Zobrazeno 1 - 10
of 1 226
pro vyhledávání: '"Scott. T. Weiss"'
Autor:
Tanawin Nopsopon, Yulu Chen, Qingwen Chen, Craig E. Wheelock, Scott. T. Weiss, Michael McGeachie, Jessica Lasky-Su, Ayobami Akenroye
Publikováno v:
ERJ Open Research, Vol 10, Iss 4 (2024)
Background There is limited evidence on biomarkers associated with response to the monoclonal antibodies currently approved for asthma treatment. We sought to identify circulatory metabolites associated with response to treatment with mepolizumab or
Externí odkaz:
https://doaj.org/article/586f865828d94072974804fb30f02c49
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/bec29f3360794ce297aa1800eb141bd5
Autor:
Georg Hahn, Sanghun Lee, Dmitry Prokopenko, Jonathan Abraham, Tanya Novak, Julian Hecker, Michael Cho, Surender Khurana, Lindsey R. Baden, Adrienne G. Randolph, Scott T. Weiss, Christoph Lange
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-18 (2022)
Abstract As of June 2022, the GISAID database contains more than 11 million SARS-CoV-2 genomes, including several thousand nucleotide sequences for the most common variants such as delta or omicron. These SARS-CoV-2 strains have been collected from p
Externí odkaz:
https://doaj.org/article/428c807d66334f48a8d811a6960611da
Autor:
Anna C. F. Lewis, Emma F. Perez, Anya E. R. Prince, Hana R. Flaxman, Lizbeth Gomez, Deanna G. Brockman, Paulette D. Chandler, Benjamin J. Kerman, Matthew S. Lebo, Jordan W. Smoller, Scott T. Weiss, Carrie L. Blout Zawatksy, James B. Meigs, Robert C. Green, Jason L. Vassy, Elizabeth W. Karlson
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-16 (2022)
Abstract Background Polygenic risk scores (PRS), which offer information about genomic risk for common diseases, have been proposed for clinical implementation. The ways in which PRS information may influence a patient’s health trajectory depend on
Externí odkaz:
https://doaj.org/article/b19f80c5d7664fe791e51eb803730865
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Here, using whole-metagenome shotgun sequencing data from patients with COVID-19 and controls, the authors reconstruct 11,584 microbial metagenome-assembled genomes (MAGs) including 5,403 non-redundant MAGs, revealing microbiota and metabolic pathway
Externí odkaz:
https://doaj.org/article/ab6bd8c8e5e642f895899fa7ecb394b5
Autor:
Jaehyun Joo, Angel C. Y. Mak, Shujie Xiao, Patrick M. Sleiman, Donglei Hu, Scott Huntsman, Celeste Eng, Mengyuan Kan, Avantika R. Diwakar, Jessica A. Lasky-Su, Scott T. Weiss, Joanne E. Sordillo, Ann C. Wu, Michelle Cloutier, Glorisa Canino, Erick Forno, Juan C. Celedón, Max A. Seibold, Hakon Hakonarson, L. Keoki Williams, Esteban G. Burchard, Blanca E. Himes
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Variability in response to short-acting β2-agonists (e.g., albuterol) among patients with asthma from diverse racial/ethnic groups may contribute to asthma disparities. We sought to identify genetic variants associated with bronchodilator r
Externí odkaz:
https://doaj.org/article/808f2b5b81bf46269caaa117e076f965
Autor:
Tian Ge, Marguerite R. Irvin, Amit Patki, Vinodh Srinivasasainagendra, Yen-Feng Lin, Hemant K. Tiwari, Nicole D. Armstrong, Barbara Benoit, Chia-Yen Chen, Karmel W. Choi, James J. Cimino, Brittney H. Davis, Ozan Dikilitas, Bethany Etheridge, Yen-Chen Anne Feng, Vivian Gainer, Hailiang Huang, Gail P. Jarvik, Christopher Kachulis, Eimear E. Kenny, Atlas Khan, Krzysztof Kiryluk, Leah Kottyan, Iftikhar J. Kullo, Christoph Lange, Niall Lennon, Aaron Leong, Edyta Malolepsza, Ayme D. Miles, Shawn Murphy, Bahram Namjou, Renuka Narayan, Mark J. O’Connor, Jennifer A. Pacheco, Emma Perez, Laura J. Rasmussen-Torvik, Elisabeth A. Rosenthal, Daniel Schaid, Maria Stamou, Miriam S. Udler, Wei-Qi Wei, Scott T. Weiss, Maggie C. Y. Ng, Jordan W. Smoller, Matthew S. Lebo, James B. Meigs, Nita A. Limdi, Elizabeth W. Karlson
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-16 (2022)
Abstract Background Type 2 diabetes (T2D) is a worldwide scourge caused by both genetic and environmental risk factors that disproportionately afflicts communities of color. Leveraging existing large-scale genome-wide association studies (GWAS), poly
Externí odkaz:
https://doaj.org/article/e049f828882147afa27dd2a692f0bc18
Autor:
Yen-Chen A. Feng, Ian B. Stanaway, John J. Connolly, Joshua C. Denny, Yuan Luo, Chunhua Weng, Wei-Qi Wei, Scott T. Weiss, Elizabeth W. Karlson, Jordan W. Smoller
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background As genomic sequencing moves closer to clinical implementation, there has been an increasing acceptance of returning incidental findings to research participants and patients for mutations in highly penetrant, medically actionable
Externí odkaz:
https://doaj.org/article/1d172a6eb2b243b18252e93e437d1df3
Autor:
Annika Röhl, Seung Han Baek, Priyadarshini Kachroo, Jarrett D. Morrow, Kelan Tantisira, Edwin K. Silverman, Scott T. Weiss, Amitabh Sharma, Kimberly Glass, Dawn L. DeMeo
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-15 (2022)
Abstract Background Chronic obstructive pulmonary disease (COPD) is a leading cause of death in adults that may have origins in early lung development. It is a complex disease, influenced by multiple factors including genetic variants and environment
Externí odkaz:
https://doaj.org/article/e3d56dd0cb3d4c459d401a6a75eb4a28
Autor:
Su H. Chu, Emily S. Wan, Michael H. Cho, Sergey Goryachev, Vivian Gainer, James Linneman, Erica J. Scotty, Scott J. Hebbring, Shawn Murphy, Jessica Lasky-Su, Scott T. Weiss, Jordan W. Smoller, Elizabeth Karlson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Electronic health records (EHR) provide an unprecedented opportunity to conduct large, cost-efficient, population-based studies. However, the studies of heterogeneous diseases, such as chronic obstructive pulmonary disease (COPD), often requ
Externí odkaz:
https://doaj.org/article/92a3cd4bff984a15bac3e86cb70bc9f3