Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Scott. C. Virgil"'
Publikováno v:
Journal of the American Chemical Society. 145:7763-7767
Autor:
Alexander W. Rand, Kevin J. Gonzalez, Christopher E. Reimann, Scott C. Virgil, Brian M. Stoltz
Publikováno v:
Journal of the American Chemical Society. 145:7278-7287
Autor:
Nicholas J. Hafeman, Steven A. Loskot, Christopher E. Reimann, Beau P. Pritchett, Scott C. Virgil, Brian M. Stoltz
Publikováno v:
Chemical Science. 14:4745-4758
The complete account of the total syntheses of scabrolide A and yonarolide is disclosed. This article describes an initial approach involving a bio-inspired macrocyclization/transannular Diels–Alder cascade, which ultimately failed due to undesired
Autor:
Tianyi Zhang, Alexander Q. Cusumano, Nicholas J. Hafeman, Steven A. Loskot, Christopher E. Reimann, Scott C. Virgil, William A. Goddard, Brian M. Stoltz
Publikováno v:
The Journal of Organic Chemistry. 87:14115-14124
We utilize ab initio quantum mechanics calculations to evaluate a range of plausible mechanistic pathways for the unexpected formation of a [6-4-4] ring system from an enone-olefin photocycloaddition in the synthesis of (-)-scabrolide A, previously r
Publikováno v:
ACS Central Science, Vol 3, Iss 4, Pp 278-282 (2017)
Externí odkaz:
https://doaj.org/article/26cdb333e19e48c0a93e6c953432b6a4
Autor:
Nicholas J. Hafeman, Melinda Chan, Tyler J. Fulton, Eric J. Alexy, Steven A. Loskot, Scott. C. Virgil, Brian M. Stoltz
Publikováno v:
Journal of the American Chemical Society. 144(44)
The first total synthesis of the furanobutenolide-derived cembranoid diterpenoid havellockate is disclosed. Our convergent strategy employs a Julia-Kocienski olefination to join two enantioenriched fragments to produce a diene that is subsequently us
Autor:
Yiyang Liu, Marc Liniger, Ryan M. McFadden, Jenny L. Roizen, Jacquie Malette, Corey M. Reeves, Douglas C. Behenna, Masaki Seto, Jimin Kim, Justin T. Mohr, Scott C. Virgil, Brian M. Stoltz
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 10, Iss 1, Pp 2501-2512 (2014)
Pd-catalyzed enantioselective alkylation in conjunction with further synthetic elaboration enables the formal total syntheses of a number of “classic” natural product target molecules. This publication highlights recent methods for setting quater
Externí odkaz:
https://doaj.org/article/53aff6b2b8524eb8bcb18875eaef6ba1
Autor:
Anand K. Muthusamy, Charlene H. Kim, Scott C. Virgil, Hailey J. Knox, Jonathan S. Marvin, Aaron L. Nichols, Bruce N. Cohen, Dennis A. Dougherty, Loren L. Looger, Henry A. Lester
Publikováno v:
Journal of the American Chemical Society, vol 144, iss 19
We report a reagentless, intensity-based S-methadone fluorescent sensor, iS-methadoneSnFR, consisting of a circularly permuted GFP inserted within the sequence of a mutated bacterial periplasmic binding protein (PBP). We evolved a previously reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53972a94019485a4a65506408d036e07
https://resolver.caltech.edu/CaltechAUTHORS:20220228-619163000
https://resolver.caltech.edu/CaltechAUTHORS:20220228-619163000
Autor:
Maryann Morales, Scott C. Virgil, Pinky Yadav, Zeev Gross, Atif Mahammed, Sally Khoury, Harry B. Gray
Publikováno v:
Organic Letters. 22:3119-3122
Separate focus on the oligomerization and oxidative cyclization steps required for the synthesis of 5,10,15-tris(trifluoromethyl)corrole revealed [bis(trifluoroacetoxy)iodo]benzene (PIFA) as a superior alternative oxidant. Under optimized conditions,
Autor:
Beau P. Pritchett, Brian M. Stoltz, Steven A. Loskot, Scott C. Virgil, Nicholas J Hafeman, Christopher E. Reimann
Publikováno v:
Journal of the American Chemical Society. 142:8585-8590
The first total synthesis of the norcembranoid diterpenoid scabrolide A is disclosed. The route begins with the synthesis of two chiral pool-derived fragments, which undergo a convergent coupling to expediently introduce all 19 carbon atoms of the na