Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Se Bok Jang"'
Autor:
Ling Jin, Eun-Yeong Kim, Tae-Wook Chung, Chang Woo Han, So Young Park, Jung Ho Han, Sung-Jin Bae, Jong Rok Lee, Young Woo Kim, Se Bok Jang, Ki-Tae Ha
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Most cancer cells primarily produce their energy through a high rate of glycolysis followed by lactic acid fermentation even in the presence of abundant oxygen. Pyruvate dehydrogenase kinase (PDK) 1, an enzyme responsible for aerobic glycoly
Externí odkaz:
https://doaj.org/article/d15a50f053bb481fa911ceb41d99105f
Publikováno v:
Biochemical and Biophysical Research Communications. 665:1-9
Publikováno v:
Biochemical and Biophysical Research Communications. 641:27-33
KRAS mutations occur in a quarter of all human cancers. When activated in its GTP-bound form, RAS stimulates diverse cellular systems, such as cell division, differentiation, growth, and apoptosis through the activations of various signaling pathways
Publikováno v:
Journal of Microbiology and Biotechnology. 32:1034-1040
Fas-associated death domain (FADD) is an adapter molecule that bridges the interaction between receptor-interacting protein 1 (RIP1) and aspartate-specific cysteine protease-8 (caspase-8). As the primary mediator of apoptotic cell death, caspase-8 ha
Autor:
So Myung Song, Shin Ae Kang, Hye Kyung Park, Dong Hee Kim, So Young Park, Se Bok Jang, Hak Sun Yu
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 12, p e0006979 (2018)
BACKGROUND:In previous studies, we suggested that Acanthamoeba is a new aero-allergen and that patients who showed positive results for the skin-prick test response to Acanthamoeba cross-reacted with several pollen allergens. Additionally, patients w
Externí odkaz:
https://doaj.org/article/f5f797b58b634a5da7edf648a4dbfe24
Publikováno v:
Cells, Vol 10, Iss 4, p 842 (2021)
The KRAS oncogene is mutated in approximately ~30% of human cancers, and the targeting of KRAS has long been highlighted in many studies. Nevertheless, attempts to target KRAS directly have been ineffective. This review provides an overview of the st
Externí odkaz:
https://doaj.org/article/5fce3a84e6b74f6b88cba955e4960685
Autor:
Mi Kyung Park, Hae-Jin Kim, Min Kyoung Cho, Shin Ae Kang, So Young Park, Se Bok Jang, Hak Sun Yu
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 11, p e0006516 (2018)
BACKGROUND:In a previous study, we found that Trichinella spiralis muscle larva excretory and secretory proteins (ES-P) most likely activate collagen synthesis via TGF-β/Smad signaling, and this event could influence collagen capsule formation. METH
Externí odkaz:
https://doaj.org/article/2f303045ae7c41098c7792d562c1825e
Autor:
Eun-Yeong Kim, Young Jun Koh, Hee-Jung Choi, Ling Jin, Tae-Wook Chung, Keuk-Jun Kim, Ki-Tae Ha, Se Bok Jang, Chang Woo Han
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 10, Pp 1-13 (2019)
Experimental & Molecular Medicine
Experimental & Molecular Medicine
Angiogenesis should be precisely regulated because disordered neovascularization is involved in the aggravation of multiple diseases. The vascular endothelial growth factor (VEGF)-A/VEGF receptor 2 (VEGFR-2) axis is crucial for controlling angiogenic
Autor:
Se Bok Jang, Chang Woo Han, Kang Hyun Park, Eun-Yeong Kim, So Young Park, Ki-Tae Ha, Tae-Wook Chung
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
The Warburg effect, wherein cancer cells prefer glycolysis rather than oxidative phosphorylation even under normoxic conditions, is a major characteristic of malignant tumors. Lactate dehydrogenase A (LDHA) is the main enzyme regulating the Warburg e
Autor:
Se Bok Jang, Sung-Jin Bae, MinJeong Kim, Jung Ho Han, Ki-Tae Ha, Inkyu Lee, Dongryeol Ryu, Hyeon Jin Kim
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5406, p 5406 (2021)
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5406, p 5406 (2021)
Resistance to anticancer therapeutics occurs in virtually every type of cancer and becomes a major difficulty in cancer treatment. Although 5-fluorouracil (5FU) is the first-line choice of anticancer therapy for gastric cancer, its effectiveness is l