Zobrazeno 1 - 10
of 686
pro vyhledávání: '"Scudamore, Cl"'
Autor:
Courreges CJF; Laboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge, United Kingdom.; Department of Pathology, The University of Cambridge, Cambridge, United Kingdom., Davenport ECM; Laboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge, United Kingdom.; Royal Veterinary College, London, United Kingdom., Bilanges B; UCL Cancer Institute, University College London, London, United Kingdom., Rebollo-Gomez E; UCL Cancer Institute, University College London, London, United Kingdom., Hukelmann J; The School of Life Sciences, University of Dundee, Dundee, United Kingdom., Schoenfelder P; Laboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge, United Kingdom., Edgar JR; Department of Pathology, The University of Cambridge, Cambridge, United Kingdom., Sansom D; Institute of Immunity and Transplantation, University College London, London, United Kingdom., Scudamore CL; Royal Veterinary College, London, United Kingdom., Roychoudhuri R; Department of Pathology, The University of Cambridge, Cambridge, United Kingdom., Garden OA; Royal Veterinary College, London, United Kingdom., Vanhaesebroeck B; UCL Cancer Institute, University College London, London, United Kingdom., Okkenhaug K; Laboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge, United Kingdom.; Department of Pathology, The University of Cambridge, Cambridge, United Kingdom.
Publikováno v:
Frontiers in immunology [Front Immunol] 2024 Nov 27; Vol. 15, pp. 1374621. Date of Electronic Publication: 2024 Nov 27 (Print Publication: 2024).
Autor:
Brown N; Cancer Mechanisms and Biomarkers Group Radiation Effects Department, Radiation, Chemical and Environmental Hazards, UK Health Security Agency (UKHSA), Didcot OX11 ORQ, UK., Finnon R; Cancer Mechanisms and Biomarkers Group Radiation Effects Department, Radiation, Chemical and Environmental Hazards, UK Health Security Agency (UKHSA), Didcot OX11 ORQ, UK., Finnon P; Cancer Mechanisms and Biomarkers Group Radiation Effects Department, Radiation, Chemical and Environmental Hazards, UK Health Security Agency (UKHSA), Didcot OX11 ORQ, UK., McCarron R; Cancer Mechanisms and Biomarkers Group Radiation Effects Department, Radiation, Chemical and Environmental Hazards, UK Health Security Agency (UKHSA), Didcot OX11 ORQ, UK., Cruz-Garcia L; Cancer Mechanisms and Biomarkers Group Radiation Effects Department, Radiation, Chemical and Environmental Hazards, UK Health Security Agency (UKHSA), Didcot OX11 ORQ, UK., O'Brien G; Cancer Mechanisms and Biomarkers Group Radiation Effects Department, Radiation, Chemical and Environmental Hazards, UK Health Security Agency (UKHSA), Didcot OX11 ORQ, UK., Herbert E; The Royal Veterinary College, Hatfield, Herts AL9 7TA, UK., Scudamore CL; Mary Lyon Centre, MRC Harwell, Oxfordshire OX11 0RD, UK., Morel E; Cancer Mechanisms and Biomarkers Group Radiation Effects Department, Radiation, Chemical and Environmental Hazards, UK Health Security Agency (UKHSA), Didcot OX11 ORQ, UK., Badie C; Cancer Mechanisms and Biomarkers Group Radiation Effects Department, Radiation, Chemical and Environmental Hazards, UK Health Security Agency (UKHSA), Didcot OX11 ORQ, UK.
Publikováno v:
IScience [iScience] 2023 Aug 03; Vol. 26 (9), pp. 107530. Date of Electronic Publication: 2023 Aug 03 (Print Publication: 2023).
Autor:
Tibarewal P; Cancer Institute, University College London, London, UK., Rathbone V; Cancer Institute, University College London, London, UK., Constantinou G; Cancer Institute, University College London, London, UK., Pearce W; Cancer Institute, University College London, London, UK., Adil M; Cancer Institute, University College London, London, UK., Varyova Z; Cancer Institute, University College London, London, UK., Folkes L; Oxford Institute of Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK., Hampson A; Oxford Institute of Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK., Classen GAE; Cancer Institute, University College London, London, UK., Alves A; Cancer Institute, University College London, London, UK., Carvalho S; Cancer Institute, University College London, London, UK., Scudamore CL; Exepathology, Exmouth, UK., Vanhaesebroeck B; Cancer Institute, University College London, London, UK.
Publikováno v:
The Journal of pathology [J Pathol] 2022 Dec; Vol. 258 (4), pp. 382-394. Date of Electronic Publication: 2022 Oct 31.
Autor:
Bilanges, B, Alliouachene, S, Pearce, W, Morelli, D, Szabadkai, G, Chung, Y-L, Chicanne, G, Valet, C, Hill, JM, Voshol, PJ, Collinson, L, Peddie, C, Ali, K, Ghazaly, E, Rajeeve, V, Trichas, G, Srinivas, S, Chaussade, C, Salamon, RS, Backer, JM, Scudamore, CL, Whitehead, MA, Keaney, EP, Murphy, LO, Semple, RK, Payrastre, B, Tooze, SA, Vanhaesebroeck, B
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications
Nature Communications
Vps34 PI3K is thought to be the main producer of phosphatidylinositol-3-monophosphate, a lipid that controls intracellular vesicular trafficking. The organismal impact of systemic inhibition of Vps34 kinase activity is not completely understood. Here
Autor:
Yamamoto, A, Hester, J, Macklin, PS, Kawai, K, Uchiyama, M, Biggs, D, Bishop, T, Bull, K, Cheng, X, Cawthorne, E, Coleman, ML, Crockford, TL, Davies, B, Dow, LE, Goldin, R, Kranc, K, Kudo, H, Lawson, H, McAuliffe, J, Milward, K, Scudamore, CL, Soilleux, E, Issa, F, Ratcliffe, PJ, Pugh, CW
Publikováno v:
Journal of Clinical Investigation. 129(9)
Physiological effects of cellular hypoxia are sensed by prolyl hydroxylase (PHD) enzymes which regulate HIFs. Genetic interventions on HIF/PHD pathways reveal multiple phenotypes that extend the known biology of hypoxia. Recent studies unexpectedly i
Autor:
Rodrigues A; Mary Lyon Centre, MRC Harwell, UK., Beresford L; Mary Lyon Centre, MRC Harwell, UK., Scudamore CL; ExePathology, UK., Yon M; Mary Lyon Centre, MRC Harwell, UK.
Publikováno v:
Laboratory animals [Lab Anim] 2022 Oct; Vol. 56 (5), pp. 466-470. Date of Electronic Publication: 2022 Mar 31.
Autor:
Kelsall IR; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK., McCrory EH; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK., Xu Y; Cross-Faculty NMR Centre, Department of Life Sciences, Imperial College London, London, UK., Scudamore CL; Exepathology, Exeter, UK., Nanda SK; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK., Mancebo-Gamella P; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK., Wood NT; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK., Knebel A; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK., Matthews SJ; Cross-Faculty NMR Centre, Department of Life Sciences, Imperial College London, London, UK., Cohen P; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK.
Publikováno v:
The EMBO journal [EMBO J] 2022 Apr 19; Vol. 41 (8), pp. e109700. Date of Electronic Publication: 2022 Mar 11.
Autor:
Petrova T; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Bennett K; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom.; Division of Cell Signalling, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Nanda S; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Strickson S; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Scudamore CL; Exepathology, Exeter, Devon, United Kingdom., Prescott AR; Dundee Imaging Facility and Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Cohen P; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Publikováno v:
PloS one [PLoS One] 2022 Feb 14; Vol. 17 (2), pp. e0263151. Date of Electronic Publication: 2022 Feb 14 (Print Publication: 2022).
Autor:
Helke KL; Department of Comparative Medicine, Medical University of South Carolina, Charleston, South Carolina, USA., Meyerholz DK; Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA., Beck AP; Department of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA., Burrough ER; Veterinary Diagnostic and Production Animal Medicine Department, Iowa State University, Ames, Iowa, USA., Derscheid RJ; Veterinary Diagnostic and Production Animal Medicine Department, Iowa State University, Ames, Iowa, USA., Löhr C; Department of Biomedical Sciences, Oregon State University, Corvallis, Oregon, USA., McInnes EF; Toxicologic Pathology, Toxicology Section, Human Safety at Syngenta, in Jealott's Hill, Bracknell, United Kingdom., Scudamore CL; ExePathology, Pathologist at ExePathology, Exmouth, Devon, United Kingdom., Brayton CF; Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Publikováno v:
ILAR journal [ILAR J] 2021 Dec 31; Vol. 62 (1-2), pp. 133-168.
Autor:
Lana-Elola E; The Francis Crick Institute, London NW1 1AT, UK., Cater H; MRC Harwell Institute, Harwell Campus, Didcot, OX11 0RD, UK., Watson-Scales S; The Francis Crick Institute, London NW1 1AT, UK., Greenaway S; MRC Harwell Institute, Harwell Campus, Didcot, OX11 0RD, UK., Müller-Winkler J; The Francis Crick Institute, London NW1 1AT, UK., Gibbins D; The Francis Crick Institute, London NW1 1AT, UK., Nemes M; The Francis Crick Institute, London NW1 1AT, UK., Slender A; The Francis Crick Institute, London NW1 1AT, UK., Hough T; MRC Harwell Institute, Harwell Campus, Didcot, OX11 0RD, UK., Keskivali-Bond P; MRC Harwell Institute, Harwell Campus, Didcot, OX11 0RD, UK., Scudamore CL; MRC Harwell Institute, Harwell Campus, Didcot, OX11 0RD, UK., Herbert E; MRC Harwell Institute, Harwell Campus, Didcot, OX11 0RD, UK., Banks GT; MRC Harwell Institute, Harwell Campus, Didcot, OX11 0RD, UK., Mobbs H; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1QW, UK., Canonica T; School of Psychology, Cardiff University, Cardiff CF10 3AT, UK., Tosh J; The Francis Crick Institute, London NW1 1AT, UK.; UCL Queen Square Institute of Neurology, London WC1N 3BG, UK., Noy S; UCL Queen Square Institute of Neurology, London WC1N 3BG, UK., Llorian M; The Francis Crick Institute, London NW1 1AT, UK., Nolan PM; MRC Harwell Institute, Harwell Campus, Didcot, OX11 0RD, UK., Griffin JL; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1QW, UK.; Imperial College Dementia Research Institute, Imperial College London, London W12 7TA, UK., Good M; School of Psychology, Cardiff University, Cardiff CF10 3AT, UK., Simon M; MRC Harwell Institute, Harwell Campus, Didcot, OX11 0RD, UK., Mallon AM; MRC Harwell Institute, Harwell Campus, Didcot, OX11 0RD, UK., Wells S; MRC Harwell Institute, Harwell Campus, Didcot, OX11 0RD, UK., Fisher EMC; UCL Queen Square Institute of Neurology, London WC1N 3BG, UK., Tybulewicz VLJ; The Francis Crick Institute, London NW1 1AT, UK.; Department of Immunology and Inflammation, Imperial College London, London W12 0NN, UK.
Publikováno v:
Disease models & mechanisms [Dis Model Mech] 2021 Oct 01; Vol. 14 (10). Date of Electronic Publication: 2021 Oct 15.