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Impact of the F508del mutation on ovine CFTR, a Cl- channel with enhanced conductance and ATP-dependent gating.

Autor: Cai Z; School of Physiology and Pharmacology, University of Bristol, Medical Sciences Building, University Walk, Bristol, BS8 1TD, UK., Palmai-Pallag T; Human Molecular Genetics Program, Lurie Children's Research Center and Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60614, USA.; Harris Laboratory, formerly at the Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Khuituan P; School of Physiology and Pharmacology, University of Bristol, Medical Sciences Building, University Walk, Bristol, BS8 1TD, UK.; Center of Calcium and Bone Research, Department of Physiology, Faculty of Science, Mahidol University, Bangkok, 10400, Thailand., Mutolo MJ; Human Molecular Genetics Program, Lurie Children's Research Center and Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60614, USA., Boinot C; Institut de Physiologie et Biologie Cellulaires, Université de Poitiers, CNRS FRE 3511, 86022, Poitiers, France., Liu B; School of Physiology and Pharmacology, University of Bristol, Medical Sciences Building, University Walk, Bristol, BS8 1TD, UK., Scott-Ward TS; School of Physiology and Pharmacology, University of Bristol, Medical Sciences Building, University Walk, Bristol, BS8 1TD, UK., Callebaut I; IMPMC, Sorbonne Universités - UPMC Univ Paris 06, UMR CNRS 7590, Museum National d'Histoire Naturelle, IRD UMR 206, IUC, 75005, Paris, France., Harris A; Human Molecular Genetics Program, Lurie Children's Research Center and Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60614, USA., Sheppard DN; School of Physiology and Pharmacology, University of Bristol, Medical Sciences Building, University Walk, Bristol, BS8 1TD, UK.

Publikováno v: The Journal of physiology [J Physiol] 2015 Jun 01; Vol. 593 (11), pp. 2427-46. Date of Electronic Publication: 2015 Apr 09.

Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC.

Autor: Contreras-Sanz A; Department of Pharmaceutics, UCL School of Pharmacy, London, WC1N 1AX, UK., Scott-Ward TS, Gill HS, Jacoby JC, Birch RE, Malone-Lee J, Taylor KM, Peppiatt-Wildman CM, Wildman SS

Publikováno v: Purinergic signalling [Purinergic Signal] 2012 Dec; Vol. 8 (4), pp. 741-51. Date of Electronic Publication: 2012 Jun 16.

Chimeric constructs endow the human CFTR Cl- channel with the gating behavior of murine CFTR.

Autor: Scott-Ward TS; Department of Physiology and Pharmacology, University of Bristol, School of Medical Sciences, University Walk, Bristol BS8 1TD, United Kingdom., Cai Z, Dawson ES, Doherty A, Da Paula AC, Davidson H, Porteous DJ, Wainwright BJ, Amaral MD, Sheppard DN, Boyd AC

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2007 Oct 09; Vol. 104 (41), pp. 16365-70. Date of Electronic Publication: 2007 Oct 03.