Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Seán, Fitzgerald"'
Publikováno v:
Stroke: Vascular and Interventional Neurology, Vol 2, Iss 4 (2022)
Background Various mechanical thrombectomy devices including stent retrievers (STRs), contact aspiration (CA) catheters, and balloon guide catheters (BGCs) are used in both isolation and combination for the treatment of acute ischemic stroke. A new g
Externí odkaz:
https://doaj.org/article/568f8f6e1eeb4a9bbd076f6f2b4c9b17
Autor:
Daniela Dumitriu LaGrange, Vincent Braunersreuther, Isabel Wanke, Jatta Berberat, Siri Luthman, Seán Fitzgerald, Karen M. Doyle, Olivier Brina, Philippe Reymond, Alexandra Platon, Michel Muster, Paolo Machi, Pierre-Alexandre Poletti, Maria Isabel Vargas, Karl-Olof Lövblad
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundCharacterization of the clot occluding the arteries in acute ischemic stroke received ample attention, in terms of elucidating the relationship between the clot composition, its etiology and its amenability for pharmacological treatment and
Externí odkaz:
https://doaj.org/article/0dc71b9ca3f1446c851b2388faa5f075
Autor:
Gavin J Blake, Thomas Kiernan, Seán Fitzgerald, Stephen O'Connor, Liesbeth Rosseel, Andrew Simpkin, Diarmaid Cadogan, Niall Patrick Connolly, Darren Mylotte, James Crowley, Khalid AlHarbi, Sacchin Arockiam, Patrick Owens, Amal John
Publikováno v:
BMJ Open, Vol 11, Iss 4 (2021)
Aims To evaluate temporal trends of acute coronary syndromes (ACS) treated via percutaneous coronary intervention (PCI) throughout the COVID-19 outbreak in a European healthcare system affected but not overwhelmed by COVID-19-related pathology.Method
Externí odkaz:
https://doaj.org/article/e174c1041868446bba221dcbce64d110
Stromal TRIM28-associated signaling pathway modulation within the colorectal cancer microenvironment
Autor:
Seán Fitzgerald, Virginia Espina, Lance Liotta, Katherine M. Sheehan, Anthony O’Grady, Robert Cummins, Richard O’Kennedy, Elaine W. Kay, Gregor S. Kijanka
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-11 (2018)
Abstract Background Stromal gene expression patterns predict patient outcomes in colorectal cancer. TRIM28 is a transcriptional co-repressor that regulates an abundance of genes through the KRAB domain family of transcription factors. We have previou
Externí odkaz:
https://doaj.org/article/cb14ff19e39146839e9dcb9f4f27b837
Publikováno v:
JACC: Cardiovascular Interventions. 16:768-770
Autor:
Seán Fitzgerald, Shunli Wang, Daying Dai, Dennis H Murphree, Abhay Pandit, Andrew Douglas, Asim Rizvi, Ramanathan Kadirvel, Michael Gilvarry, Ray McCarthy, Manuel Stritt, Matthew J Gounis, Waleed Brinjikji, David F Kallmes, Karen M Doyle
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0225841 (2019)
Our aim was to assess the utility of a novel machine learning software (Orbit Image Analysis) in the histological quantification of acute ischemic stroke (AIS) clots. We analyzed 50 AIS blood clots retrieved using mechanical thrombectomy procedures.
Externí odkaz:
https://doaj.org/article/4a0cf10fd7234cfbbf1165ef64176f27
Autor:
Yang Liu, Waleed Brinjikji, Mehdi Abbasi, Daying Dai, Jorge L Arturo Larco, Sarosh Irfan Madhani, Adnan H Shahid, Oana Madalina Mereuta, Raul G Nogueira, Peter Kvamme, Kennith F Layton, Josser E Delgado Almandoz, Ricardo A Hanel, Vitor Mendes Pereira, Mohammed A Almekhlafi, Albert J Yoo, Babak S Jahromi, Matthew J Gounis, Biraj Patel, Seán Fitzgerald, Karen Doyle, Diogo C Haussen, Alhamza R Al-Bayati, Mahmoud Mohammaden, Leonardo Pisani, Gabriel Martins Rodrigues, Ike C Thacker, Yasha Kayan, Alexander Copelan, Amin Aghaebrahim, Eric Sauvageau, Andrew M Demchuk, Parita Bhuva, Jazba Soomro, Pouya Nazari, Donald Robert Cantrell, Ajit S Puri, John Entwistle, Ramanathan Kadirvel, Harry J Cloft, David F Kallmes, Luis Savastano
Publikováno v:
Journal of NeuroInterventional Surgery. 14:1248-1252
BackgroundCompositional and structural features of retrieved clots by thrombectomy can provide insight into improving the endovascular treatment of ischemic stroke. Currently, histological analysis is limited to quantification of compositions and qua
Autor:
Alan O'Hare, Sara Molina, Jeanette Carlqvist, Klearchos Psychogios, Dennis Dunker, Ágnes Vadász, Georgios Magoufis, Annika Nordanstig, Seán Fitzgerald, Ray McCarthy, Karen M. Doyle, Michael Gilvarry, Rosanna Rossi, Ciara Tierney, Katarina Jood, Alexandros Rentzos, John Thornton, István Szikora, Erik Ceder, Andrew Douglas, Petra Redfors, Sarah Power, Turgut Tatlisumak, Paul Brennan, Abhay Pandit, András Nagy, Oana Madalina Mereuta, Georgios Tsivgoulis
Publikováno v:
Journal of Neurology. 269:1913-1920
Background and purpose There is still much debate whether bridging-therapy [intravenous thrombolysis (IVT) prior to mechanical thrombectomy (MT)] might be beneficial compared to MT alone. We investigated the effect of IVT on size and histological com
Autor:
Josser E Delgado Almandoz, Mahmoud H Mohammaden, Eric Sauvageau, Amin Aghaebrahim, Albert J Yoo, Mehdi Abbasi, Alhamza R Al-Bayati, Pouya Nazari, Raul G Nogueira, Oana Madalina Mereuta, Kennith F. Layton, Jazba Soomro, David F. Kallmes, John J. Entwistle, Harry J. Cloft, Jorge L Arturo Larco, Biraj M Patel, Parita Bhuva, Diogo C Haussen, Seán Fitzgerald, Daying Dai, Vitor Mendes Pereira, Ike Thacker, Leonardo Pisani, Babak S. Jahromi, Mohammed A. Almekhlafi, Donald R. Cantrell, Peter Kvamme, Waleed Brinjikji, Yasha Kayan, A Copelan, Luis E. Savastano, Alexander Meves, Karen M. Doyle, Gabriel M Rodrigues, R Kadirvel, Ricardo A. Hanel, Ajit S. Puri, Andrew M. Demchuk, Matthew J. Gounis
Publikováno v:
Journal of NeuroInterventional Surgery. 14:356-361
BackgroundSeveral animal studies have demonstrated that mechanical thrombectomy (MT) for acute ischemic stroke (AIS) may cause vessel wall injury (VWI). However, the histological changes in human cerebral arteries following MT are difficult to determ
Autor:
Mehdi Abbasi, David F. Kallmes, Yang Liu, Jorge L Arturo Larco, Daying Dai, Seán Fitzgerald, Oana Madalina Mereuta, Luis E. Savastano, Andrew Douglas, Waleed Brinjikji, Karen M. Doyle
Publikováno v:
AJNR Am J Neuroradiol
BACKGROUND AND PURPOSE: Previous studies have successfully created blood clot analogs for in vitro endovascular device testing using animal blood of various species. Blood components vary greatly among species; therefore, creating clot analogs from h