Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Scrapie/metabolism"'
Publikováno v:
Biochimica et biophysica acta, vol. 1772, no. 6, pp. 681-691
Prions are unconventional infectious agents responsible for transmissible spongiform encephalopathies. Compelling evidences indicate that prions are composed exclusively by a misfolded form of the prion protein (PrPSc) that replicates in the absence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b9b72feb12dddb55dd46d60362ad91
Autor:
Sylvie L. Benestad, Wilhelm Wemheuer, Uwe Hahmann, Joanna Gawinecka, Inga Zerr, Ulf Schulze-Sturm, Bertram Brenig, Walter J. Schulz-Schaeffer, Ekkehard Schütz, Bjørn Bratberg, Wiebke M. Wemheuer, Olivier Andreoletti, Arne Wrede
Publikováno v:
American Journal of Pathology
American Journal of Pathology, American Society for Investigative Pathology, 2009, 175 (6), pp.2566-2573. ⟨10.2353/ajpath.2009.090623⟩
American Journal of Pathology, American Society for Investigative Pathology, 2009, 175 (6), pp.2566-2573. ⟨10.2353/ajpath.2009.090623⟩
Transmissible spongiform encephalopathies such as scrapie in sheep, Creutzfeldt-Jakob disease (CJD) in humans, and bovine sporadic encephalopathy in cattle are characterized by the accumulation of a misfolded protein: the pathological prion protein.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3602313ddf1f8844eda9b1e27e92e74
https://hal.inrae.fr/hal-02662349
https://hal.inrae.fr/hal-02662349
Autor:
Christopher R. Lowe, Denise V. Dear, Andrew C. Gill, Teresa J. T. Pinheiro, Jurate Kazlauskaite, Duncan S. Young, David Oxley, Judith Webster, Igor B. Bronstein, Filip Meersman
Publikováno v:
Dear, D V, Young, D S, Kazlauskaite, J, Meersman, F, Oxley, D, Webster, J, Pinheiro, T J T, Gill, A C, Bronstein, I & Lowe, C R 2007, ' Effects of post-translational modifications on prion protein aggregation and the propagation of scrapie-like characteristics in vitro ', BBA-Proteins and Proteomics, vol. 1774, no. 7, pp. 792-802 . https://doi.org/10.1016/j.bbapap.2007.05.005
Prion diseases, or transmissible spongiform encephalopathies (TSEs) are typically characterised by CNS accumulation of PrPSc, an aberrant conformer of a normal cellular protein PrPC. It is thought PrPSc is itself infectious and the causative agent of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf52871db917cd8e08cf79ae635ddb5
https://www.pure.ed.ac.uk/ws/files/10556109/dear792.pdf
https://www.pure.ed.ac.uk/ws/files/10556109/dear792.pdf
Publikováno v:
Hesketh, S, Sassoon, J, Knight, R, Hopkins, J & Brown, D R 2007, ' Elevated manganese levels in blood and central nervous system occur before onset of clinical signs in scrapie ', Journal of Animal Science, vol. 85, no. 6, pp. 1596-609 . https://doi.org/10.2527/jas.2006-714
Prion diseases, or transmissible spongiform encephalopathies, are neurodegenerative diseases that can only be accurately diagnosed by analysis of central nervous system tissue for the presence of an abnormal isoform of the prion protein known as PrP(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3094::d3f0d8c112abed0602e2b8e1ece1c51a
https://www.pure.ed.ac.uk/ws/files/14217160/Elevated_manganese_levels_in_blood_and_central_nervous_system_occur_before_onset_of_clinical_signs_in_scrapie.pdf
https://www.pure.ed.ac.uk/ws/files/14217160/Elevated_manganese_levels_in_blood_and_central_nervous_system_occur_before_onset_of_clinical_signs_in_scrapie.pdf
Autor:
Sanz-Casado, Elías1 elias@bib.uc3m.es, Ramírez-de Santa Pau, Margarita2 margarita.ramirez@madrid.org, Suárez-Balseiro, Carlos A.3 suarezbc03@yahoo.es, Iribarren-Maestro, Isabel1 iiribarr@bib.uc3m.es, de Pedro-Cuesta, Jesús4 jpedro@isciii.es
Publikováno v:
BMC Public Health. 2006, Vol. 6 Issue 1, p245-11. 11p.