Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Se-Myo Park"'
Autor:
Mi-Sun Choi, Se-Myo Park, Soojin Kim, Hyun Jegal, Hyang-Ae Lee, Hyoung-Yun Han, Seokjoo Yoon, Sang-Kyum Kim, Jung-Hwa Oh
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 280, Iss , Pp 116516- (2024)
The assessment of neurotoxicity for environmental chemicals is of utmost importance in ensuring public health and environmental safety. Multielectrode array (MEA) technology has emerged as a powerful tool for assessing disturbances in the electrophys
Externí odkaz:
https://doaj.org/article/1109831dd2084c1d9ddee85aeb091bf0
Autor:
Hyoung-Yun Han, Bo-Kyung Kim, Jinhyung Rho, Se-Myo Park, Mi-Sun Choi, Soojin Kim, Min Beom Heo, Young-Su Yang, Jung-Hwa Oh, Tae Geol Lee, Seokjoo Yoon
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Cerium oxide nanoparticles (CeO2 NPs, NM-212) are well-known for their catalytic properties and antioxidant potential, and have many applications in various industries, drug delivery, and cosmetic formulations. CeO2 NPs exhibit strong antimi
Externí odkaz:
https://doaj.org/article/1b66a2d4ca9b4c10b99a0a6a3ef55664
Autor:
Se-Myo Park, Mi-Sun Choi, Soojin Kim, Hyun Jegal, Hyoung-Yun Han, Hyang Sook Chun, Sang Kyum Kim, Jung-Hwa Oh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract In the field of drug discovery, natural products have emerged as therapeutic agents for diseases such as cancer. However, their potential toxicity poses significant obstacles in the developing effective drug candidates. To overcome this limi
Externí odkaz:
https://doaj.org/article/e5c04e9dad1b4cf9abacfb09baf4044c
Publikováno v:
Toxicological Research. 39:201-211
Autor:
Nguyen Thi Hai Yen, Jung-Hwa Oh, Nguyen Thi Van Anh, Quoc-Viet Le, Se-Myo Park, Young Jin Park, Yong-Soon Cho, Kyoung-Sik Moon, Huy Truong Nguyen, Jae-Gook Shin, Nguyen Phuoc Long, Dong Hyun Kim
Publikováno v:
Chemico-Biological Interactions. 375:110430
Autor:
Soo Jin Kim, Se-Myo Park, Jung-Hwa Oh, Mi-Sun Choi, Hyun Jegal, Hyoung-Yun Han, Jun-Ho Ahn, Seokjoo Yoon, Hyun-Soo Cho, Jaehwan Ahn
Publikováno v:
Toxicology Letters. 342:73-84
Trovafloxacin (TVX) is associated with idiosyncratic drug-induced liver injury (iDILI) and inflammation-mediated hepatotoxicity. However, the inflammatory stress-regulated mechanisms in iDILI remain unclear. Herein, we elucidated the novel role of tu
Autor:
Nguyen Thi Hai Yen, Se-Myo Park, Vo Thuy Anh Thu, Nguyen Ky Phat, Yong-Soon Cho, Seokjoo Yoon, Jae-Gook Shin, Dong Hyun Kim, Jung-Hwa Oh, Nguyen Phuoc Long
Publikováno v:
Life sciences. 306
Drug-induced nephrotoxicity is frequently reported. However, the mechanisms underlying nephrotoxic medications and their overlapping molecular events, which might have therapeutic value, are unclear. We performed a genome-wide analysis of gene expres
Autor:
Hyun Kil Shin, Hang-Suk Chun, Sangwoo Lee, Se-Myo Park, Daeui Park, Myung-Gyun Kang, Sungbo Hwang, Jung-Hwa Oh, Hyoung-Yun Han, Woo-Keun Kim, Seokjoo Yoon
Publikováno v:
Bioinformatics (Oxford, England). 38(18)
Summary Drug-induced liver injury (DILI) is a challenging endpoint in predictive toxicology because of the complex reactive metabolites that cause liver damage and the wide range of mechanisms involved in the development of the disease. ToxSTAR provi
Autor:
Soo Jin Kim, Jung-Hwa Oh, Seokjoo Yoon, Eun Hee Lee, Kyoung-Sik Moon, Mi-Sun Choi, Se-Myo Park
Publikováno v:
Molecular & Cellular Toxicology. 15:185-197
Cyclosporine A (CsA) is an immunosuppressant used to improve the rate of acute rejection and graft survival in transplant patients. However, CsA has serious adverse effects including high blood pressure as well as liver and kidney dysfunction. Althou
Autor:
Ho Yun Shin, Ju-Young Moon, Heeyoung Yang, Se-Myo Park, Jung-Hwa Oh, Oh-Hyeok Kwon, Kug-Seung Lee, Young-Chul Lee, Hyun Uk Lee, Moon Il Kim, Le Thi Nhu Ngoc, Kyung-Bok Lee
Publikováno v:
ACS biomaterials scienceengineering. 5(11)
In this study, novel biomedical properties of Ce-aminoclay (CeAC) were investigated through in vitro and in vivo assays. CeAC (≥500 μg/mL) can selectively kill cancer cells (A549, Huh-1, AGS, C33A, HCT116, and MCF-7 cells) while leaving most norma