Výsledky vyhledávání

Predicting Severity of Radiation Induced Lymphopenia in Individual Proton Therapy Patients for Varying Dose Rate and Fractionation Using Dynamic 4-Dimensional Blood Flow Simulations

Autor: Lucas McCullum, Jungwook Shin, Stella Xing, Chris Beekman, Jan Schuemann, Theodore Hong, Dan Duda, Radhe Mohan, Steven H. Lin, Camilo M. Correa-Alfonso, Sean Domal, Julia Withrow, Wesley Bolch, Harald Paganetti, Clemens Grassberger

Publikováno v: International Journal of Radiation Oncology*Biology*Physics.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d11f30e2d0fc41a4309a2648b7badf85
https://doi.org/10.1016/j.ijrobp.2023.01.054

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Japanese pediatric and adult atomic bomb survivor dosimetry: potential improvements using the J45 phantom series and modern Monte Carlo transport

Autor: Keith T, Griffin, Tatsuhiko, Sato, Sachiyo, Funamoto, Konstantin, Chizhov, Sean, Domal, Colin, Paulbeck, Wesley, Bolch, Harry M, Cullings, Stephen, Egbert, Akira, Endo, Nolan, Hertel, Choonsik, Lee

Publikováno v: Radiation and environmental biophysics. 61(1)

The radiation exposure estimates for the atomic bomb survivors at Hiroshima and Nagasaki have evolved over the past several decades, reflecting a constant strive by the Radiation Effects Research Foundation (RERF) to provide thorough dosimetry to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::13b4d26ae8d61d26aa037a83e3a93756
https://pubmed.ncbi.nlm.nih.gov/34718851

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HEDOS-a computational tool to assess radiation dose to circulating blood cells during external beam radiotherapy based on whole-body blood flow simulations

Autor: Sean Domal, Julia Withrow, Jungwook Shin, Lucas McCullum, Clemens Grassberger, Wesley E. Bolch, Camilo A Correa, Harald Paganetti, Abdelkhalek Hammi, Shu Xing, Jennifer Pursley

Publikováno v: Phys Med Biol

We have developed a time-dependent computational framework, hematological dose (HEDOS), to estimate dose to circulating blood cells from radiation therapy treatment fields for any treatment site. Two independent dynamic models were implemented in HED

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6798fae32847e51b2a24a3d4fc9c7bcc
https://pubmed.ncbi.nlm.nih.gov/34293735

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A dynamic blood flow model to compute absorbed dose to circulating blood and lymphocytes in liver external beam radiotherapy

Autor: Shu Xing, Jungwook Shin, Jennifer Pursley, Camilo M Correa-Alfonso, Nicolas Depauw, Sean Domal, Julia Withrow, Wesley Bolch, Clemens Grassberger, Harald Paganetti

Publikováno v: Phys Med Biol

We have developed a novel 4D dynamic liver blood flow model, capable of accurate dose estimation to circulating blood cells during liver-directed external beam radiotherapy, accounting for blood recirculation and radiation delivery time structure. Ad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb6b404eba10b7db9b90d0d69f70ae77
https://doi.org/10.1088/1361-6560/ac4da4

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Dynamic Hepatic Blood Flow Model Shows Greater Impact of Total Treatment Time Than Integral Dose for Assessing Dose to Circulating Lymphocytes

Autor: Sean Domal, J. Withrow, Wesley E. Bolch, Harald Paganetti, Jennifer Pursley, John H. Shin, Clemens Grassberger, S. Xing, C. Alfonso

Publikováno v: International Journal of Radiation Oncology*Biology*Physics. 111:e88

Purpose/Objective(s) Radiation-induced lymphocyte depletion has been reported to correlate with survival rate in post-radiotherapy patients with hepatocellular carcinoma. This study aims to assess the impact of integral dose and treatment time on the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02589f1ef427db697ca5cf25f458cef9
https://doi.org/10.1016/j.ijrobp.2021.07.466

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