Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Se-Hee Choe"'
Publikováno v:
Stem Cell Research, Vol 65, Iss , Pp 102977- (2022)
Cynomolgus monkeys, due to their close anatomical, genetic and physiological similarity to humans, have been employed as a popular laboratory non-human primate model over rodents. Primate animal induced pluripotent stem cell (iPSC) have been used to
Externí odkaz:
https://doaj.org/article/6d0a72699dd24ae0bfc185b0bf0931d9
Publikováno v:
Stem Cell Research, Vol 64, Iss , Pp 102887- (2022)
Cynomolgus monkeys, a non-human primate species, are genetically and physiologically similar to humans; hence, they have been employed as an ideal developmental and biomedical model. Non-human primate animals and their induced pluripotent stem cell (
Externí odkaz:
https://doaj.org/article/a31a22eaade84a509d16c171882434e4
Autor:
Hyeon-Mu Cho, Se-Hee Choe, Young-Hyun Kim, Hye-Ri Park, Hee-Eun Lee, Ja-Rang Lee, Sang-Je Park, Jae-Won Huh
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Transposable elements cause alternative splicing (AS) in different ways, contributing to transcript diversification. Alternative polyadenylation (APA), one of the AS events, is related to the generation of mRNA isoforms in 70% of human genes
Externí odkaz:
https://doaj.org/article/0b8e9df5dd3e4c8da179b4056626899f
Autor:
Se-Hee Choe, Sang-Je Park, Hyeon-Mu Cho, Hye-Ri Park, Ja-Rang Lee, Young-Hyun Kim, Jae-Won Huh
Publikováno v:
BMC Evolutionary Biology, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Alternative splicing (AS) generates various transcripts from a single gene and thus plays a significant role in transcriptomic diversity and proteomic complexity. Alu elements are primate-specific transposable elements (TEs) and c
Externí odkaz:
https://doaj.org/article/44089befd26c47d8b525acc51a3a083d
Autor:
Hyeon-Mu Cho, Sang-Je Park, Se-Hee Choe, Ja-Rang Lee, Sun-Uk Kim, Yeung-Bae Jin, Ji-Su Kim, Sang-Rae Lee, Young-Hyun Kim, Jae-Won Huh
Publikováno v:
BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background The BLOC1S2 gene encodes the multifunctional protein BLOS2, a shared subunit of two lysosomal trafficking complexes: i) biogenesis of lysosome-related organelles complex-1 and i) BLOC-1-related complex. In our previous study, we i
Externí odkaz:
https://doaj.org/article/768748c26a74478081caa40955346900
Autor:
Ja-Rang Lee, Dong-Sung Ryu, Sang-Je Park, Se-Hee Choe, Hyeon-Mu Cho, Sang-Rae Lee, Sun-Uk Kim, Young-Hyun Kim, Jae-Won Huh
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background The characterization of genomic or epigenomic variation in human and animal models could provide important insight into pathophysiological mechanisms of various diseases, and lead to new developments in disease diagnosis and clini
Externí odkaz:
https://doaj.org/article/ff7c7b47e6dc4f7e97c0865ab66c7e1f
Autor:
Sang-Je Park, Young-Hyun Kim, Gyu-Hwi Nam, Se-Hee Choe, Sang-Rae Lee, Sun-Uk Kim, Ji-Su Kim, Bo-Woong Sim, Bong-Seok Song, Kang-Jin Jeong, Youngjeon Lee, Young Il Park, Kyoung-Min Lee, Jae-Won Huh, Kyu-Tae Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 2, Pp 2386-2402 (2015)
The accumulation and aggregation of misfolded proteins in the brain, such as amyloid-β (Aβ) and hyperphosphorylated tau, is a neuropathological hallmark of Alzheimer’s disease (AD). Previously, we developed and validated a novel non-human primate
Externí odkaz:
https://doaj.org/article/a0aaa9208bb449b388e14901c01657f3
Autor:
Ja-Rang Lee, Young-Hyun Kim, Sang-Je Park, Se-Hee Choe, Hyeon-Mu Cho, Sang-Rae Lee, Sun-Uk Kim, Ji-Su Kim, Bo-Woong Sim, Bong-Seok Song, Kang-Jin Jeong, Youngjeon Lee, Yeung Bae Jin, Philyong Kang, Jae-Won Huh, Kyu-Tae Chang
Publikováno v:
International Journal of Genomics, Vol 2016 (2016)
TSEN54 encodes a subunit of the tRNA-splicing endonuclease complex, which catalyzes the identification and cleavage of introns from precursor tRNAs. Previously, we identified an AluSx-derived alternative transcript in TSEN54 of cynomolgus monkey. Rev
Externí odkaz:
https://doaj.org/article/7ac80996f06041b1813247f084b1fe9d
Autor:
Hyeon-Mu Cho, Sang Je Park, Young-Hyun Kim, Hye Ri Park, Jae-Won Huh, Hee Eun Lee, Yeung Bae Jin, Ja-Rang Lee, Kang Jin Jeong, Se-Hee Choe, Ji-Su Kim
Publikováno v:
Aging (Albany NY)
African green monkeys (AGMs, Chlorocebus aethiops) are Old World monkeys which are used as experimental models in biomedical research. Recent technological advances in next generation sequencing are useful for unraveling the genetic mechanisms underl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2eaf03b0534e379b2ace016d746f57f
http://europepmc.org/articles/PMC7834999
http://europepmc.org/articles/PMC7834999
Autor:
Sun-Uk Kim, Sang Je Park, Sang-Rae Lee, Ji-Su Kim, Ja-Rang Lee, Hyeon-Mu Cho, Young-Hyun Kim, Jae-Won Huh, Se-Hee Choe, Yeung Bae Jin
Publikováno v:
BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-11 (2019)
BMC Evolutionary Biology
BMC Evolutionary Biology
Background The BLOC1S2 gene encodes the multifunctional protein BLOS2, a shared subunit of two lysosomal trafficking complexes: i) biogenesis of lysosome-related organelles complex-1 and i) BLOC-1-related complex. In our previous study, we identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f70ac09ced6ffa72a77c7cb164116ca
http://link.springer.com/article/10.1186/s12862-019-1530-0
http://link.springer.com/article/10.1186/s12862-019-1530-0