Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Se Jin Im"'
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 9, Pp 1900-1908 (2024)
Abstract IL-2 therapy, which enhances the function of CD8 + T cells, was initially employed as the cornerstone of immunotherapy against cancer. However, the impact of this therapy extends beyond CD8 + T cells to cells expressing IL-2R, such as endoth
Externí odkaz:
https://doaj.org/article/c037250ab4e44db6a7e2d8df2d4facb1
Autor:
Solhwi Lee, Kunhee Lee, Hyeonjin Bae, Kyungmin Lee, Junghwa Lee, Junhui Ma, Ye Ji Lee, Bo Ryeong Lee, Woong-Yang Park, Se Jin Im
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Graft-versus-host disease (GvHD) is a severe complication of hematopoietic stem cell transplantation driven by activated allogeneic T cells. Here, we identify a distinct subset of T cell factor-1 (TCF1)+ CD8+ T cells in mouse allogeneic and
Externí odkaz:
https://doaj.org/article/79e590a45d854b2db27257c86a8713b8
Autor:
Se Jin Im, Solhwi Lee
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/9721cf5e6ecb4763ae887fec2e65d573
Autor:
Eun-Ji Park, Hyun-Soo Kim, Do-Hyoung Lee, Su-Min Kim, Joon-Sup Yoon, Ji-Min Lee, Se Jin Im, Ho Lee, Min-Woo Lee, Chang-Woo Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Brown adipose tissue (BAT) is a specialized thermogenic organ that undergoes high demands of protein synthesis during thermogenic adaptation. Here, the authors show that the cold responsive phosphatase Ssu72 is required for mRNA translation that affe
Externí odkaz:
https://doaj.org/article/47151d5b2a03480a94318f67e60038d5
Autor:
Junghwa Lee, Kyungmin Lee, Hyeonjin Bae, Kunhee Lee, Solhwi Lee, Junhui Ma, Kyungjo Jo, Ijun Kim, ByulA Jee, Minyong Kang, Se Jin Im
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
In chronic infections and cancer, exhausted CD8 T cells exhibit heterogeneous subpopulations. TCF1+PD-1+ progenitor exhausted CD8 T cells (Tpex) can self-renew and give rise to Tim-3+PD-1+ terminally differentiated CD8 T cells that retain their effec
Externí odkaz:
https://doaj.org/article/2a80f01110ac4e05b51841e2cd95b494
Publikováno v:
Microorganisms, Vol 10, Iss 9, p 1827 (2022)
In this study, we investigate the characteristics of two main clones of carbapenemase-producing Klebsiella pneumoniae isolates from South Korea, ST11 and ST307, including carbapenem-susceptible isolates. Antibiotic susceptibility, serotype or wzi all
Externí odkaz:
https://doaj.org/article/beffb27cdfe74626a137b9ae1d17b979
Autor:
David Lawson, Zachary S Buchwald, Tahseen H Nasti, Judong Lee, Christiane S Eberhardt, Se Jin Im, Walter Curran, Rafi Ahmed, Mohammad K Khan, Andreas Wieland
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Radiotherapy (RT) has been shown to stimulate an antitumor immune response in irradiated tumors as well as unirradiated distant sites (abscopal effect). Previous studies have demonstrated a role for the tumor-draining lymph node (LN) in me
Externí odkaz:
https://doaj.org/article/7c7d8658ae3d4abb9d68605872b992f4
Autor:
Se Jin Im, Sang In Yang, Se Hwan Yang, Dong Hoon Choi, So Young Choi, Hea Sook Kim, Do Soo Jang, Kyeong Sik Jin, Yo-Kyung Chung, Seung-Hee Kim, Sang Hoon Paik, Yoo Chang Park, Moon Koo Chung, Yong Bum Kim, Kang-Hyun Han, Kwan Yong Choi, Young Chul Sung
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24574 (2011)
Human IgG1 Fc has been widely used as a bioconjugate, but exhibits shortcomings, such as antibody- and complement-mediated cytotoxicity as well as decreased bioactivity, when applied to agonistic proteins. Here, we constructed a nonimmunogenic, noncy
Externí odkaz:
https://doaj.org/article/5a9c73e6d3dc46749be05e8572f27352
Publikováno v:
Biochemical and Biophysical Research Communications. 661:56-63
Autor:
Masao Hashimoto, Koichi Araki, Maria A. Cardenas, Peng Li, Rohit R. Jadhav, Haydn T. Kissick, William H. Hudson, Donald J. McGuire, Rebecca C. Obeng, Andreas Wieland, Judong Lee, Daniel T. McManus, James L. Ross, Se Jin Im, Junghwa Lee, Jian-Xin Lin, Bin Hu, Erin E. West, Christopher D. Scharer, Gordon J. Freeman, Arlene H. Sharpe, Suresh S. Ramalingam, Alex Pellerin, Volker Teichgräber, William J. Greenleaf, Christian Klein, Jorg J. Goronzy, Pablo Umaña, Warren J. Leonard, Kendall A. Smith, Rafi Ahmed
Publikováno v:
Nature. 610:173-181