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Autor:
Sang G. Paik, Sea H. Min, Youn S. Song, Su J. Seo, Yhun Yhong Sheen, Chi W. Song, Kab Ryong Chae, Su H. Lee, Dae Y. Hwang, Hwa J. Lim, Yong K. Kim, Jung S. Cho
Publikováno v:
Experimental neurology. 186(1)
Mutations in the APP gene lead to enhanced cleavage by the beta- and gamma-secretase, and increased Abeta formation, which are tightly associated with Alzheimer's disease (AD)-like neuropathological changes. To examine whether depositions of Abeta by