Proinflammatory microglial activation impairs in vitro cortical tissue repair via zinc-dependent ADAM17 cleavage of the CSF-1 receptor.

Autor: Hernandez-Espinosa DR; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Medina-Ruiz GI; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Scrabis MG; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Thathiah A; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Aizenman E; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

Publikováno v: Journal of neurochemistry [J Neurochem] 2024 Oct 10. Date of Electronic Publication: 2024 Oct 10.

The Emerging Role of Microglial Hv1 as a Target for Immunomodulation in Myelin Repair.

Autor: Yingxin Tang¹, Xuan Wu¹, Jiarui Li¹, Yuanwei Li¹, Xiaoxiao Xu¹, Gaigai Li¹, Ping Zhang¹, Chuan Qin¹, Long-Jun Wu², Zhouping Tang¹ ddjtzp@163.com, Dai-Shi Tian¹ tiands@tjh.tjmu.edu.cn

Publikováno v: Aging & Disease. Jun2024, Vol. 15 Issue 3, p1176-1203. 28p.