Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sean, Reuter"'
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115871 (2014)
Neuregulin 1 signaling plays an important role in cardiac trabecular development, and in sustaining functional integrity in adult hearts. Treatment with neuregulin 1 enhances adult cardiomyocyte differentiation, survival and/or function in vitro and
Externí odkaz:
https://doaj.org/article/c69ed058fd7c4bc3b1f31fdedd4e58f4
Autor:
Belal A. Mohamed, Karl Toischer, Sean Reuter, Stefan Engelhardt, Deepak Ramanujam, Loren J. Field, Sara Khadjeh, Wuqiang Zhu, Katrin Schäfer, Gerd Hasenfuss, Mark Hünlich
Publikováno v:
Journal of Clinical Investigation. 127:4285-4296
Induction of the cell cycle is emerging as an intervention to treat heart failure. Here, we tested the hypothesis that enhanced cardiomyocyte renewal in transgenic mice expressing cyclin D2 would be beneficial during hemodynamic overload. We induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0c21906a17138dd76152e04b357a6f
https://doi.org/10.1172/jci81870
https://doi.org/10.1172/jci81870
Autor:
Simon J. Conway, Mark H. Soonpaa, Xiao-Long Lu, Shien-Fong Lin, Wen Tao, Sean Reuter, Michael Rubart
Publikováno v:
Cardiovascular Research. 114:389-400
Aims Recent studies have demonstrated electrotonic coupling between scar tissue and the surrounding myocardium in cryoinjured hearts. However, the electrical dynamics occurring at the myocyte-nonmyocyte interface in the fibrotic heart remain undefine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8522f8bb1999619ef37c29f6247031c
https://doi.org/10.1093/cvr/cvx163
https://doi.org/10.1093/cvr/cvx163
Aims Doxorubicin (DOX) is a widely used and effective anti-cancer therapeutic. DOX treatment is associated with both acute and late onset cardiotoxicity, limiting its overall efficacy. Here, the impact of cardiomyocyte cell cycle activation was exami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f55eed4b5031e2d8ccf0df03395f2ed9
https://europepmc.org/articles/PMC6452322/
https://europepmc.org/articles/PMC6452322/
Autor:
Loren J. Field, Sean Reuter, Lincoln T. Shenje, Manuel Galiñanes, Mark H. Soonpaa, Keng Leong Ang, Michael Rubart
Publikováno v:
American Journal of Physiology-Cell Physiology. 298:C1603-C1609
Accurate nuclear identification is crucial for distinguishing the role of cardiac myocytes in intrinsic and experimentally induced regenerative growth of the myocardium. Conventional histologic analysis of myocyte nuclei relies on the optical section
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a09037c1278d35f46b66c3ec3e872b
https://doi.org/10.1152/ajpcell.00435.2009
https://doi.org/10.1152/ajpcell.00435.2009
Autor:
Angela, Stephenson, Guo-Ying, Huang, Gui-Yi, Huang, Ngoc-Thinh, Nguyen, Sean, Reuter, Jennifer L, McBride, Joseph C, Ruiz
Publikováno v:
Genomics. 83:1105-1115
msk, myocardial SNF1-like kinase, was originally isolated in a screen for kinases expressed during early cardiogenesis in the mouse. msk maps to the proximal end of mouse chromosome 17 in a region that is syntenic with human chromosome 21q22.3, where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56357ab65e33e5f26ccf1df6533606fc
https://doi.org/10.1016/j.ygeno.2003.12.007
https://doi.org/10.1016/j.ygeno.2003.12.007
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 12, p e115871 (2014)
PLoS ONE, Vol 9, Iss 12, p e115871 (2014)
Objectives Neuregulin 1 signaling plays an important role in cardiac trabecular development, and in sustaining functional integrity in adult hearts. Treatment with neuregulin 1 enhances adult cardiomyocyte differentiation, survival and/or function in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f07bce46521e421195af8e739feb65cf
http://europepmc.org/articles/PMC4278834
http://europepmc.org/articles/PMC4278834
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01257c0a0642813547bbf554fc759d83
https://doi.org/10.1096/fasebj.27.1_supplement.528.2
https://doi.org/10.1096/fasebj.27.1_supplement.528.2
Publikováno v:
European heart journal. 33(1)
Aims Although pharmacological interventions that mobilize stem cells and enhance their homing to damaged tissue can limit adverse post-myocardial infarction (MI) remodelling, cardiomyocyte renewal with this approach is limited. While experimental cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0df5248aaba580f9829a7ccbcef42eb
https://pubmed.ncbi.nlm.nih.gov/21849352
https://pubmed.ncbi.nlm.nih.gov/21849352
Autor:
Tanmoy Das Lala, Loren J. Field, Tyler Frounfelter, Jamie Grivas, Pascal J. Lafontant, Mary Ann Lesch, Alan R. Burns, Sean Reuter
Publikováno v:
Anatomical record (Hoboken, N.J. : 2007). 295(2)
The paucity of mammalian adult cardiac myocytes (CM) proliferation following myocardial infarction (MI) and the remodeling of the necrotic tissue that ensues, result in non-regenerative repair. In contrast, zebrafish (ZF) can regenerate after an apic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24190b3fe700865962184298f9e9b5cf
https://pubmed.ncbi.nlm.nih.gov/22095914
https://pubmed.ncbi.nlm.nih.gov/22095914