Anti-CD19 chimeric antigen receptor T-cell therapy has less efficacy in Richter transformation than in de novo large B-cell lymphoma and transformed low-grade B-cell lymphoma.

Autor: Benjamini O; Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Hashomer, Israel; School of Medicine, Faculty of Medical and health Sciences, Aviv University, Tel-Aviv. ohad.benjamini@sheba.health.gov.il., Fried S; Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Hashomer, Israel; School of Medicine, Faculty of Medical and health Sciences, Aviv University, Tel-Aviv., Shouval R; Department of Medicine, Adult Bone Marrow Transplant Service, Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine Weill Cornell Medical College, New York., Flynn JR; Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York., Beyar-Katz O; Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel; The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa., Leslie LA; John Theurer Cancer Center, Hackensack, University Medical Center, Hackensack New Jersey., Zucherman T; Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa., Yerushalmi R; Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Hashomer, Israel; School of Medicine, Faculty of Medical and health Sciences, Aviv University, Tel-Aviv., Shem-Tov N; Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Hashomer, Israel; School of Medicine, Faculty of Medical and health Sciences, Aviv University, Tel-Aviv., Palomba ML; Department of Medicine, Adult Bone Marrow Transplant Service, Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine Weill Cornell Medical College, New York., Danylesko I; Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Hashomer, Israel; School of Medicine, Faculty of Medical and health Sciences, Aviv University, Tel-Aviv., Sdayoor I; Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Hashomer, Israel; School of Medicine, Faculty of Medical and health Sciences, Aviv University, Tel-Aviv., Malka H; Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa., Itzhaki O; Ella Lemelbaum Institute for Immuno Oncology, Chaim Sheba Medical Center, Hashomer., Suh H; John Theurer Cancer Center, Hackensack, University Medical Center, Hackensack New Jersey., Devlin SM; Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York., Marcus R; Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Hashomer, Israel; School of Medicine, Faculty of Medical and health Sciences, Aviv University, Tel-Aviv., Dahi PB; Department of Medicine, Adult Bone Marrow Transplant Service, Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine Weill Cornell Medical College, New York., Jacoby E; School of Medicine, Faculty of Medical and health Sciences, Aviv University, Tel-Aviv, Israel; Department of Pediatric Hematology-Oncology, Safra Children's Hospital, Chaim Sheba Medical Center, Hashomer., Shah GL; Department of Medicine, Adult Bone Marrow Transplant Service, Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York., Sauter CS; Department of Hematology and Medical Oncology, Cleveland Clinic, Cleveland, OH., Ip A; John Theurer Cancer Center, Hackensack, University Medical Center, Hackensack New Jersey, United States; Hackensack Meridian School of Medicine, Nutley, NJ., Perales MA; Department of Medicine, Adult Bone Marrow Transplant Service, Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine Weill Cornell Medical College, New York., Nagler A; Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Hashomer, Israel; School of Medicine, Faculty of Medical and health Sciences, Aviv University, Tel-Aviv., Shimoni A; Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Hashomer, Israel; School of Medicine, Faculty of Medical and health Sciences, Aviv University, Tel-Aviv., Scordo M; Department of Medicine, Adult Bone Marrow Transplant Service, Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine Weill Cornell Medical College, New York., Avigdor A; Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Hashomer, Israel; School of Medicine, Faculty of Medical and health Sciences, Aviv University, Tel-Aviv.

Publikováno v: Haematologica [Haematologica] 2024 Nov 01; Vol. 109 (11), pp. 3566-3577. Date of Electronic Publication: 2024 Nov 01.

Response rates of extra-nodal diffuse large B cell lymphoma to anti-CD19-CAR T cells: A real word retrospective multicenter study.

Autor: Beyar Katz O; Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel., Perry C; Department of Hematology, Sourasky Medical Center, Tel Aviv, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Grisariu-Greenzaid S; Department of Bone Marrow Transplantation and Cancer Immunotherapy, Hadassah Medical Center, Jerusalem, Israel.; Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel., Yehudai-Ofir D; Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel.; The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel., Luttwak E; Department of Hematology, Sourasky Medical Center, Tel Aviv, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Avni B; Department of Bone Marrow Transplantation and Cancer Immunotherapy, Hadassah Medical Center, Jerusalem, Israel.; Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel., Zuckerman T; Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel.; The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel., Sdayoor I; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Stepensky P; Department of Bone Marrow Transplantation and Cancer Immunotherapy, Hadassah Medical Center, Jerusalem, Israel.; Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel., Ringelstein-Harlev S; Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel.; The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel., Bar-On Y; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Bone Marrow Transplantation and Cellular Therapy, Sourasky Medical Center, Tel Aviv, Israel., Libster D; Department of Bone Marrow Transplantation and Cancer Immunotherapy, Hadassah Medical Center, Jerusalem, Israel.; Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel., Sharvit L; Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel., Amit O; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Bone Marrow Transplantation and Cellular Therapy, Sourasky Medical Center, Tel Aviv, Israel., Greenbaum U; Department of Hematology, Soroka University Medical center and Faculty of Health and Science, Ben Gurion University of the Negev, Beer Sheva, Israel., Gold R; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Bone Marrow Transplantation and Cellular Therapy, Sourasky Medical Center, Tel Aviv, Israel., Herishanu Y; Department of Hematology, Sourasky Medical Center, Tel Aviv, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Benyamini N; Department of Hematology, Sourasky Medical Center, Tel Aviv, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Avivi I; Department of Hematology, Sourasky Medical Center, Tel Aviv, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Ram R; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Bone Marrow Transplantation and Cellular Therapy, Sourasky Medical Center, Tel Aviv, Israel.

Publikováno v: European journal of haematology [Eur J Haematol] 2023 Jul; Vol. 111 (1), pp. 63-71. Date of Electronic Publication: 2023 Apr 10.