Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Seónadh M. O'Leary"'
Autor:
Cilian Ó Maoldomhnaigh, Donal J. Cox, James J. Phelan, Morgane Mitermite, Dearbhla M. Murphy, Gina Leisching, Lorraine Thong, Seónadh M. O’Leary, Karl M. Gogan, Kate McQuaid, Amy M. Coleman, Stephen V. Gordon, Sharee A. Basdeo, Joseph Keane
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
In order to mount an appropriate immune response to infection, the macrophage must alter its metabolism by increasing aerobic glycolysis and concomitantly decreasing oxidative phosphorylation; a process known as the Warburg effect. Consequently, lact
Externí odkaz:
https://doaj.org/article/a9b01451cc7f44639429c99ff0a2bc3b
Autor:
Emer E. Hackett, Hugo Charles-Messance, Seónadh M. O’Leary, Laura E. Gleeson, Natalia Muñoz-Wolf, Sarah Case, Anna Wedderburn, Daniel G.W. Johnston, Michelle A. Williams, Alicia Smyth, Mireille Ouimet, Kathryn J. Moore, Ed C. Lavelle, Sinéad C. Corr, Stephen V. Gordon, Joseph Keane, Frederick J. Sheedy
Publikováno v:
Cell Reports, Vol 30, Iss 1, Pp 124-136.e4 (2020)
Summary: Increased glycolytic metabolism recently emerged as an essential process driving host defense against Mycobacterium tuberculosis (Mtb), but little is known about how this process is regulated during infection. Here, we observe repression of
Externí odkaz:
https://doaj.org/article/940d7725a10c42f3aa2a7e0bce32ab6d