcinogenic if they are considered to induce tumours, increase tumour incidence and/or malign
Autor:
Colin D. Brown, Git Chung, Melissa Chan, Michael J. Bartels, Marco Corvaro, Claire Terry, Sean C. Gehen
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 116
A review of pharmacokinetic and metabolism studies show that triclopyr is well absorbed from the oral route in numerous species (≥80%), primarily as parent compound. Absorption is quite rapid in rats, dogs and human volunteers. Plasma or blood clea
Autor:
Stuart Hindle, Raja S. Settivari, Heli M. Hollnagel, Shannon M. Krieger, Sean C. Gehen, Darrell R. Boverhof
Publikováno v:
Current Opinion in Toxicology. 5:19-27
Assessment of potential adverse effects on the immune system is an important component of the chemical safety evaluation process. As alternative testing methods are rapidly evolving, there is a progressing interest to determine their practical implem
Publikováno v:
Regulatory Toxicology and Pharmacology. 82:99-110
Acute systemic (oral, dermal, inhalation) toxicity testing of agrochemical formulations (end-use products) is mainly needed for Classification and Labelling (CL B) for each formulation the acute oral toxicity is always equal or greater than the Acute
Autor:
Lynea Murphy, Robert T. Mingoia, Jeanne Y. Domoradzki, Claire Terry, Carrie R. Fleming, Sean C. Gehen, Michael J. Bartels
Publikováno v:
Regulatory Toxicology and Pharmacology. 117:104765
Autor:
Lawrence Milchak, Jane Rose, Sheung P. Ng, Monita Sharma, Kyle P. Glover, Jodie Melbourne, Alicia Paini, Kathryn Page, Wayne Spoo, Annie M. Jarabek, Brian Keyser, Hans Raabe, Peter S. Thorne, Lan Ma-Hock, Anna G. Maione, Jon A. Hotchkiss, Daniel M. Wilson, Patrudu S. Makena, Clive Roper, Kelly Ann Berube, Sean C. Gehen, Paul M. Hinderliter, Anita R. Iskandar, Patrick Hayden, David Allen, Emily N. Reinke, Amy J. Clippinger, Marianna Gaça, Michael B. Bolger, Holger Behrsing, Warren Casey, Karsta Luettich, Grace Patlewicz, Pilar Prieto, Michael DeLorme
New approaches are needed to assess the effects of inhaled substances on human health. These approaches will be based on mechanisms of toxicity, an understanding of dosimetry, and the use of in silico modeling and in vitro test methods. In order to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad61ae01e0ad0fe9a756ec6ecb363f88
Autor:
Amy J. Clippinger, Jodie Melbourne, Marianna Gaça, Miyoung Yoon, Annie M. Jarabek, Kelly Ann Berube, Grace Patlewicz, Daniel M. Wilson, Jon A. Hotchkiss, Mathieu Vinken, Sean C. Gehen, David Allen, Paul M. Hinderliter, Barbara Buckley, Dongeun Huh, Marco Corvaro, Anna Lowit, Michael J. Bartels, Ian Indans
Publikováno v:
Toxicol In Vitro
Inhalation toxicity testing, which provides the basis for hazard labeling and risk management of chemicals with potential exposure to the respiratory tract, has traditionally been conducted using animals. Significant research efforts have been direct
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 89
Analysis of the prevalence of health effects in large scale databases is key in defining testing strategies within the context of Integrated Approaches on Testing and Assessment (IATA), and is relevant to drive policy changes in existing regulatory t