Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Se Hoan Kim"'
Autor:
Seung Kyu Kang, Ju Han Bok, Jin Hee Ahn, Myung Ae Bae, Se Hoan Kim, Hee Yeon Kim, Gui Bin Lee, Sang Dal Rhee, Ki-Young Kim, Il Hyang Kim, Ji Seon Park, Deok Chan Ha, Kwon Sung-Wook, Won Hoon Jung, Jae Hong Lee, Sung-Hoon Ahn
Publikováno v:
ACS Medicinal Chemistry Letters. 3:88-93
A new series of cyclic sulfamide derivatives were synthesized and evaluated for their ability to inhibit 11β-HSD1. Among this series, 18e showed good in vitro activity toward human 11β-HSD1, selectivity against 11β-HSD2, microsomal stability, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64520dfb24140fb9ed4b449ea7db0b75
https://doi.org/10.1021/ml200226x
https://doi.org/10.1021/ml200226x
Autor:
Jae Hong Lee, Ki-Young Kim, Duck Chan Ha, So Young Chu, Banda Narsaiah, Sung-Hoon Ahn, Nam Sook Kang, Chi Hyun Kim, Sang Dal Rhee, Seung Kyu Kang, Jin Hee Ahn, Myung Ae Bae, Se Hoan Kim, Kwon Sung-Wook
Publikováno v:
Chemical and Pharmaceutical Bulletin. 59:46-52
In the continuation of our 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor research, cyclic sulfonamide derivatives with an acetamide group at the 2-position were synthesized and evaluated for their abilities to inhibit 11β-HSD1. Amon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883f6fb19842a4c6948e37c398b5f9c7
https://doi.org/10.1248/cpb.59.46
https://doi.org/10.1248/cpb.59.46
Autor:
Se Hoan Kim, Hyae Gyeong Cheon, Seung Kyu Kang, Jin Hee Ahn, Myung Ae Bae, Ki-Young Kim, Sung-Hoon Ahn, Sang Dal Rhee, Chi Hyun Kim, Su Hee Lee, Kwon Sung-Wook, Ravirala Ramu, Duck Chan Ha
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:1065-1069
A new series of cyclic sulfonamide derivatives was synthesized and evaluated for their ability to inhibit 11beta-HSD1. Cyclic sulfonamides with phenylacetyl substituents at the 2-position showed nanomolar inhibitory activities. Among them, compound 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb14491915e4b58fcde76ec3c561938
https://doi.org/10.1016/j.bmcl.2009.12.035
https://doi.org/10.1016/j.bmcl.2009.12.035
Publikováno v:
Journal of the Korean Chemical Society. 53:471-475
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::909aaf4ec258d577f959ab7ea8bad1ae
https://doi.org/10.5012/jkcs.2009.53.4.471
https://doi.org/10.5012/jkcs.2009.53.4.471
Publikováno v:
ChemInform. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bb7923c47467986e1b9b91b504fab40
https://doi.org/10.1002/chin.199802034
https://doi.org/10.1002/chin.199802034
Autor:
Mi Sik Shin, Jae Mok Lee, Sung-Soo Kim, Jeong Hyung Lee, Hyemin Kim, Sun Ho Jung, Jin Ah Kim, Sung Dae Park, Se Hoan Kim, Hyae Gyeong Cheon, Kwang Rok Kim, Sang Dal Rhee, Seung Kyu Kang, Jin Hee Ahn
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(18)
A series of novel indene N-oxide derivatives were prepared by various synthetic methods and evaluated for their ability to activate PPARgamma. The best PPARgamma agonist in this series was 9h, which showed an EC(50) value of 15 nM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d2efc9d69d1ff2f00b44fe07b67d19
https://pubmed.ncbi.nlm.nih.gov/17624777
https://pubmed.ncbi.nlm.nih.gov/17624777
Publikováno v:
Chemistry Letters. 37:1068-1069
Palladium-catalyzed carboalkoxylation of 2-bromo-3-phenylindenones in various alcoholic solvents afforded diverse alkyl 1-oxo-3-phenyl-1H-indene-2-carboxylates in high yields.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::887b0137421e916127bd66a1cb8acfe4
https://doi.org/10.1246/cl.2008.1068
https://doi.org/10.1246/cl.2008.1068
Publikováno v:
Chemistry Letters; 10/5/2008, Vol. 37 Issue 10, p28-28, 1p