The Insufficient Activation of RIG-I–Like Signaling Pathway Contributes to Highly Efficient Replication of Porcine Picornaviruses in IBRS-2 Cells

Autor: Weijun Cao, Xiangle Zhang, Kangli Li, Shuying Chen, Shasha Li, Yi Ru, Zixiang Zhu, Zheng Haixue, Xiangtao Liu, Fan Yang

Publikováno v: Molecular & Cellular Proteomics : MCP

Seneca Valley virus (SVV) or commonly known as senecavirus A, is one of the picornavirus that is associated with vesicular disease and neonatal mortality in swine herds. Our previous study found that SVV replicates extremely faster in porcine Institu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4873e1635af9d11fcb25c17f248b6982
https://doi.org/10.1016/j.mcpro.2021.100147

InTRIMsic immunity: Positive and negative regulation of immune signaling by tripartite motif proteins

Autor: Gijs A. Versteeg, Adolfo García-Sastre, Stefan Benke, Ricardo Rajsbaum

Publikováno v: Cytokine & Growth Factor Reviews

During the immune response, striking the right balance between positive and negative regulation is critical to effectively mount an anti-microbial defense while preventing detrimental effects from exacerbated immune activation. Intra-cellular immune

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8510a75bcc7b791963c2adea3f1939
http://europepmc.org/articles/PMC7173094

All hands on deck: SARS-CoV-2 proteins that block early anti-viral interferon responses.

Autor: Setaro AC; Program in Immunology, Tufts Graduate School of Biomedical Sciences, USA.; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Tufts University, MA, USA., Gaglia MM; Program in Immunology, Tufts Graduate School of Biomedical Sciences, USA.; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Tufts University, MA, USA.

Publikováno v: Current research in virological science [Curr Res Virol Sci] 2021; Vol. 2, pp. 100015. Date of Electronic Publication: 2021 Nov 12.