Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Sean A. Miller"'
Autor:
Sean R. Miller, Matthew Schipper, Lars G. Fritsche, Ralph Jiang, Garth Strohbehn, Erkin Ötleş, Benjamin H. McMahon, Silvia Crivelli, Rafael Zamora‐Resendiz, Nithya Ramnath, Shinjae Yoo, Xin Dai, Kamya Sankar, Donna M. Edwards, Steven G. Allen, Michael D. Green, Alex K. Bryant
Publikováno v:
Cancer Medicine, Vol 13, Iss 21, Pp n/a-n/a (2024)
ABSTRACT Background The cumulative, health system‐wide survival benefit of immune checkpoint inhibitors (ICIs) is unclear, particularly among real‐world patients with limited life expectancies and among subgroups poorly represented on clinical tr
Externí odkaz:
https://doaj.org/article/9a3b346a3ce341aea34bb04656fb9eec
Autor:
Sean Macdonald Miller, Raffaela M. Abbriano, Andrei Herdean, Richard Banati, Peter J. Ralph, Mathieu Pernice
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract We investigated two non-ionising mutagens in the form of ultraviolet radiation (UV) and ethyl methanosulfonate (EMS) and an ionising mutagen (X-ray) as methods to increase fucoxanthin content in the model diatom Phaeodactylum tricornutum. We
Externí odkaz:
https://doaj.org/article/0ecdd3def584456880727f8a9cf75396
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Drosophila melanogaster is a valuable model organism for a wide range of biological exploration. The well-known advantages of D. melanogaster include its relatively simple biology, the ease with which it is genetically modified, the relatively low fi
Externí odkaz:
https://doaj.org/article/0185fd0c409a4643b75707c6223c0621
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/8ff4ddbe1890492ea054a98ccf8f077c
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Parkinson’s disease (PD) is the most common movement disorder and the second most prevalent neurodegenerative disease after Alzheimer’s disease. Despite decades of research, there is still no cure for PD and the complicated intricacies of the pat
Externí odkaz:
https://doaj.org/article/139e0587b1b24a5d84cce8038947a707
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Amyotrophic Lateral Sclerosis (ALS) is a complex polygenetic neurodegenerative disorder. Establishing a diagnosis for ALS is a challenging and lengthy process. By the time a diagnosis is made, the lifespan prognosis is only about two to 5 years. Gene
Externí odkaz:
https://doaj.org/article/db2f75e3fe3247d2810ba2d08fd391ed
Autor:
Robert Logan, Brian G. Williams, Maria Ferreira da Silva, Akash Indani, Nicolas Schcolnicov, Anjali Ganguly, Sean J. Miller
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Recent advancements in deep learning (DL) have made possible new methodologies for analyzing massive datasets with intriguing implications in healthcare. Convolutional neural networks (CNN), which have proven to be successful supervised algorithms fo
Externí odkaz:
https://doaj.org/article/de6eb187ba18483891777ff4e68cd3bf
Autor:
Sean Macdonald Miller, Raffaela M. Abbriano, Anna Segecova, Andrei Herdean, Peter J. Ralph, Mathieu Pernice
Publikováno v:
Marine Drugs, Vol 20, Iss 1, p 19 (2021)
Microalgal biotechnology shows considerable promise as a sustainable contributor to a broad range of industrial avenues. The field is however limited by processing methods that have commonly hindered the progress of high throughput screening, and con
Externí odkaz:
https://doaj.org/article/092cd6f0416e4df2ae596ad0677b13e6
Autor:
Frank Raven, Joseph F. Ward, Katarzyna M. Zoltowska, Yu Wan, Enjana Bylykbashi, Sean J. Miller, Xunuo Shen, Se Hoon Choi, Kevin D. Rynearson, Oksana Berezovska, Steven L. Wagner, Rudolph E. Tanzi, Can Zhang
Publikováno v:
EBioMedicine, Vol 24, Iss C, Pp 93-101 (2017)
A central pathogenic event of Alzheimer's disease (AD) is the accumulation of the Aβ42 peptide, which is generated from amyloid-β precursor protein (APP) via cleavages by β- and γ-secretase. We have developed a class of soluble 2-aminothiazole γ
Externí odkaz:
https://doaj.org/article/8a8ad0d1c493496387f9e9c4027a02a7
Autor:
Sean J. Miller
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Astrocytes are the most abundant cell type in the central nervous system (CNS), providing critical roles in the overall maintenance and homeostasis. Over 100 years ago, Cajal first showed morphological depictions of different astrocyte populations. S
Externí odkaz:
https://doaj.org/article/afbf8c23bb8042649fadba2db244204f